Composition for skin treatment

Abstract

SUMMARY “SKIN TREATMENT COMPOSITION” The compositions and methods of the present invention relate to a skin treatment composition to be left on the application surface containing hydrophobic linear cellulose particles having an average length of about 1 to about 500 µm, a particle aspect ratio of about 2 to about 25 and an average thickness of about 1 to about 500 µm; and a cosmetically acceptable vehicle.

Description

1 / 35 “SKIN TREATMENT COMPOSITION”

[0001] This application is a continuation-in-part of U.S. Application 13 / 673,430 filed on November 9, 2012, the full disclosure of which is hereby incorporated by reference for all purposes. Field of invention

[0002] The compositions of the present invention relate to skin treatment compositions to be left on the application surface containing hydrophobic linear cellulose particles that reduce the presence of oil-related substances on the skin. Background of the invention

[0003] Oily skin is shiny, thick, and dull in color. Chronically oily skin often has large pores and is prone to pimples and other embarrassing blemishes. Additionally, chronically oily skin can be prone to developing blackheads. In this skin type, the sebaceous glands that produce oil are overactive and produce more oil than is needed. The oil flows out of the follicles and gives the skin an undesirable greasy shine. The pores are enlarged, and the skin has a coarse appearance. While oily skin is common in teenagers, it can occur at any age.

[0004] In general, individuals with oily skin try to treat areas of oiliness to prevent acne breakouts and reduce shine. Conventional treatments available include soaps or cleansing creams based on surfactants, astringents with alcohol, and mud or clay masks. Oil-absorbing materials such as clay or salt have also been used to try to treat this condition.

[0005] Individuals who have shiny skin conditions or Petition 870260055635, dated 09 / 06 / 2026, page 8 / 46 2 / 35 of people with oily skin prefer a treatment that can remove shine without drying out their skin. However, there is a lack of effective skincare products on the market today that address this consumer need. Oil-absorbing powders such as silica, aluminum starch, and talc have been used in cleansing products to help dry out surface oil, but these also tend to dry out the skin, and oiliness and shine tend to return quickly, usually within two to three hours.

[0006] Therefore, it would be desirable to have compositions and treatment methods that address the condition of oily skin while simultaneously keeping the skin hydrated. Summary of the invention

[0007] The compositions and methods of the present invention relate to a skin treatment composition to be left on the application surface, comprising linear, hydrophobic cellulose particles having an average length of about 1 to about 500 µm, a particle aspect ratio of about 2 to about 25 and an average thickness of about 1 to about 500 µm; and a cosmetically acceptable vehicle. Description of the drawings

[0008] Figure 1 is a graph of infrared spectra of various cotton and cellulose particles;

[0009] Figure 2 is a graph of infrared spectra of various solvent extracts from hydrophobic cotton particles and dimethicone;

[0010] Figure 3 is a graph illustrating oil absorption rates of hydrophilic and hydrophobic cotton particles;

[0011] Figure 4 is a graph of the absorption rate. Petition 870260055635, dated 09 / 06 / 2026, page 9 / 46 3 / 35 of water measured from various hydrophobic and hydrophilic cotton particles;

[0012] Figure 5 is a graph illustrating the average oil absorption capacity of various hydrophobic and hydrophilic cotton particles;

[0013] Figure 6 is a graph illustrating the average water absorption capacity of various hydrophobic and hydrophilic cotton particles; and

[0014] Figure 7 is a graph illustrating the reduction of sebum in skin exposed to various leave-in conditioner compositions of the present invention. Detailed description of preferred embodiments: Linear, hydrophobic cellulose particles

[0015] As used herein, the term hydrophobic means materials that have a surface contact angle with squalene less than 40 degrees and / or a surface contact angle with water greater than 90 degrees. The term surface contact angle means the internal angle between a surface and a liquid droplet deposited on that surface. Surface tension (liquid) or surface free energy (solid) is considered to be a resulting equilibrium between the molecular interactions of the liquid-liquid and air-liquid or solid-solid and air-solid phases in the interfacial layer. The term contact angle is a useful and convenient parameter for determining the surface free energy and wettability of any given solid surface due to the non-deformability of the solid. The contact angle is determined by measuring the angle formed between the surface of the substrate where a liquid droplet is placed and the tangent to the droplet surface. Petition 870260055635, dated 09 / 06 / 2026, page 10 / 46 4 / 35 from the point of contact. High contact angles correspond to poor wettability of the surface by the liquid, and low contact angles mean good wettability. If a liquid spreads on the surface, the contact angle is considered to be zero, and complete wettability is said to occur.

[0016] Contact angle measurements can be made to determine the wettability of human skin by a variety of liquids, including hydrophobic liquids such as squalene, and hydrophilic liquids, including water. A smaller contact angle with a nonpolar liquid (such as squalene) corresponds to a more hydrophobic material, while a smaller contact angle with water corresponds to a more hydrophilic material.

[0017] According to the methods and compositions of the present invention, the water contact angle of the hydrophobic linear cellulose particles is preferably greater than 90 degrees, preferably greater than 100 degrees, and most preferably greater than 120 degrees.

[0018] As used herein, the term oil absorption and retention capacity refers to the percentage, by weight, of oil absorbed by the hydrophobic linear cellulose particles useful in the compositions and methods of the present invention. High oil absorption and retention capacity corresponds to an increased hydrophobic property. The oil absorption and retention capacity of the hydrophobic linear cellulose particles of the compositions of the present invention is preferably from about 150 to about 500, and more preferably from about 300 to about 500 (% oil weight / particle weight). Petition 870260055635, dated 09 / 06 / 2026, page 11 / 46 5 / 35

[0019] As used herein, the term particle means a small, localized object to which physical properties such as volume or mass can be attributed. As used herein, dust is used as a synonym for particle, as defined herein.

[0020] As used herein, the term linear particle means a particle having one dimension (length) that is larger than another dimension (width). Linear particles can be measured and defined by size by subjecting such particles to analysis with a series of sieves with meshes of different sizes. In general, a sample of linear particles may have a particle size distribution throughout the sample. Thus, the particle sizes as expressed herein are expressed as an average particle size and reflect the average length of the particles contained in the sample.

[0021] Preferably, the size of useful linear particles in the compositions and methods of the present invention is less than about 500 µm in length, more preferably in the range of about 2 to about 500 µm, and most preferably from about 10 to about 300 µm. The preferred width of useful linear particles in the compositions and methods of the present invention is about 1 to about 25 µm. More preferably, they are about 1 to about 20 µm wide.

[0022] As used herein, the term particle aspect ratio means the ratio between the length of a particle and its width. Preferably, the particle aspect ratio of the particles useful in the compositions and methods of the present invention is from about 2 to about 20. With more Petition 870260055635, dated 09 / 06 / 2026, p. 12 / 46 6 / 35 preference, the particle ratio is from about 2 to about 15 and with maximum preference, from about 2 to about 10.

[0023] As used herein, the term “cellulose” refers to a polysaccharide material consisting of long, unbranched chains of linked glucose units, having the chemical structure shown in Formula I below: The Earth's surface has provided humanity with functional, low-cost, and renewable raw materials.

[0025] The cellulose materials useful in the compositions and methods of the present invention may be derived from cotton, corn, wood pulp and bamboo pulp, silk, cork and the like. Preferably, the cellulose materials useful in the compositions of the present invention are derived from cotton. More preferably, the cellulosic particles are from fibers recovered from post-industrial waste. Such waste is derived from residue or other pre-consumer cotton products from, for example, the clothing, carpet, furniture and household goods industries. Synthetic or regenerated cellulose or cotton materials may also be used as sources for the cellulose particles useful in the compositions and methods of the present invention, including rayon, viscose, cellophane, and other cellulosic materials with a reproducible uniform molecular distribution and size. Petition 870260055635, dated 09 / 06 / 2026, page 13 / 46 7 / 35

[0026] The cellulose materials useful in the compositions and methods of the present invention may be derived directly from the source plant (referred to herein as raw particles) or may be generated from previously formed nonwoven or cloth materials of cellulose or plant fibers (referred to herein as regenerated particles). For example, cotton cloth may be processed so as to break the cloth into small particles and / or uniform fiber length by cutting the length of the cotton fibers from inches to microns. This randomly cut fiber is available in various types, white, dark and unbleached, with average fiber lengths of about 1 micron to about 500 microns and preferably from about 2 microns to about 300 microns.

[0027] Typical mechanical grinding processes such as those useful in cutting the size of cellulose materials useful in the compositions and methods of the present invention, for example, are described in US Patent No. 7594619 and US Patent No. 6656487, which are hereby incorporated by reference.

[0028] In general, the cellulose particles useful in the compositions of the present invention can be processed according to the following methods:

[0029] A method comprises mixing a cellulosic material derived from waste, as defined above, with at least one of the auxiliary grinding media selected from the group that includes water, fatty acids, synthetic polymers and organic solvents and, after mixing, mechanical grinding of the mixture.

[0030] Another method of obtaining cellulose particles is to freeze a cellulosic material derived from post-Petition 870260055635, dated 09 / 06 / 2026, page 14 / 46 8 / 35 industrial at a low temperature and then mechanically crush said frozen material. The cellulose particles useful in the compositions and methods of the present invention may be further treated with hydrophobic agents to produce hydrophobic cellulose particles. For example, a hydrophobic coating agent may be used to treat the cellulose particles. The hydrophobic coating agent may be any agent known to those skilled in the art. Preferred hydrophobic coating agents react chemically with the cellulose particles to provide a durable covalent bond with them and have hydrophobic chemical back chains or substituents that can provide a hydrophobic outer layer around each individual cellulose particle. The coating agent may react, for example, with hydroxyl groups, available oxygen atoms present on the surface of the cellulose particle being coated.

[0031] Hydrophobic agents may include, but are not limited to, low-soluble, water-soluble organic compounds, such as metallic soap, for example, a metal myristate, metal stearate, a metal palmitate, a metal laurate, or other fatty acid derivatives known to a person skilled in the art. Other hydrophobic agents may include an organic wax, such as a synthetic wax like polyethylene or a natural wax like carnauba wax. Hydrophobic agents useful in coating the cellulose particles useful in the compositions and methods of the present invention may also be long-chain fatty acids or esters such as stearic acid, oleic acid, castor oil, Petition 870260055635, dated 09 / 06 / 2026, page 15 / 46 9 / 35 Isododecane, silicone, and its derivatives, water-insoluble polymers, for example, high molecular weight methylcellulose and ethylcellulose, and high molecular weight water-insoluble fluoropolymers, etc., siloxanes or polysiloxanes polymerized with the chemical formula [R2SiO]n, wherein R is an organic group such as methyl, ethyl, or phenyl, such as dimethicone, dimethicone copolyol, dimethicone ester; methicone and its derivatives. Examples of hydrophobic linear cotton particles useful in the present invention include, but are not limited to, Cotton Fiber Flock CD60 available from Goonvean Fiber and W200 White Cotton Flock available from International Fiber Corporation.

[0032] The hydrophobic linear cellulose particles of the present invention can be formulated in a variety of leave-on skin treatment applications on the application surface.

[0033] The term "to be left on the application surface" as used herein indicates that the compositions of the present invention are intended to be applied to and left on the skin. These compositions to be left on the application surface should be distinguished from compositions that are applied to the skin and subsequently removed by washing, rinsing, scrubbing, or the like.

[0034] The compositions containing linear, hydrophobic cellulose particles for leave-on application of the present invention can be formulated in a wide variety of leave-on application compositions for personal care including, but not limited to, lotions, creams, ointments, gels, Petition 870260055635, dated 09 / 06 / 2026, page 16 / 46 10 / 35 tonics, dispersions, aerosols, conditioners, hand and body lotions, facial moisturizers, solid sticks, sunscreens, anti-acne preparations, topical analgesics, masks, makeup, antiperspirants and deodorants.

[0035] The topical cosmetic compositions of the present invention may contain a vehicle, which must be a cosmetically and / or pharmaceutically acceptable vehicle. The vehicle must be suitable for topical use on the skin, must have good aesthetic properties and must be compatible with other components in the composition.

[0036] These product types may comprise various types of cosmetically acceptable topical vehicles including, but not limited to, solutions, emulsions (e.g., microemulsions and nanoemulsions), gels, solids, and liposomes. The following are non-limiting examples of such vehicles. Other vehicles may be formulated by those skilled in the art.

[0037] Useful topical compositions according to the present invention can be formulated as solutions. Solutions typically include an aqueous solvent (e.g., from about 50% to about 99.99% by weight or from about 90% to about 99% by weight of a cosmetically acceptable aqueous solvent).

[0038] Topical compositions useful in the present invention may be formulated as a solution comprising an emollient. Such compositions preferably contain from about 2% to about 50% by weight of an emollient(s). As used herein, the term emollients refers to materials used for the prevention or relief of dryness, as well as Petition 870260055635, dated 09 / 06 / 2026, p. 17 / 46 11 / 35 for skin protection. A wide variety of suitable emollients are known and can be used in the present invention. Sagarin, Cosmetics, Science and Technology, 2nd Edition, Volume 1, pages 32 to 43 (1972) and the International Cosmetic Ingredient Dictionary and Handbook, editors Wenninger and McEwen, pages 1656-61, 1626, and 1654-55 (The Cosmetic, Toiletry and Fragrance Association, Washington, DC, USA, 7th Edition, 1997) (hereinafter ICI Handbook) contains numerous examples of suitable materials.

[0039] A lotion can be made from a solution. Lotions typically comprise from about 1% to about 20% by weight (e.g., from about 5% to about 10%) of an emollient(s) and from about 50% to about 90% by weight (e.g., from about 60% to about 80%) of water.

[0040] Another type of product that can be formulated from a solution is a cream. A cream typically comprises from about 5% to about 50% by weight (e.g., from about 10% to about 20%) of an emollient(s) and from about 45% to about 85% by weight (e.g., from about 50% to about 75% of water).

[0041] Another type of product that can be formulated from a solution is an ointment. An ointment may comprise a simple base of oils of animal or vegetable origin or semi-solid hydrocarbons. An ointment may comprise from about 2% to about 10% by weight of an emollient(s) plus from about 0.1% to about 2% by weight of a thickening agent(s). A more complete description of thickening agents or viscosity-increasing agents useful to the present invention can be found in Sagarin, Cosmetics, Science and Technology, 2nd Edition, Volume 1, Petition 870260055635, dated 09 / 06 / 2026, p. 18 / 46 12 / 35 pages 72-73 (1972), and in the ICI Handbook, pages 1693-1697.

[0042] The topical compositions useful in the present invention may be formulated as emulsions. If the vehicle is an emulsion, from about 1% to about 10% by weight (for example, from about 2% to about 5%) of the vehicle comprises an emulsifier(s). The emulsifiers may be nonionic, anionic or cationic. Suitable emulsifiers are disclosed, for example, in U.S. Patent No. 3,755,560, U.S. Patent No. 4,421,769, McCutcheon's Detergents and Emulsifiers, U.S. Edition, pages 317-324 (1986), and the ICI Handbook, pages 1673-1686.

[0043] Lotions and creams may be formulated as emulsions. Typically, such lotions comprise from about 0.5% to about 5% by weight of an emulsifier(s). Such creams would typically comprise from about 1% to about 20% by weight (e.g., from about 5% to about 10%) of an emollient(s); from about 20% to about 80% by weight (e.g., from 30% to about 70%) of water; and from about 1% to about 10% by weight (e.g., from about 2% to about 5%) of an emulsifier(s).

[0044] Simple emulsion preparations for skin treatment, such as lotions and creams, of the oil-in-water and water-in-oil type, are well known in the cosmetic art and are useful in the present invention. Multiphase emulsion compositions, such as the water-in-oil-in-water type, as disclosed in US Patent Nos. 4,254,105 and 4,960,764, are also useful in the present invention. In general, such simple or multiphase emulsions contain water, emollients, and emulsifiers as essential ingredients.

[0045] The topical compositions of this invention may also Petition 870260055635, dated 09 / 06 / 2026, page 19 / 46 13 / 35 be formulated as a gel (e.g., an aqueous gel using a suitable gelling agent(s)). Suitable gelling agents for aqueous gels include, but are not limited to, natural gums, acrylic acid and acrylate polymers and copolymers, and cellulose derivatives (e.g., hydroxymethylcellulose and hydroxypropylcellulose). Suitable gelling agents for oils (such as mineral oil) include, but are not limited to, hydrogenated butylene / ethylene / styrene copolymer and hydrogenated ethylene / propylene / styrene copolymer. These gels typically comprise between about 0.1% and 5% by weight of these gelling agents.

[0046] The compositions to be left on the surface of topical application of the present invention may also be formulated as a suspension. In such case, the compositions of the present invention preferably contain a suspending agent. As used herein, the term suspending agent means any material known or otherwise effective in providing suspending, gelling, viscosifying, solidifying and / or thickening properties to the composition or otherwise providing structure to the final product form. Such suspending agents include polymeric or non-polymeric or inorganic gelling agents and thickening or viscosifying agents. Such materials will typically be solids under ambient conditions and include organic solids, silicone solids, crystalline or other gelling agents, inorganic particulates such as clays or silicas, or combinations thereof.

[0047] The concentration and type of suspending agent Petition 870260055635, dated 09 / 06 / 2026, page 20 / 46 14 / 35 selected for use in the compositions to be left on the topical application surface of the present invention will vary depending on the hardness of the desired product, the rheology and / or other related product characteristics. For most suspending agents suitable for use in the present invention, the total concentrations are in the range of about 0.1% to about 40% by weight, more typically from about 0.1% to about 35% by weight of the composition. The concentrations of the suspending agent will tend to be lower for liquid embodiments (e.g., pressurized liquid sprays or other roll-on formulations, etc.) and higher for semi-solid stick embodiments (e.g., creams or soft solids) or solids.

[0048] Non-limiting examples of suitable suspending agents include hydrogenated castor oil (e.g., Castor wax MP80, Castor Wax, etc.), fatty alcohols (e.g., stearyl alcohol), solid paraffins, triglycerides and other similar solid suspending esters or other microcrystalline waxes, silicone and modified silicone waxes. Non-limiting examples of optional suspending agents suitable for use in the present invention are described in U.S. Patent No. 5,976,514 (Guskey et al.), U.S. Patent No. 5,891,424 (Bretzler et al.), the descriptions of which are incorporated herein by reference.

[0049] Other suitable suspending agents include silicone elastomers in concentrations in the range of about 0.1% to about 10% by weight of the composition. Non-limiting examples of such silicone elastomer materials suitable for use as a suspending agent are described in Petition 870260055635, dated 09 / 06 / 2026, page 21 / 46 15 / 35 US Patent No. 5,654,362 (Schulz, Jr. et al.); US Patent No. 6,060,546 (Powell et al.) and US Patent No. 5,919,437 (Lee et al.), the descriptions of which are incorporated herein by reference. These silicone elastomers may also be added for their skin feel or other cosmetic benefits alone, or for such benefits in combination with suspending agent benefits.

[0050] The topical compositions of the present invention can also be formulated in a solid formulation (for example, a water-based stick, soap bar composition, powder or a cleaning cloth containing powder).

[0051] Topical compositions useful in the present invention may contain, in addition to the components mentioned above, a wide variety of additional oil-soluble and / or water-soluble materials conventionally used in compositions intended for use on the skin, hair and nails, in the proportions established in the art. Cosmetically active additional agents

[0052] In one embodiment, the topical composition further comprises another cosmetically active agent in addition to the cellulose particles. A cosmetically active agent is understood to be a compound that has a cosmetic or therapeutic effect on the skin, hair or nails, for example, whitening agents, darkening agents such as self-tanning agents, anti-acne agents, shine control agents, antimicrobial agents, anti-inflammatory agents, antifungal agents, antiparasitic agents, external analgesics, sunscreens, photoprotectors, antioxidants, keratolytic agents, Petition 870260055635, dated 09 / 06 / 2026, page 22 / 46 16 / 35 detergents / surfactants, moisturizers, nutrients, vitamins, energy boosters, antiperspirant agents, astringents, deodorants, hair removers, firming agents, anti-calc agents, and agents for hair, nails, and / or skin conditioning.

[0053] In one embodiment, the agent is selected from, but not limited to, hydroxy acids, benzoyl peroxide, sulfur resorcinol, ascorbic acid, d-panthenol, hydroquinone, octyl methoxycinnamate, titanium dioxide, octyl salicylate, homosalate, avobenzone, polyphenolics, carotenoids, free radical scavengers, spin traps, retinoids such as retinol and retinyl palmitate, ceramides, polyunsaturated fatty acids, essential fatty acids, enzymes, enzyme inhibitors, minerals, hormones such as estrogens, steroids such as hydrocortisone, 2-dimethylaminoethanol, copper salts such as copper chloride, copper-containing peptides such as Cu:Gly-His-Lys, coenzyme Q10, peptides such as those disclosed in U.S. Patent No. 6620419, lipoic acid, amino acids such as proline and Tyrosine, vitamins, lactobionic acid, acetyl-coenzyme A, niacin, riboflavin, thiamine, ribose, electron carriers such as NADH and FADH2, and other botanical extracts such as aloe vera,and its derivatives and mixtures. The cosmetically active agent will typically be present in the composition of the invention in an amount of about 0.001% to about 20% by weight of the composition, for example, about 0.01% to about 10% as well as about 0.1% to about 5%.

[0054] Examples of vitamins include, but are not limited to, vitamin A, B vitamins such as vitamin B3, vitamin B5, and vitamin B12, vitamin C, vitamin K, and vitamin E and Petition 870260055635, dated 09 / 06 / 2026, p. 23 / 46 17 / 35 derivatives of these substances.

[0055] Examples of hydroxy acids include, but are not limited to, glycolic acid, lactic acid, malic acid, salicylic acid, citric acid, tartaric acid, and the like.

[0056] Examples of antioxidants include, but are not limited to, water-soluble antioxidants such as sulfhydryl compounds and their derivatives (e.g., sodium metabisulfite and N-acetylcysteine), lipoic acid and dihydrolipoic acid, resveratrol, lactoferrin, and ascorbic acid and ascorbic acid derivatives (e.g., ascorbyl palmitate and ascorbyl polypeptide). Oil-soluble antioxidants suitable for use in the compositions of this invention include, but are not limited to, butylated hydroxytoluene, retinoids (e.g., retinol and retinyl palmitate), tocopherols (e.g., tocopherol acetate), tocotrienols, and ubiquinone. Natural extracts containing antioxidants suitable for use in the compositions of this invention include, but are not limited to, extracts containing flavonoids and isoflavonoids and their derivatives (e.g., genistein and diadzein), extracts containing resveratrol and the like.Examples of natural extracts include grape seed, green tea, pine bark, and propolis. Other examples of antioxidants can be found on pages 1612-13 of the ICI Handbook. Other materials.

[0057] Several other materials may also be present in the useful compositions of the present invention. These include humectants, proteins and polypeptides, preservatives, and an alkaline agent. Examples of such agents are presented in ICI Handbook, pages 1650-1667.

[0058] The compositions of the present invention may Petition 870260055635, dated 09 / 06 / 2026, page 24 / 46 18 / 35 also include chelating agents (e.g., EDTA) and preservatives (e.g., parabens). Examples of suitable preservatives and chelating agents are mentioned on pages 1626 and 1654-55 of the ICI Handbook. Furthermore, topical compositions useful in the present invention may contain conventional cosmetic adjuvants such as colorants, opacifiers (e.g., titanium dioxide), pigments, and fragrances.

[0059] It has been found that the hydrophobic linear cellulose particles useful in the compositions of the present invention have excellent oil and water absorption properties. It is believed that the compositions of the present invention containing hydrophobic cellulose particles can absorb excess sebum from the skin, thereby reducing skin shine. It is also believed that the compositions of the present invention protect the skin's barrier function by forming a hydrophobic layer on the skin surface and preventing the penetration of surfactants, emulsifiers, or other potentially irritating ingredients. Furthermore, such a hydrophobic layer formed on the skin surface should reduce transepithelial water loss and increase skin hydration. However, in some cases, it may be desirable for the cellulose particles to have enhanced hydrophobic or hydrophilic properties.

[0060] Thus, the hydrophobic linear cellulose particles useful in the compositions of the present invention can be treated with additional hydrophobic or hydrophilic agents, thereby further enhancing the hydrophobic and / or hydrophilic properties respectively, as desired. The hydrophobic agents Petition 870260055635, dated 09 / 06 / 2026, page 25 / 46 19 / 35 may include, but are not limited to, low molecular weight water-soluble organic compounds such as long-chain fatty acids or esters such as stearic acid, oleic acid, castor oil, isododecane, silicone, and their derivatives, non-aqueous water-soluble polymers, for example, high molecular weight methylcellulose and ethylcellulose, and high molecular weight water-insoluble fluoropolymers, etc., siloxanes or polysiloxanes polymerized with the chemical formula [R2SiO]n, where R is an organic group such as methyl, ethyl or phenyl, such as dimethicone, dimethicone copolyol, dimethicone ester; methicone and its derivatives. Hydrophilic agents, such as water-soluble polymers, for example, low molecular weight methylcellulose or hydroxypropylmethylcellulose (PMC); Sugars, for example, monosaccharides like fructose and glucose, disaccharides like lactose, sucrose, or polysaccharides like cellulose, amylose, dextran, etc.Low molecular weight poly(vinyl alcohol) and hydrated silica can also be used to enhance the hydrophilic properties of the cellulose particles used in the compositions of the present invention.

[0061] It has also been found that the textures of the compositions formulated with the hydrophobic linear cellulose particles of the present invention are fluffy, silky and soft, and aesthetically pleasing to the touch during and after application. The term fluffy, as used herein, refers to the apparent density of the hydrophobic linear cellulose particles useful in the compositions of the present invention. The apparent density of the hydrophobic linear cellulose particles useful in the compositions of the present invention is preferably from about 0.1 to about 2 (g / cm3), more preferably about Petition 870260055635, dated 09 / 06 / 2026, page 26 / 46 20 / 35 0.15 to about 1.8 g / cm3 and, most preferably, from about 0.15 to about 1.6 g / cm3. Preferably, the cellulose particles useful in the compositions of the present invention are present in the compositions in an amount of about 1 to about 20% by weight of the compositions, more preferably from about 1 to about 10% by weight of the compositions and most preferably in an amount of about 1 to about 6% by weight of the compositions. Methods of treating or conditioning the skin or hair.

[0062] The methods of the present invention also relate to methods of treating or conditioning the skin or hair with a product to be left on the personal application surface of the present invention. These methods comprise the steps of applying a single-use, disposable, substantially dry personal cleansing product comprising a carrier ingredient and a composition according to the present invention and placing the skin or hair in contact with the product and leaving the product on the skin or hair without removing it. In further embodiments, the methods and compositions of the present invention are also useful for releasing various active ingredients onto the skin or hair.

[0063] The invention will be further described by reference to the following examples to further illustrate the present invention and its advantages. These examples are not intended to be limiting, but illustrative. Compounds are indicated, as the case may be, by their CTFA name or their chemical name, and percentages are given on a weight basis, except where otherwise mentioned. Examples Petition 870260055635, dated 09 / 06 / 2026, page 27 / 46 21 / 35 Example 1: Characterization of hydrophobic and hydrophilic linear cellulose fibers

[0064] Hydrophobic cotton particles and hydrophilic cotton particles mentioned in Table 1 below were characterized as follows: Materials: Table 1 Materials Squalene Water DI Hydrophobic linear cotton particles (available from Goonvean in Cornwall, England) Hydrophobic particles #1 Hydrophobic linear cotton particles (available from IFC in North Tonawanda, NY, USA) Hydrophobic particles #2 Hydrophobic cotton particles (available from Resources of Nature in South Plainfield, NJ, USA) Hydrophilic particles #1 Example 1A: Particle size measurement:

[0065] The particle size of the cellulose materials was determined by the Mie / Fraunhofer laser scattering method using a Malvern Hydro 2000S particle size analyzer following this procedure: 1. Ensure that the cell windows and lenses are clean and free of scratches. 2. Wash (using deionized water) and drain the accessory at least twice to eliminate any contamination from previous samples. 3. Turn off the pump / agitator and turn on the ultrasonic device for 30 seconds to allow air bubbles to dissipate. 4. Fill the dispersion unit with DI water. Adjust the pump / agitator speed to 2100 rpm, and then... Petition 870260055635, dated 09 / 06 / 2026, page 28 / 46 22 / 35 Turn off the pump for about 3 seconds to allow the air to dissipate. Then slowly turn the pump back on at 2100 rpm. Top up the dispersion unit with water to replace the displaced air volume. 5. Add 4 drops of 5% IGEPAL CA 630 (non-ionic detergent) to the tank and allow dispersion before measuring the background. If this concentration causes bubble formation, clean the unit and repeat the procedure using 2 drops of surfactant. To ensure the background provides a clean reading, follow the 2-150 and 20-20 rule (The first two detectors should have a light intensity less than 150 units and detector number 20 should have a light intensity less than 20 units). 6. Once the system has been cleaned, add the diluted sample to be measured to the dispersion unit in an amount of approximately 2 mg in 10 grams of water. 7. When the obscuration caused in the particles in the sample is 2 to 5%, start the measurement. Record D50 and D90 in microns. (D50 refers to 50% of the particles being smaller than the value; D90 refers to 50% of the particles being smaller than the value) 8. The experiment was repeated three times, and the average of the three results was recorded as the final value.

[0066] The average particle size of various cellulose particles outlined in Table 1 was determined and is shown in Table 2. Petition 870260055635, dated 09 / 06 / 2026, page 29 / 46 23 / 35 Table 2 Particle size D90 (microns) Particle size D80 (microns) Particle size D50 (microns) Hydrophilic cotton particles 170 125 70 Hydrophobic linear cotton particles #1 500 200 55 Hydrophobic linear cotton particles #2 270 125 50 Example 1B: Contact angle

[0067] The contact angles of various cellulose particles outlined in Table 1 were determined as follows:

[0068] 40 grams of the cotton particles shown in Table 1 were placed in a particle sample holder; the surface was compressed with a consistent force to create a smooth, compact particle surface. A 500 pl micro syringe filled with test liquid (water), 0.52 mm needle, was used to dispense and deposit 5 pl droplets onto the surface. The droplet contact angles on each of the cotton particle samples were measured and calculated using a Video-based DataPhysics OCA 20 optical contact angle measurement system with SCA20 software from three replicate tests on each sample; the results are shown in Table 3. Table 3 Material | Initial water contact angle (degrees) | Hydrophobic linear cotton particles #2 | 136.2 (5.8)* | Hydrophilic cotton particles | 39.1 (4)* | Hydrophobic linear cotton particles #1 | 122.3 (3.2)* Petition 870260055635, dated 09 / 06 / 2026, page 30 / 46 24 / 35 *represents standard deviation

[0069] As shown in Table 3, hydrophobic cotton particles exhibited a larger angle of contact with water compared to hydrophobic cotton particles. Example 1C: Infrared Spectra:

[0070] Infrared spectrum analysis was performed on three cotton particles as follows:

[0071] Solvent extraction from cotton materials using methylene chloride was conducted and followed by IR analysis of the evaporated residues shown in Figures 1 and 2 of the present invention.

[0072] The spectra (shown in Figures 1 and 2) showed extract residues from the two hydrophobic linear cotton particles (#2 and #1) along with a dimethicone reference spectrum.

[0073] Solvent extractions of the two hydrophobic cotton materials (IFC and Goonvean) showed a significant amount of waxy semi-solid residue, and relatively little from the hydrophilic cotton materials. This waxy semi-solid residue coating is believed to be responsible for the hydrophobic nature of these two hydrophobic cotton particles.

[0074] Infrared analysis of hydrophobic cotton residues #2 and #1 shows that both contain silicone (dimethicone or related polymer) along with other components. Residue #2 includes a long-chain hydrocarbon wax-like material (as indicated by split peaks around 1375 and 725 cm-1) while residue #1 includes an ester component (as indicated by IR peaks around 1735 and 1250 cm-1). Petition 870260055635, dated 09 / 06 / 2026, page 31 / 46 25 / 35

[0075] The hydrophilic cotton particles (Virgin Cotton Flock) showed negligible extractable residue. The morphology of this material was significantly different from the other two materials, indicating a higher degree of processing, reducing much of the cotton fiber into a fine powder material. The hydrophilic nature of this material is probably due to the inherent absorbent properties of cotton and the absence of a repellent finishing treatment.

[0076] Additionally, infrared analysis showed that all three cotton materials are typical cellulosic materials. Characterization of the three different cotton materials showed that the hydrophobic (#2 and #1) is composed of a silicone-based hydrophobic treatment. In contrast, the hydrophilic cotton does not have a silicone-based repellent treatment. Example 2: Specific surface area

[0077] Inverse gas chromatography (IGC) has been reported in several articles as a good method for determining isotherms at finite concentration and ambient temperatures, using organic probe molecules. (Thielmann, F., Burnett, DJ and Heng, JYY (2007) Determination of the surface energy distributions of different processed lactose. Drug Dev. Ind. Pharm, 33, 1240-1253. And see also YlaMaihaniemi, PP et al. (2008) Inverse gas chromatographic method for measuring the dispersive surface energy distribution for particulates. Langmuir, 24, pages 955-9557.)

[0078] The specific surface area was determined with IGC using octane by measuring the isotherms of Petition 870260055635, dated 09 / 06 / 2026, pages 32 / 46 26 / 35 octane adsorption at 30 °C and 0% relative humidity. The results of these determinations are shown in Table 4. BET is a specific surface area measurement known to those skilled in the art. Table 4 Particle Specific Surface Areas (BET / IGC) Sample Surface area (m2 / gr.) Hydrophilic cotton particles 1.4 Hydrophobic linear cotton particles (#1) 1.23 Hydrophobic linear cotton particles (#2) 1.6 Example 3: Absorption and retention capacity:

[0079] The olive oil absorption capacity of the dry cotton particles in Table 1 was measured under standard conditions (i.e., ambient temperature and pressure). The saturated particles were also subjected to centrifugal force to measure their retention power.

[0080] When a porous medium containing liquid is subjected to a force, the liquid is gradually evacuated from large pores, then from increasingly smaller pores as the pressure increases. A medium containing a high pore volume distribution of smaller pores (or effective pores) can retain more liquid under higher constraint, and this retention power can be a useful characteristic when the desired function of the medium is to retain a liquid (sponge effect).

[0081] To evaluate the particle retention power, combinations of particles / oversaturated oil were subjected to centrifugal force (8000 rpm, 300 seconds) and the remaining oil was measured. The results of this measurement are Petition 870260055635, dated 09 / 06 / 2026, pp. 33 / 46 27 / 35 shown in Table 5.

[0082] After acceleration, the remaining oil can be expressed as a ratio of the amount of saturating oil (= mass of remaining oil / mass of oil initially in the blend) or the amount of remaining oil can be expressed as a mass fraction of the oil / particle mixture (= mass of remaining oil / mass of the oil / particle complex). The two calculations can provide different insights and are expressed in the following table. Table 5 Absorption and retention capacity of glyceryl trioleate (olive oil) on cotton particles Sample Olive oil absorption capacity (% by weight) Retention @ 8000 rpm (% saturation) Retention @ 8000 rpm (% blend) Hydrophilic cotton particles 130 14 16 Hydrophobic linear cotton particles (#1) 445 14 38 Hydrophobic linear cotton particles (#2) 322 7 18

[0083] The two hydrophobic linear cotton particles (#1 and #2) demonstrated very high oil absorption in the dry state, when loosely packed. Additionally, the hydrophobic linear cotton particles (#1) retained a high amount of triglyceride even under applied acceleration. Example 4: Oil absorption rate:

[0084] The rate at which a material absorbs oil can be determined by the following procedure:

[0085] A template of a 6x4 cm rectangle was cut from 0.25 mm thick paper. With a rectangular window Petition 870260055635, dated 09 / 06 / 2026, pages 34 / 46 A 28 / 35 4x2 cm slide was cut in half with 1 cm of paper around the edge of the window. A glass microscope slide was weighed and its mass recorded. The template was placed on the slide and the test material dispensed into the template window. The material was spread across the window with a metal spatula to create a uniform rectangular layer with a mass of ~0.24 g (±0.01 g). The template was carefully removed, the edges of the slide cleaned with a spatula or gloved fingertip as needed, and the mass of the slide + material recorded. The slide (with the oil-absorbing particle layer) was placed flat in an incubator at 32°C. 0.0858 g of the tallow component of interest was dispensed via a 0-100 pL (liquid) pipette onto the slide on one side and in contact with the particle layer. (For squalene, 100 pL was used; for triolein, 94.3 pL was used based on densities declared by the suppliers).The slide was left to rest in the incubator for 15 seconds (for follow-up testing), with a timer started as soon as the drop was dispensed. After 15 seconds, the slide was removed from the incubator and any unabsorbed sebum component was carefully wiped from the slide using a Kimwipe. The slide was weighed to determine the amount of sebum component absorbed by the particles during the absorbance period. The above steps were repeated for each slide, with each particle / sebum component combination tested at least in triplicate. Ratios were calculated to show the mass of sebum component absorbed per mass of oil-absorbing particles in 15 seconds. The results of this determination are presented in Figure 3 of the present invention. Petition 870260055635, dated 09 / 06 / 2026, pages 35 / 46 29 / 35

[0086] Figure 3 demonstrates that hydrophobic cotton particles (hydrophobic cotton particles #1) absorb both squalene and triglyceride much faster than hydrophilic cotton particles. Example 5: Rate of water absorption:

[0087] The water absorption rate of materials was determined by the procedure presented as follows:

[0088] A gravimetric absorption test (GAT) method was used to determine the water absorption kinetics of hydrophobic cotton particles vs. hydrophilic cotton particles. The cotton particle sample was loaded into a small cylinder container, and water was introduced into contact with the cotton particles through a water reservoir on a scale, and the change in water weight resulting from water transfer or absorption by the cotton particles was electronically recorded by a computer during the duration of the study. The absorption rate was calculated and plotted for different cotton particle samples.

[0089] As shown in Figure 4, hydrophobic cotton particles had a slower rate of water absorption than non-hydrophobic cotton particles. Example 6: Water absorption capacity and oil absorption capacity [00 90] The water absorption capacity and oil absorption capacity of materials can be determined by the procedures presented below in Examples 6A and 6B.

[0091] Each experiment was repeated in triplicate for hydrophobic cotton particles #1, hydrophilic cotton particles (#1), and hydrophobic cotton particles #2. Petition 870260055635, dated 09 / 06 / 2026, pages 36 / 46 30 / 35 Example 6A: Measurement of hydrophobicity and oil absorption.

[0092] The balance was tared with the particle samples. Squalene was then added dropwise using a disposable pipette until the sample appeared nearly saturated. A metal spatula was used to thoroughly mix the oil with the particles until saturation (after mixing, the spatula was wiped against the side of the weighing container to ensure no material loss). The term saturation as used herein is defined as the mixture that is able to retain all available squalene such that the bottom of the container appeared dry. This determination was based on the appearance of the mixture and the condition of the weighing container. The total number of grams of squalene was recorded and the relative oil absorption ratio was calculated by dividing the total weight of oil by the total weight of cotton materials. The results of performing this procedure are presented in Figure 5 of the present invention. Example 6B: Measuring water absorption.

[0093] Following a method similar to that described in example 6A, but replacing water with the oil material, water absorption was measured. The results of this test are shown in Figure 6. Example 7: Oil retention

[0094] Oil retention was determined using the following procedure:

[0095] A test site was marked with a 2 cm diameter circle on an oil-impermeable white card. Approximately 6.2 mg of artificial sebum was applied evenly within the marked circle to create an oily patch, with a Sebumeter reading recorded as a pre-sebum reading. Petition 870260055635, dated 09 / 06 / 2026, pages 37 / 46 31 / 35 Treatment P. Approximately 25 mg of the test sample was weighed and applied evenly over the test site. Sebum in each test was measured with a sebumeter at the site, and sebumeter readings were recorded 10 minutes after product application. The procedure was repeated for 2 replicates for each test product, and the mean S was calculated to provide the sebum level with product application.

[0096] In-vitro sebum absorption was calculated using the following equation: % change in sebum level = (SP) / P where S = average pre-treatment sebumeter reading P = average post-treatment sebum reading

[0097] In-vitro oil absorption studies were conducted at initial storage and three months at room temperature (RT) (22 °C) for the leave-in conditioners mentioned in the table below. The in-vitro sebum absorption test showed that the addition of hydrophobic cotton particles (#1) at the 2% level in a Formulation B leave-in conditioner increased sebum absorption in-vitro 2x times vs. the placebo Formulation A leave-in conditioner. Formula B with 2% hydrophobic cotton particles (#1) leave-in conditioner has a slightly higher, but not significantly different, sebum absorption in-vitro than Formulation C with 2% hydrophilic cotton particles. Petition 870260055635, dated 09 / 06 / 2026, pages 38 / 46 32 / 35 Table 6 Ingredient (%) Formula A Formula B Formula C 90 00 00 Deionized water 87.81 85.81 85.81 Hydroxyethylcellulose 0.50 0.50 0.50 Part #1 Quaternium-91 and cetrimonium methosulfate and cetearyl alcohol 1.00 1.00 1.00 Benyl alcohol 1.50 1.50 1.50 Stearyl alcohol 1.25 1.25 1.25 Cetyl alcohol 3.00 3.00 3.00 Part #2 Dimethicone 1.00 1.00 1.00 Amodimethicone 0.25 0.25 0.25 Dimethicone 2.00 2.00 2.00 Part #3 Polyquaternium-37 and Propylene Glycol Dicaprate / Dicaprate and PPG-1 Trideceth-6 0.20 0.20 0.20 Phenoxyethanol & Caprylic Glycol 1.00 1.00 1.00 Water (and) Hydrolyzed Lupine Seed Extract 0.01 0.01 0.01 Fragrance 0.35 0.35 0.35 Hydrophobic Cotton Particles (#1) 2.00 Hydrophilic Cotton Particles 2.00 Sodium Hydroxide 0.13 0.13 0.13 Total 100.00 100.00 100.00

[0098] The compositions presented in Table 6 were prepared according to the following method: 1. Deionized water and hydroxyethylcellulose were added to a mixing container and heated to 75-80°C. 2. In a separate container, the ingredients listed in Table 6 above as Part #1 were added and heated to 75°-80°C until all were melted. Petition 870260055635, dated 09 / 06 / 2026, pages 39 / 46 33 / 35 ingredients. 3. After melting all the ingredients of Part #1, the hydroxyethylcellulose solution was phased with Part #1 and mixed until homogeneous. Cooling to below 40°C was then initiated. 3. At 60°-65°C, the ingredients from Part #2 were added one at a time, allowing for good mixing, until the batch was homogeneous. 4. At or below 40°C, the ingredients from Part #3 were added. 5. In a separate container, sodium hydroxide and DI water were premixed and the batch pH adjusted to pH 4.0-4.5. 6. The ingredients were adjusted to 100% by weight in the batch, and the batch was homogenized for 1-5 minutes. 7. The cotton particles were added and the batch mixed until homogeneous.

[0099] The graph presented in Figure 7 of the present invention reflects the degree of sebum absorption resulting from the above-mentioned procedure for each composition (Formulations A to C). As shown in the figure, hydrophobic cotton powder retained a significantly greater amount of oil (i.e., sebum) for leave-in hair conditioning compositions than compositions containing hydrophilic cotton particles. Example 8: Sunscreen composition

[0100] Sunscreen compositions to be left on the application surface according to the present invention can be made according to the previous examples using the following ingredients: Petition 870260055635, dated 09 / 06 / 2026, pp. 40 / 46 34 / 35 #1 #2 #3 List of ingredients Usage range Usage range Usage range % weight / weight % weight / weight % weight / weight Purified water qsqs qs . Lauryl PEG / PPG-18 / 18 dimethicone 0.00-2.00 Carbomer 0.00-1.00 Acrlates / C10-30 alkyl acrylate crosspolymer 0.00-1.00 Dimethicone 0.000-15.00 Glycerin 0.00-10.00 0.00-10.00 0.00-10.00 Disodium EDTA 0.00-1.00 0.00-1.00 0.00-1.00 Potassium cetyl phosphate 0.00-5.00 0.00-5.00 Triethanolamine 0.00-1.00 0.00-1.00 BHT 0.00-1.00 0.00-1.00 0.00-1.00 Steareth-21 0.00-2.00 0.00-2.00 Steareth-2 0.00-1.00 0.00-1.00 Isododecane 0.00-30.00 Cetyl alcohol 0.00-5.00 0.00-5.00 Ethylhexyl methoxycinnamate 0.00-10.00 Phenylbenzimidazole sulfonic acid 0.00-5.00 Zinc oxide 0.00-10.00 0.00-10.00 0.00-10.00 Titanium dioxide 0.00-12.00 0.00-12.00 0.00-12.00 C12-15 alkyl benzoate 0.00-10.00 0.00-10.00 0.00-10.00 Preservatives 0.00-2.00 0.00-2.00 0.00-2.00 Hydrophobic cotton particles 0.00-5.00 0.00-5.00 0.00-5.00 Fragrance qsqsqsSodium hydroxide q.s. q.s. q.s. Total 100 100 100. Example 9: Liquid makeup with cotton particles

[0101] Makeup compositions to be left on the application surface according to the present invention can be made according to the previous examples using the following ingredients: Petition 870260055635, dated 09 / 06 / 2026, pp. 41 / 46 35 / 35 INCI Name % weight / weight % weight / weight % weight / weight Sodium chloride 1.00 1.00 1.00 Butylene glycol 2.00 2.00 2.00 Disodium EDTA 0.20 0.20 0.20 Dimethicone 9.90 9.90 9.90 C30-45 alkyl methicone olefin 1.20 1.20 1.20 Isododecane 12.20 12.20 12.20 Phenoxyethanol 1.00 1.00 1.00 Cetyl PEG / PPG-10 / 1 dimethicone 4.00 4.00 4.00 VP / hexadecene copolymer 1.00 1.00 1.00 Dimethicone / PEG 10 / 15 crosspolymer dimethicone 6.00 6.00 6.00 Dimethicone 3.60 3.60 3.60 Titanium dioxide (and) Triethoxycaprilylsilane 8.00 8.00 8.00 Iron oxide (and) Triethoxycaprilylsilane 1.68 1.68 1.68 Iron oxide (and) Triethoxycaprilylsilane 0.44 0.44 0.44 Iron oxide (and) Triethoxycaprilylsilane 0.26 0.26 0.26 Salicylic acid 0.50-2.00 Sulfur 3.00-10.00 Hydrophobic cotton particles 0-20 0-20 0-20 Water DI qsq s q. s 10% citric acid solution, adjust to pH = 4-5 Total 100 100 100 Petition 870260055635, dated 09 / 06 / 2026, pages 42 / 46

Claims

1 / 3 CLAIMS 1. A skin treatment composition, to be left on the application surface, characterized by comprising: - hydrophobic linear regenerated cotton particles, with an oil absorption and retention capacity of 150 to 500% by weight of oil / weight of particles and the water contact angle of said hydrophobic linear regenerated cotton particles being greater than 90 degrees, treated with a hydrophobic coating agent, said hydrophobic coating agent being selected from the group consisting of long-chain fatty acids or esters, such as silicone and its derivatives and water-insoluble polymers, such as polymerized siloxanes or polysiloxanes, said regenerated cotton particles being generated from nonwoven materials or cloth previously formed from cotton plants or cotton fibers, said regenerated cotton particles having an average length of 1 to 500 µm,a particle aspect ratio of 2 to 25 and a thickness of 1 to 500 µm; and a cosmetically acceptable vehicle.

2. Skin treatment composition, to be left on the application surface, according to claim 1, characterized in that said oil absorption and retention capacity of said hydrophobic linear regenerated cotton particles is 300 to 500% oil weight / particle weight.

3. Skin treatment composition, to be left on the application surface, according to claim 1, characterized in that said angle of contact with water is greater than 100 degrees.

4. Skin treatment composition, to be left on the application surface, according to claim 1, characterized in that said water contact angle is greater than 120 degrees.

5. Skin treatment composition, to be left on the application surface, according to claim 1, characterized in that said regenerated cotton particles are coated with a hydrophobic agent selected from the group consisting of metal soap, organic wax, synthetic wax, long-chain fatty acids, long-chain fatty esters, non-aqueous soluble polymers, high molecular weight water-insoluble fluoropolymers and polymerized siloxanes.

6. Skin treatment composition, to be left on the application surface, according to claim 1, characterized in that said composition further comprises an aqueous solvent.

7. A composition for skin treatment, to be left on the application surface, according to claim 1, characterized in that said composition also comprises at least one emollient.

8. Skin treatment composition, to be left on the application surface, according to claim 1, characterized in that the size of said hydrophobic linear regenerated cotton particles is from 2 to 300 µm.

9. Skin treatment composition, to be left on the application surface, according to claim 1, characterized by comprising, Petition 870260055635, dated 09 / 06 / 2026, page 44 / 46 3 / 3, at least one emollient.

10. A composition for skin treatment, to be left on the application surface, according to claim 1, wherein said composition is characterized by comprising 1 to 20 percent by weight of said regenerated cotton particles.

11. A composition for skin treatment, to be left on the application surface, according to claim 1, wherein said composition is characterized by comprising 1 to 10 percent by weight of said regenerated cotton particles.

12. Skin treatment composition, to be left on the application surface, according to claim 1, wherein said composition is characterized by comprising 1 to 6 percent by weight of said regenerated cotton particles. Petition 870260055635, dated 09 / 06 / 2026, pp. 45 / 46

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