PURIFICATION OF RIFABUTIN FORMULATIONS

AR135759A1Pending Publication Date: 2026-10-21BIOVERSYS AG
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Patent Information

Application Number
ARP20250101030
Authority / Receiving Office
AR · AR
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-04-17
Filing Date
2025-04-16
Publication Date
2026-10-21
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Claims

Compositions and methods are provided for creating a rifabutin powder suitable for the preparation of intravenous formulations.

1. A purified rifabutin powder characterized in that subvisible particles have been removed therefrom.

7. A pharmaceutical composition characterized in that it comprises the rifabutin powder of any of claims 1-6 and a pharmaceutically acceptable solvent and / or excipient.

9. A method for producing rifabutin for intravenous administration, characterized in that it comprises: combining a rifabutin powder with an alkane solvent to create a mixture; exposing the mixture to a solid-liquid extraction process; and extracting purified rifabutin from the mixture.