Compositions and methods for increasing the efficacy of immunotherapies and vaccines

Abstract

Abstract This invention relates generally to compositions and methods for increasing the efficacy of immunotherapies and vaccines. In particular, the present invention relates to elevating the richness and diversity of a subject's gut microbiome through administration of an agent (e.g., fiber containing prebiotic agent (e.g., epigallocatechin gallate (EGCG), fucoidan, potato 5 starch, oligofructose and inulin)) (e.g., melatonin) with an immunotherapy or vaccine. Such compositions and methods are useful for treating cancer, infectious pathogens, autoimmune diseases, neurological disorders, and / or obesity. Abstract 5 20 26 22 03 19 21 A ug 2 02 6 A b s t r a c t 2 0 2 6 2 2 0 3 1 9 2 1 A u g 2 0 2 6 5

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