CYCLIC DINUCLEOTIDE
AR110283B1Active Publication Date: 2026-08-28TAKEDA PHARMA CO LTD
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Patent Information
- Application Number
- ARP20170103344
- Authority / Receiving Office
- AR · AR
- Patent Type
- Patents
- Current Assignee / Owner
- Priority Date
- 2017-11-21
- Filing Date
- 2017-11-30
- Publication Date
- 2026-08-28
- Estimated Expiration
- 2037-11-30
Abstract
PROBLEM TO BE SOLVED: To provide a compound that has STING agonistic activity and is expected to be useful as an agent for the prevention or treatment of STING-related disease.SOLUTION: This invention relates to a compound represented by formula (I) [where each symbol is as described in the specifications] or a salt thereof.SELECTED DRAWING: None
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Claims
1. A cyclic dinucleotide compound characterized in that it has Formula (X): (FORMULA X), wherein R1 and R2 are each independently a hydroxyl group or a halogen atom; B1 is: (FORMULA); wherein R18 is hydrogen or C1-6 alkyl; R19 is a halogen atom; B2 is: (FORMULAS); Q2 and Q4 are each independently an oxygen atom or a sulfur atom, or a pharmaceutically acceptable salt thereof. Fourteen claims follow.