Toothpaste made with cocoa and medicinal plants.

Description

1 / 21 Toothpaste made with cocoa and medicinal plants. Field of Invention

[001] The invention pertains to the field of oral care products, specifically to the formulation of toothpastes that utilize natural ingredients to promote oral and general health. Fundamentals of the invention

[002] The search for oral hygiene products that use natural ingredients and possess therapeutic properties has been a growing trend, reflected in the development of various toothpaste formulations that incorporate extracts of medicinal plants, essential oils, and natural compounds. Several inventions related to oral hygiene have already explored the properties of plant ingredients to offer additional benefits to oral health, beyond simply cleaning teeth (US 8491920 B2 - HENKEL AG & Co. KGaA, 2013); (EP 3175171 A1 - INTERMED SA, 2017); (CN 103740771 - AYUNNAN BAIYAO GROUP, 2014); (WO 2011090840 A1 NATURAL PRODUCTS Pty Ltd., 2011); (CN 101973922 B - DABUR INDIA Limited, 2011). However, none of them explore the properties of cocoa for oral health. Toothpastes with Extracts of Medicinal Plants

[003] Previous patents demonstrate the inclusion of plant extracts such as chamomile, peppermint and sage extract (US 8491920 B2); myrrh, chamomile, echinacea and oak bark (EP 3175171 A1); green tea, chamomile and Aloe vera extracts (CN 103740771 A); in toothpaste formulations. Plants that are known for their anti-inflammatory, antimicrobial and soothing properties, being used to prevent gum inflammation and aid in the healing of oral wounds. Use of Cocoa in Oral Hygiene Products

[004] Although the use of cocoa in cosmetic and food products is well established, its application in toothpaste is still an emerging innovation. Research indicates that cocoa compounds, such as theobromine and flavonoids, Petition 870240108569, dated 12 / 19 / 2024, page 7 / 28 2 / 21 may strengthen tooth enamel and offer antioxidant properties, but there is little exploration of this in the oral hygiene market. Theobromine has been considered as a substitute for fluoride due to its ability to remineralize tooth enamel. Xylitol and Peppermint Essential Oil in Toothpastes

[005] Xylitol, a sugar alcohol with anticariogenic properties, is widely used in toothpastes due to its ability to prevent cavities. Studies show that xylitol inhibits the growth of cariogenic bacteria and stimulates saliva production, promoting overall oral health (Mãkinen, 2010). Xylitol not only contributes to a pleasant taste but also stimulates saliva production, which aids in the remineralization of tooth enamel and the maintenance of oral health (Lavigne et al., 2016; Hu et al., 2017). In synergy with mint, they produce a refreshing effect accompanied by salivary stimulation, improving oral health.

[006] As a replacement for menthol, frequently used in toothpastes for its refreshing effect and analgesic and antimicrobial properties, Mentha piperita essential oil emerges as a healthy alternative. Scientific research highlights that Mentha piperita essential oil has significant antimicrobial effects, contributing to the reduction of oral bacteria and providing a long-lasting feeling of freshness (Khan et al., 2012). In addition, the use of Mentha piperita essential oil may offer a superior safety profile and additional benefits for oral health compared to synthetic menthol. Other Relevant Plant Ingredients

[007] The formulation of toothpastes using ingredients such as Ginkgo biloba, cinnamon, cloves, and mint represents an innovative and effective approach to oral care. Ginkgo biloba, known for its potent antioxidant and vasodilating properties, significantly improves blood circulation in the gums, promoting gum tissue health and preventing periodontal problems (Gao et al., 2021). Cinnamon stands out for its robust antimicrobial properties, which effectively combat bacteria responsible for bad breath and periodontal disease, contributing to a cleaner and healthier mouth (Nostro et al., 2004). Cloves, rich in eugenol, offer a double benefit: Petition 870240108569, dated 12 / 19 / 2024, p. 8 / 28 3 / 21 Its analgesic properties provide relief for toothaches, while its antimicrobial qualities help fight oral infections (Al-Bayati et al., 2008). Mint, in addition to providing long-lasting freshness and a pleasant taste, has essential antibacterial properties to inhibit the growth of harmful bacteria in the oral cavity (Khan et al., 2012).

[008] The combination of these substances, when associated with the unique properties of cocoa, results in a toothpaste that not only promotes complete oral hygiene, but also improves gum health and fights infections with unprecedented effectiveness. This formulation is truly innovative, as it integrates the medicinal benefits and therapeutic properties of these natural ingredients synergistically, something not found in previous formulations. The result is a toothpaste that offers a holistic and natural approach to oral health, setting a new standard for effectiveness and innovation in dental care.

[009] Although the state of the art shows significant advances in the development of toothpastes with natural and medicinal ingredients, there are still important gaps in the effectiveness and scope of the solutions offered. (i) US8491920B2 TOOTHPASTE COMPRISING HERBAL EXTRACTS, describes a toothpaste containing extracts of various herbs, including chamomile, peppermint and sage extract, with anti-inflammatory, antimicrobial and soothing properties; (ii) EP 3175171 A1 HERBAL EXTRACT TOOTHPASTE, reports a toothpaste containing plant extracts, such as myrrh, chamomile, echinacea and oak bark, aimed at preventing oral diseases such as gingivitis and caries; (iii) CN103740771A TOOTHPASTE CONTAINING HERBAL EXTRACTS, describes a toothpaste formulation that uses green tea, chamomile and aloe vera extracts with antioxidant and antimicrobial benefits;(iv) WO2011090840 A1 TOOTHPASTE COMPRISING TEA TREE OIL AND OTHER HERBAL EXTRACTS, toothpaste containing tea tree oil, aloe vera extract and other herbal components, with antimicrobial and anti-inflammatory properties; (v) CN101973922B TOOTHPASTE WITH NEEM AND OTHER PLANT EXTRACTS, toothpaste containing neem extracts, in addition to other plant extracts such as mint and clove, intended for the treatment of oral infections and the promotion of gum health. According to the state of the art, most toothpaste formulations that use; Petition 870240108569, dated 12 / 19 / 2024, page 9 / 28 4 / 21 existing natural extracts, focuses on a limited number of benefits, such as preventing cavities, gingivitis, or combating bad breath, without holistically addressing the multiple needs of oral health.

[010] Another important issue is the underutilization of cocoa as a main ingredient in oral hygiene products. Despite the promising properties of theobromine and cocoa flavonoids in remineralizing tooth enamel and protecting against free radicals, few inventions fully exploit this potential. This leaves an opportunity for innovation that can efficiently combine cocoa with other natural ingredients, enhancing the benefits and overcoming the limitations of current products.

[011] Not only do the specific properties of cocoa contribute to the effectiveness of the invention, but also its interactions with other medicinal plants, which in synergy with cocoa, produce a potentiated therapeutic effect, namely:

[012] Cocoa (Theobroma cacao) and Chamomile (Matricaria chamomilla): Cocoa has antioxidant properties that can complement the anti-inflammatory effects of chamomile, enhancing the reduction of oral inflammation (Haskell et al., 2008).

[013] Cacao (Theobroma cacao) and Ginkgo biloba (Ginkgo biloba): Both have antioxidant properties. The combination may result in greater effectiveness in protecting against oxidative stress and improving gum health (Nicolle et al., 2003).

[014] Cocoa (Theobroma cacao) and Cinnamon (Cinnamomum cassia): While cocoa has anti-inflammatory properties, cinnamon is antimicrobial. Together, they can offer a synergistic effect in reducing inflammation and fighting oral bacteria (Ponnusamy et al., 2017).

[015] Cacao (Theobroma cacao) and Fennel (Foeniculum vulgare): Fennel promotes fresh breath, and cacao can help improve gum health, offering a combined benefit for overall oral health (Cheng et al., 2012).

[016] Other synergistic interactions between the plants in this formulation also contribute to the effectiveness of the invention, such as the reduction of inflammation. Petition 870240108569, dated 12 / 19 / 2024, page 10 / 28 5 / 21 enhanced by the combined effect of chamomile, sage, and cinnamon, which help reduce gingival inflammation, providing relief in conditions such as gingivitis and periodontitis (SRIVASTAVA et al., 2010; FIGUEIREDO et al., 2015); the antioxidant action created by the combination of cocoa and ginkgo biloba, protecting oral tissues from oxidative damage (CARRASCO-POZO et al., 2011; KOO et al., 2010); and also the mint-clove interaction that provides a refreshing effect and relieves oral discomfort, improving the overall user experience (WATANABE et al., 2003; TAPSELL et al., 2006). Solution Proposed by the Invention

[017] The present invention effectively solves these technical problems by presenting an innovative toothpaste that combines cocoa with a variety of medicinal plants, creating a multifunctional and natural formulation. This unique combination is not found in known products, offering several advantages compared to existing solutions. Differences and Advantages of the Invention

[018] The innovative formulation of this toothpaste goes beyond conventional solutions, comprehensively addressing multiple aspects of oral health. While most toothpastes are limited to a single benefit, such as cavity prevention, this exclusive formula combines ingredients with antimicrobial, anti-inflammatory, antioxidant, analgesic, and refreshing properties. Furthermore, it acts as a potent activator of blood circulation, intensifying the positive effects on oral health and overall well-being. The result is a complete solution that not only prevents cavities and combats bad breath, but also strengthens tooth enamel and promotes gum health, offering comprehensive protection for oral health.

[019] The invention comprehensively explores the properties of cocoa, especially highlighting its ability to remineralize tooth enamel and protect against oxidative damage. Unlike other formulations that may underestimate the benefits of cocoa, this toothpaste maximizes the use of the bioactive compounds present, such as theobromine and flavonoids. These components not only aid in the remineralization of tooth enamel, but Petition 870240108569, dated 12 / 19 / 2024, page 11 / 28 6 / 21 also offers significant antioxidant protection. Theobromine, for example, has shown potential in improving enamel hardness, while flavonoids possess antioxidant properties that combat damage caused by free radicals in the oral cavity (Carvalho et al., 2022; Monteiro et al., 2020). By providing a natural and effective alternative to traditional fluoride, this formulation offers an innovative approach to protecting and strengthening tooth enamel.

[020] Incorporation of Medicinal Plants in Synergy, with the combination of Ginkgo biloba, cinnamon, clove, and mint in the formulation, not only enhances the benefits of the toothpaste but also creates a powerful synergy between the ingredients, potentiating their therapeutic properties. Ginkgo biloba, known to improve blood circulation in the gums, contributes to periodontal health (Gao et al., 2021). Meanwhile, cinnamon and clove offer a strong antimicrobial action, effective against a wide range of oral bacteria (Nostro et al., 2004), and clove, rich in eugenol, fights infections and relieves toothaches (AlBayati et al., 2008). Mint not only provides a long-lasting and pleasant freshness but also plays an important role in inhibiting bacterial growth and reducing bad breath (Khan et al., 2012).This synergy between the ingredients enhances the therapeutic effects of the formulation, offering an innovative and effective approach to oral health. Absence of Menthol and Benefits of Xylitol

[021] The formulation of this toothpaste differs in the absence of menthol, common in traditional toothpastes, but which can be irritating for people with sensitive gums or mouth (Dawes, 2015). Instead, it uses natural mint and peppermint essential oil (Mentha piperita), which offers similar freshness without the risk of irritation (Cacace et al., 2021). The inclusion of xylitol, a sugar alcohol with anticariogenic properties, is another highlight. Xylitol not only inhibits the growth of cavity-causing bacteria, but also stimulates saliva production, aiding in enamel remineralization and maintaining gum health (Makinen, 2010). In addition to improving taste, xylitol reduces acid production by oral bacteria, preventing the formation of cavities, making this toothpaste a safe and effective alternative, especially in the absence of fluoride. Petition 870240108569, dated 12 / 19 / 2024, page 12 / 28 7 / 21 Brushing experience and holistic approach

[022] In addition to its effectiveness in promoting oral health, the combination of medicinal plants in this formulation provides a brushing experience that is both pleasant and effective. The absence of fluoride in the formulation is a deliberate choice, aiming to address contemporary concerns about fluoride use, which include potential adverse effects at high concentrations and concerns about dental fluorosis (Konig et al., 2017). Instead, the toothpaste leverages the beneficial properties of medicinal plants such as Ginkgo biloba, cinnamon, clove, and mint, offering a holistic approach to dental hygiene. These plants not only contribute to gum health and control of oral bacteria but also ensure high-quality oral care, aligned with modern needs and concerns about oral health (Maddox et al., 2020; Lima et al., 2022).The formulation is designed to reduce the risks associated with fluoride and provide additional therapeutic benefits, promoting a safer brushing experience that meets current consumer expectations. Innovative Solution for Oral Health Challenges

[023] The present invention represents an innovative and effective solution to the challenges not yet fully resolved by toothpaste formulations available on the market. Differing from traditional formulations, which frequently use fluoride and other synthetic compounds, this toothpaste is composed of carefully selected natural ingredients, such as cocoa and medicinal plants, including Ginkgo biloba, cinnamon, clove, and mint. Each of these components brings specific properties that contribute to comprehensive oral health. Cocoa, for example, is known for its antioxidant properties and enamel remineralization potential (Carvalho et al., 2022). Ginkgo biloba improves blood circulation in the gums and has antioxidant properties (Gao et al., 2021). Cinnamon and clove offer antimicrobial and anti-inflammatory actions that combat oral bacteria and relieve inflammation (Nostro et al., 2004; Al-Bayati et al., 2008).Mint provides a refreshing sensation and helps control bad breath, in addition to having antibacterial properties (Khan et al., 2012). Together, these properties allow the formulation to offer a... Petition 870240108569, dated 12 / 19 / 2024, page 13 / 28 8 / 21 offers a holistic and natural approach to oral health, overcoming the limitations of conventional toothpastes.

[024] The absence of fluoride is a significant differentiating factor of this invention, especially in a context where there are growing concerns about the possible adverse effects of fluoride, such as dental fluorosis and other impacts associated with its overexposure (Fung et al., 2021). Dental fluorosis is a condition that can occur due to excessive fluoride consumption during tooth development, resulting in staining and damage to the enamel (Huang et al., 2019). By opting for a fluoride-free formula, this invention offers a safe and natural alternative that meets the growing demand for healthier and more environmentally friendly products.

[25] The formulation combines natural ingredients with proven therapeutic properties, such as the antioxidant and antimicrobial compounds of cocoa and medicinal plants, providing a complete and balanced approach to oral health (Carvalho et al., 2022; Maddox et al., 2020). This approach not only responds to the need for safer and more sustainable alternatives, but also maintains effectiveness in combating common oral problems such as cavities and gingivitis. Furthermore, it aligns with contemporary trends of conscious consumption, offering a solution that is both effective and ecologically responsible.

[026] This invention stands out for its use of natural ingredients and the exclusion of harmful synthetic compounds, offering a safe solution for consumers and a sustainable solution for the environment. In line with the growing demand for ecological and healthy products, the formula aligns with contemporary trends of conscious consumption (Smith et al., 2020).

[027] This combination of cocoa and medicinal plants not only meets oral health needs but also offers remineralizing, antimicrobial, and antioxidant properties (Carvalho et al., 2022; Gao et al., 2021). These ingredients provide an effective approach to oral hygiene, improving gum health, fighting harmful bacteria, and preventing inflammation. Furthermore, the use of natural ingredients minimizes environmental impact, promoting an oral hygiene solution that is both effective and ecologically responsible (Johnson et al., 2019). Although the absence of fluoride is an aspect Petition 870240108569, dated 12 / 19 / 2024, page 14 / 28 9 / 21 relevant to the formulation, the real difference lies in the synergy of the natural components, which together offer comprehensive benefits for oral health, without the risks associated with the prolonged use of synthetic compounds (Molina-Frechero et al., 2019).

[028] The absence of menthol and fluoride in this toothpaste formulation offers a safe solution for children and individuals with increased oral sensitivity. Although menthol is widely used in commercial toothpastes for its ability to provide a feeling of freshness, it can cause irritation to the oral mucosa, especially in children and people with sensitive gums (Cacace et al., 2021). In addition, overexposure to fluoride has been associated with other adverse health effects, which increases the need for safe alternatives for vulnerable groups (Fung et al., 2021). The Brazilian population already receives the necessary amount of fluoride in the fluoridated water supplied by the water supply, while an excess of this element increases the risk of dental fluorosis and is also associated with other undesirable health conditions.The absence of these elements (fluoride and menthol) in our formulation makes this toothpaste a safe option for both children and adults, including those with specific sensitivities. By using natural ingredients such as xylitol and peppermint essential oil, the formulation provides the essential benefits of oral hygiene, such as preventing cavities and maintaining gum health, without the risks associated with menthol and fluoride (Mãkinen, 2010; Lenoir-Wijnkoop et al., 2021). Therefore, this toothpaste is not only effective but also represents a safe choice for the whole family, meeting oral care needs in a gentle and natural way.

[029] The innovative formulation proposed in this study effectively solves a technical problem not fully addressed by existing toothpastes on the market. Differing from traditional formulations, which frequently use fluoride and synthetic compounds, this toothpaste combines the natural power of cocoa with medicinal plants such as Ginkgo biloba, cinnamon, clove, and mint. The synergy between these ingredients offers a natural and sustainable solution for oral health, enhancing antimicrobial, anti-inflammatory, antioxidant, and refreshing properties. Undoubtedly, the absence of fluoride, an ingredient... Petition 870240108569, dated 12 / 19 / 2024, page 15 / 28 The controversial 10 / 21 formula, replaced by natural ingredients with remineralizing and antimicrobial properties, such as xylitol, ensures a safe and effective alternative for preventing cavities and promoting gum health. This makes this toothpaste unique by replacing all potentially harmful ingredients with medicinal plants that promote oral health. This feature is especially relevant in a context where there are growing concerns about the long-term adverse effects of fluoride.

[030] Furthermore, the formula excludes menthol, a common ingredient in toothpastes that, despite providing a refreshing sensation, can cause irritation in individuals with oral sensitivity. Instead, natural mint and mint essential oil are used to ensure freshness and comfort during brushing, without the risk of irritation, making the toothpaste safe for the whole family, including children and people with increased sensitivity. Therefore, this invention not only promotes comprehensive and effective oral health, but also aligns with contemporary trends of conscious consumption, offering a solution that is simultaneously natural, sustainable, and environmentally responsible. The combination of carefully selected natural ingredients sets a new standard of quality in oral hygiene, providing proven benefits that meet the needs of modern consumers concerned about health and the environment. Description of the Invention

[031] This is an innovative toothpaste, developed from plant-based ingredients, especially cocoa, without the addition of fluoride. This formulation combines a variety of medicinal plants carefully selected for their proven beneficial properties for oral health. By replacing fluoride with natural alternatives, the invention offers a safe and effective solution for oral hygiene, meeting the needs of both children and adults. In addition to promoting the cleaning and protection of teeth and gums, the formulation aims to prevent dental problems naturally, providing a healthier and more sustainable approach compared to conventional toothpastes that use synthetic compounds. Petition 870240108569, dated 12 / 19 / 2024, page 16 / 28 11 / 21 Description of the Implementation of the Invention

[032] Toothpaste formulated from an innovative combination of cocoa powder and various medicinal plants, replacing traditional synthetic abrasives such as silica and calcium carbonate. Cocoa powder is chosen as the main active ingredient due to its physical properties suitable for tooth brushing, in addition to its remarkable anti-inflammatory and blood vessel strengthening qualities.

[033] The preferred toothpaste formulation is composed of the following main ingredients: (i) cocoa powder which acts as a mild abrasive and offers physical properties suitable for dental cleaning and anti-inflammatory and vaso-protective benefits; (ii) dried and ground medicinal plants in ultrafine particles, including bay leaf (Laurus nobilis), whose natural compounds, such as cineole and eugenol, help inhibit bacterial growth, promoting a healthier mouth and also have anti-inflammatory, antioxidant action and combat bad breath; Ginkgo biloba rich in flavonoids and terpenoids such as ginkgolides and bilobalides, improves blood circulation, promoting better oxygenation, tissue nutrition, which is particularly appropriate for oral health, in the regeneration of inflammations or lesions and in the control of periodontal diseases;Turmeric (Curcuma longa), rich in curcumin, has anti-inflammatory, antimicrobial, and antioxidant properties, components that help reduce gingival inflammation, fight oral bacteria, and protect oral tissues from damage; Cardamom (Elettaria cardamomum) contains cineole, terpineol, and limonene, with antimicrobial, anti-inflammatory, and antioxidant properties, components that help fight bacteria that cause bad breath, reduce inflammation in the oral cavity, and protect oral tissues; Fennel (Foeniculum vulgare), rich in anethole and fenchone, with antimicrobial and anti-inflammatory properties, components that help fight bacteria in the mouth, promoting fresh and healthy breath, and reducing gingival inflammation; Cinnamon (Cinnamomum cassia) is known for its antimicrobial and anti-inflammatory properties, containing active compounds such as cinnamaldehyde, which is responsible for its antimicrobial and anti-inflammatory actions.Clove (Syzygium aromaticum) has antibacterial and analgesic properties, thanks to eugenol, which fights oral bacteria and relieves pain. Petition 870240108569, dated 12 / 19 / 2024, page 17 / 28 12 / 21 contributing to the relief of oral discomfort; chamomile (Matricaria chamomilla), known for its anti-inflammatory and soothing properties attributed to its flavonoids and essential oil, helps reduce gingival inflammation and relieve oral discomfort; sage (Salvia officinalis) contains compounds such as rosmarinic acid and cineole, which have antimicrobial and anti-inflammatory properties, helping to fight oral bacteria and reduce gingival inflammation. These ingredients were selected for their antimicrobial, anti-inflammatory, and antioxidant properties, contributing to comprehensive oral health.

[034] In addition to the main active ingredients, the formulation includes (i) calcium carbonate and sodium bicarbonate, used as mild abrasives and alkalizing agents, helping to cleanse and balance the pH of the mouth; (ii) glycerinated plant extracts that contribute to the consistency and preservation of the paste; chamomile extract, with anti-inflammatory and soothing properties, relieves oral irritations and inflammations, while its antioxidants protect against oxidative stress; sage extract, in turn, offers antimicrobial actions that combat bacteria and fungi, in addition to its astringent effect, which tones the oral tissues. These extracts, together, increase the effectiveness of the product, promoting oral health and freshness, as well as improving the preservation of the formulation; (iii) xanthan gum, a natural thickener that ensures the proper texture of the paste;(iv) Xylitol is a natural sweetener that improves the taste of the toothpaste and has anti-cariogenic properties; it reduces the amount of cariogenic bacteria in the mouth and promotes dental health by decreasing the formation of cavities, in addition to having a remineralizing action for the teeth; (v) Peppermint essential oil adds refreshing and bactericidal properties, as well as contributing to a pleasant taste; (vi) Propolis has antibacterial, antifungal, and anti-inflammatory properties, combats bacteria that cause cavities and gum disease, accelerates the healing of oral tissues and strengthens the gums; its antiseptic action also helps eliminate bad breath and acts as a natural preservative, prolonging the shelf life of the toothpaste by inhibiting the growth of microorganisms, which improves its durability.

[035] The innovation of this invention lies in the replacement of chemical and synthetic additives with natural components, resulting in a product that not only cleans Petition 870240108569, dated 12 / 19 / 2024, page 18 / 28 13 / 21 and protects teeth, but also promotes overall oral health in a natural and safe way. The absence of fluoride caters to consumers concerned about the potential adverse effects of fluoride, while the use of cocoa as an abrasive agent offers a unique sensory experience, ideal for those seeking more natural and less aggressive alternatives for oral hygiene. Preparation and Formulation Method Example of implementation 1: Acquisition and handling of materials

[036] The plants were acquired at the city's municipal market, through small-scale farmers. They were purchased dried to be taken to the beginning of the processing. The plants and parts are listed below: Cocoa (Theobroma cacao) - Almonds (seeds) powder; Bay leaf (Laurus nobilis) leaves; Ginkgo biloba - roots (powder); Turmeric (Curcuma longa) - roots (powder); Cardamom (Elettaha cardamomum) - seeds (powder); Anise (Pimpinella anisum) - seeds (powder); Cinnamon (Cinnamomum cassia) - bark powder; Clove (Syzygium aromaticum) - dried flower buds; Chamomile (Matricaria chamomilla) - flowers; Sage (Salvia officinalis) - leaves.

[037] The chemical materials used, such as calcium carbonate, sodium bicarbonate, xylitol, xanthan gum and glycerin, were purchased from the company Cientifica S / A, found on the website https: / / cientificalab.com.br / , all under the brand name Êxodo Cientifica.

[038] Green propolis is purchased from local producers from family farms at the municipal market in the city of Ilhéus, in 50g bags. The entire contents of the bag (50g) are used to make 500g (500ml) of hydroalcoholic propolis extract to be used later in the formulation of toothpaste. The following procedure is adopted: In a glass container, 450g of 70% alcohol commercially sold by Cientifica S / A (https: / / cientificalab.com.br / ) is added, 50g of green propolis is weighed and added to the alcohol. It is left to macerate for 45 days, manually shaking the bottle every 2 days to aid in the extraction process of the components by the hydroalcoholic mixture. After the time has elapsed, the mixture is filtered through a 150mm qualitative filter acquired commercially, also from Científica S / A. Petition 870240108569, dated 12 / 19 / 2024, page 19 / 28 14 / 21 Example of implementation 2: Obtaining toothpaste

[039] The following preparation manipulation / formulation process was used:

[040] Plant weighing: all acquired plant material was carefully weighed and ground separately until it reached a fine particle size of 0.5 mm, obtaining an extremely fine powder. This process optimizes the mixing performance, improving the homogeneity of the components and facilitating the integration of the active ingredients in formulations. The smaller particle size increases the contact surface, promoting a more uniform and effective distribution of the active ingredients in the final mixture. In addition, the fine powder improves solubility and dispersion, ensuring greater consistency in the product and greater control over the release of bioactive compounds.

[041] Mixture of crushed vegetables.

[042] Weigh 250g of cocoa and place it in a stainless steel container where the plants will be added. Weigh 20g of bay leaf, 10g of Ginkgo biloba, 10g of turmeric, 10g of cardamom, 30g of fennel, 30g of cinnamon, 25g of cloves, and 10g of sage. The weighed plant materials, after being crushed, are added to the cocoa powder. Weigh the abrasive agents: calcium carbonate (150g) and sodium bicarbonate (80g) and add them to the formula. Weigh 20g of xanthan gum and add it to 170g of vegetable glycerin (Êxodo Cientifica), separately, stirring and letting it stand for 10 minutes for proper dilution. Weigh 80g of xylitol and add it to the dry powders. Weigh 10g of glycerinated sage extract and add it to the vegetable glycerin and xanthan gum that are set aside. After complete dissolution, add it to the powders (plants and abrasive agents), mixing well. Measure the pH, which should be between 6.8 and 8.0.If necessary, the pH of the formula should be adjusted using citric acid to lower the pH or increasing the amount of calcium carbonate to raise the pH. In this case, it was not necessary. The pH was 7.2. Weigh 20g of peppermint essential oil and add it to the formula. Mix the entire mixture at 2000 rpm for 6 minutes until a homogeneous mixture is obtained. Adjustments and Quality Control: Evaluate the consistency of the paste. If necessary, adjust the amount of xanthan gum to ensure adequate viscosity. Check the pH of the formula again to ensure that the formulation's pH is in the range of 6.8 to 8.0, guaranteeing that the paste is... Petition 870240108569, dated 12 / 19 / 2024, page 20 / 28 15 / 21 Gentle on tooth enamel, yet effective in cleaning the oral cavity. Package the final product in tubes.

[043] As per embodiment example 2, the resulting composition is shown in table 1 below. Table 1: Composition A for toothpastes made with cocoa and medicinal plants Component Quantity (g) Cocoa powder 250 Bay leaf 20 Ginkgo biloba 10 Turmeric 10 Cardamom 10 Fennel 30 Cinnamon 30 Cloves 25 Chamomile 0 Sage 10 Calcium carbonate 150 Sodium bicarbonate 80 Glycerinated chamomile extract 50 Glycerinated sage extract 30 Glycerin 170 Xanthan gum 20 Xylitol 80 Petition 870240108569, dated 12 / 19 / 2024, page 21 / 28 16 / 21 Peppermint essential oil 20 Propolis 0 Table 2: Composition B for cocoa and medicinal plant toothpastes Component Quantity (g) Cocoa powder 250 Bay leaf 45 Ginkgo biloba 35 Turmeric 25 Cardamom 10 Fennel 10 Cinnamon 18 Cloves 12 Chamomile 10 Sage 30 Calcium carbonate 100 Sodium bicarbonate 40 Glycerinated chamomile extract 30 Glycerinated sage extract 30 Glycerin 250 Xanthan gum 20 Xylitol 50 Peppermint essential oil 13 Petition 870240108569, dated 12 / 19 / 2024, page 22 / 28 17 / 21 Propolis Table 3: Composition C for cocoa and medicinal plant toothpaste Component Quantity (g) Cocoa powder 200 Bay leaf 50 Ginkgo biloba 30 Turmeric 30 Cardamom 30 Fennel 25 Cinnamon 30 Cloves 30 Chamomile 20 Sage 26 Calcium carbonate 135 Sodium bicarbonate 55 Glycerinated chamomile extract 0 Glycerinated sage extract 0 Glycerin 250 Xanthan gum 20 Xylitol 50 Peppermint essential oil 10 Propolis 10 Petition 870240108569, dated 12 / 19 / 2024, pp. 23 / 28 18 / 21 Table 4: Composition D for cocoa and medicinal plant toothpastes Component Quantity (g) Cocoa powder 300 Bay leaf 45 Ginkgo biloba 35 Turmeric 10 Cardamom 20 Fennel 25 Cinnamon 30 Cloves 25 Chamomile 20 Sage 20 Calcium carbonate 100 Sodium bicarbonate 30 Glycerinated chamomile extract 0 Glycerinated sage extract 0 Glycerin 250 Xanthan gum 20 Xylitol 50 Peppermint essential oil 10 Propolis 10 Petition 870240108569, dated 12 / 19 / 2024, pages 24 / 28 19 / 21

[044] In summary, considering formulations A, B, C, and D, the toothpastes prepared in this invention have the following composition range (Table 5): Cocoa powder (Theobroma cacao) 20-30% Bay leaf (Laurus nobilis) 2-5% Ginkgo biloba 1-3.5% Turmeric (Curcuma longa) 1-3% Cardamom (Elettaria cardamomum) 1-3% Anise (Pinpinella anisum) 1-3% Cinnamon (Cinnamomum cassia) 1-3% Clove (Syzygium aromaticum) 1-3% Chamomile (Matricaria chamomilla) 1-3% Sage (Salvia officinalis) 1-3% Calcium carbonate 10-15% Sodium bicarbonate 5-8% Glycerinated chamomile extract 0-5% Petition 870240108569, dated 12 / 19 / 2024, pages 25 / 28 20 / 21 Glycerinated sage extract 0-5%, Glycerin 5-25%, Xanthan gum 2-3%, Xylitol 5-8%, Peppermint essential oil 0.8-2%, Propolis 1-2% Possibilities for Implementation

[045] Toothpaste can be adapted to different presentation forms, such as tubes, sachets, or packaging of different sizes, to meet diverse market needs. In addition, the formula can be adjusted to include other natural ingredients or adjustments to the concentration of extracts, as needed to meet new scientific discoveries or consumer preferences.

[046] The proposed toothpaste represents a significant innovation by integrating a range of natural ingredients known for their oral health benefits into an effective formula. The combination of cocoa with various medicinal plants and additives offers a healthy and efficient alternative to conventional products, aligning with market trends seeking natural and sustainable solutions. The absence of fluoride is an added advantage, providing a safer option, especially for children, while the plant-based ingredients offer comparable and even superior oral health benefits. Economic feasibility study Petition 870240108569, dated 12 / 19 / 2024, pages 26 / 28 21 / 21

[047] To make 1 kg of paste D you need 300 g Cocoa powder, 45 g Bay leaf, 35 g Ginkgo biloba, 10 g Turmeric, 20 g Cardamom, 25 g Fennel, 30 g Cinnamon, 25 g Cloves, 20 g Chamomile, 20 g Sage, 100 g Calcium carbonate, 30 g Sodium bicarbonate, 250 g Glycerin, 20 g Xanthan gum, 50 g Xylitol, 10 g Peppermint essential oil.

[048] To create this, an average of R$145.00 (one hundred and forty-five reais) was spent. Packaged in standard 60g containers on the market, there will be approximately 16 60g tubes. In this case, the production cost per 60g tube is R$9.00. In addition to the production cost, there is the cost of the tube, label and other materials, transport, storage, etc., advertising costs and profit margin. The suggested selling price will be based on the following calculation: Production cost (R$ 8.76); Additional cost (R$ 3.00) Total: R$8.76 + R$3.00 = R$11.76 Adding a 50% profit margin: R$11.76 + R$5.88 = R$17.64.

[049] This value is below that practiced among natural toothpastes sold on the market. These values ​​are currently varying between R$ 23.00 and R$ 90.00 for natural, fluoride-free products, with proposals similar to the present invention. However, despite containing natural extracts, they do not have more than 20% natural extracts in their composition, while ours has at least 50% plant extracts. Petition 870240108569, dated 12 / 19 / 2024, pp. 27 / 28

Claims

1 / 2 CLAIMS 1. HERBAL TOOTHPASTE characterized by comprising cocoa powder (Theobroma cacao), bay leaf (Laurus nobilis), ginkgo biloba (Ginkgo biloba), turmeric (Curcuma longa), cardamom (Elettaria cardamomum), fennel (Foeniculum vulgare), cinnamon (Cinnamomum cassia), clove (Syzygium aromaticum), chamomile (Matricaria chamomilla), sage (Salvia officinalis), calcium carbonate, sodium bicarbonate, glycerinated extract of chamomile, glycerinated extract of sage, xanthan gum, xylitol, peppermint essential oil, propolis.

2. TOOTHPASTE BASED ON MEDICINAL PLANTS characterized by containing cocoa powder (Theobroma cacao) (20% to 30%); bay leaf (Laurus nobilis) (2% to 5%); ginkgo biloba (Ginkgo biloba) (1% to 3.5%); turmeric (Curcuma longa) (1% to 3%); cardamom (Elettaria cardamomum) (1% to 3%); fennel (Foeniculum vulgare) (1% to 3%); cinnamon (Cinnamomum cassia) (1% to 3%); cloves (Syzygium aromaticum) (1% to 3%); chamomile (Matricaria chamomilla) (1% to 3%); sage (Salvia officinalis) (1% to 3%); calcium carbonate (5% to 15%); Sodium bicarbonate (5% to 8%); glycerinated chamomile extract (0% to 5%); glycerinated sage extract (0% to 5%); xanthan gum (2% to 3%); xylitol (5% to 8%); peppermint essential oil (0.8% to 2%); propolis (1% to 2%).

3. HERBAL TOOTHPASTE characterized by containing 25% cocoa, 2% bay leaf, 1% Ginkgo biloba, 1% turmeric, 1% cardamom, 3% fennel, 3% cinnamon, 2.5% cloves, 1% sage, 15% calcium carbonate, 8% sodium bicarbonate, 2% xanthan gum, 17% vegetable glycerin, 8% xylitol, 1% glycerinated sage extract, 2% peppermint essential oil.

4. PROCESS FOR PREPARING TOOTHPASTE BASED ON MEDICINAL PLANTS characterized by having the following steps: separation and grinding of the plant material (leaves, flowers, stems and roots), weighing of the plant material, joining and mixing of all the powdered plant materials, weighing of the abrasive agents, weighing of the glycerin, weighing of the plant extracts, dissolving the xanthan gum in the glycerin, joining of the solution (vegetable glycerin + xanthan gum) with the glycerinated extract (liquid phase), joining of the powder phase with the liquid phase, mixing and homogenization, pH measurement, addition of the essential oil, pH measurement and adjustment, and packaging.

5. Use of the medicinal plants cocoa powder (Theobroma cacao), bay leaf (Laurus nobilis), ginkgo biloba (Ginkgo biloba), turmeric (Curcuma longa), cardamom (Elettaria cardamomum), fennel (Foeniculum vulgare), cinnamon (Cinnamomum cassia), clove (Syzygium aromaticum), chamomile (Matricaria chamomilla) and sage (Salvia officinalis) characterized by being for the preparation of a toothpaste for the treatment of gingivitis.

6. Use of medicinal plants characterized by including cocoa powder (Theobroma cacao), bay leaf (Laurus nobilis), ginkgo biloba (Ginkgo biloba), turmeric (Curcuma longa), cardamom (Elettaria cardamomum), fennel (Foeniculum vulgare), cinnamon (Cinnamomum cassia), clove (Syzygium aromaticum), chamomile (Matricaria chamomilla) and sage (Salvia officinalis). Petition 870240108569, dated 12 / 19 / 2024, page 6 / 28