STENT
The stent design with V-shaped support sections and a zinc-silver alloy addresses the challenge of insufficient force in soft-material stents, providing enhanced radial support, flexibility, and biocompatibility, with improved X-ray visibility.
Patent Information
- Application Number
- BR112021023005
- Authority / Receiving Office
- BR · BR
- Patent Type
- Patents
- Current Assignee / Owner
- Priority Date
- 2019-05-16
- Filing Date
- 2020-05-06
- Publication Date
- 2026-07-28
- Estimated Expiration
- 2040-05-06
AI Technical Summary
Existing stents made of relatively soft materials struggle to provide sufficient radial vertical positioning force, especially when made from bioabsorbable materials like polylactic acid (PLA) or poly-L-lactic acid (PLLA), which have low mechanical stability and can lead to biocompatibility issues and adverse reactions.
The stent design incorporates V-shaped support sections with rib angles ranging from 90° to 150°, preferably 105° to 115°, and uses a bioabsorbable zinc alloy with 90.0 to 99.95% zinc and 0.05 to 10.0% silver or titanium, enhancing radial vertical positioning force while ensuring biocompatibility and X-ray visibility.
The design achieves a high radial vertical positioning force, flexibility, and biocompatibility, reducing the risk of thrombosis and allowing for easier X-ray observation, while avoiding the need for surgical removal.
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Abstract
Description
1 / 19 STENT
[0001] The present invention relates to a stent for transluminal implantation in hollow organs, particularly in blood vessels, ureters, esophagus, colon, duodenum or biliary tract, with an essentially tubular body, which extends along an axial direction and can be converted from a compressed state with a first cross-sectional diameter to an expanded state with a second enlarged cross-sectional diameter. The stent comprises a large number of cells that are defined by rib-like edge elements formed by the tubular body. The edge elements comprise at least one support strut that runs annularly around the axial direction.
[0002] Stents of this type are used for the recanalization of pathologically altered hollow organs. In this case, the stents are applied in a compressed state with the first cross-sectional diameter by an insertion catheter at the position to be treated, inside the hollow organ, where they are expanded through different measurements over a diameter that corresponds to the diameter of the healthy hollow organ, in such a way that a support effect is obtained for the hollow organ, for example, a vascular wall. After expansion, the stent presents, in particular, the second cross-sectional diameter.
[0003] To provide the support effect, it is necessary that the stent be able to generate the greatest possible vertical positioning force, that is, a force in the radial direction, which presses, for example, against the wall of a blood vessel.
[0004] Therefore, the underlying objective of the invention is Petition 870210105768, dated 11 / 16 / 2021, page 10 / 37 2 / 19 to improve a stent of the type mentioned above in such a way as to provide the greatest possible vertical positioning force, particularly, also when the stent is made of relatively soft materials.
[0005] This objective is solved by a stent with the characteristics of claim 1.
[0006] The stent according to the invention is characterized in that the support strut has at least one V-shaped support section, comprising a rib angle of 90° to 150°, when the stent has the second cross-sectional diameter. The V-shaped support section may be formed by two legs. The legs may be part of the edge elements.
[0007] The invention is based on the knowledge that a relatively wide rib angle of 90° to 150° can create a high radial vertical positioning force, even if the stent is made, for example, of materials with much lower tensile strength. Unlike common coronary stents, for example, which have rib angles in the range of 60° to 80°, according to the invention, a series of advantages can be achieved as explained in more detail below.
[0008] In this particular case, the rib angle should be understood as the angle that is fixed or defined by the two legs of the V-shaped support section. In this case, the rib angle is determined, unless otherwise indicated in this document, whenever the stent is in its expanded state with the second cross-sectional diameter, the second cross-sectional diameter normally defining the nominal diameter. The Petition 870210105768, dated 11 / 16 / 2021, page 11 / 37 3 / 19 nominal diameter is the diameter that is permanently required for regular use of the stent.
[0009] In general, stents can be formed from the aforementioned edge elements, which can also be referred to as stent struts, and which together form a reticular structure that in turn defines the tubular body of the stent.
[0010] The border elements in this case preferably form a plurality of cells, wherein a given cell comprises the respective border element that limits it and can be joined to other cells by means of other border elements.
[0011] Preferred embodiments of the invention are to be derived from the description, dependent claims and drawings.
[0012] According to a first advantageous embodiment, the rib angle has an angle of 90° to 140°, preferably from 100° to 130°. More preferably, the rib angle can have an angle of 105° to 115°. The angle specifications mentioned herein should be understood so that the limits mentioned are respectively included. In particular, the rib angle can be 110°. It has been proven that, in the range around 110°, a particularly high radial vertical positioning force can be achieved.
[0013] For clarity, it should be noted that the rib angle mentioned above refers again to the state in which the stent is enlarged at the second cross-sectional diameter. At the cross-sectional diameter Petition 870210105768, dated 11 / 16 / 2021, page 12 / 37 4 / 19 transverse, in which the stent can be introduced in a reduced form within the body, the angle of the V-shaped support section can be significantly smaller and particularly even 0° when the legs run parallel. More precisely, the angle of the V-shaped support section, in the compressed state with the first cross-sectional diameter, can be particularly less than 30°, preferably less than 15°.
[0014] According to another advantageous embodiment, the edge elements comprise, at least in sections, a bioabsorbable material, preferably consisting of or containing zinc (Zn). By applying a bioabsorbable material, the stent does not remain in the body indefinitely nor does it need to be surgically removed. Instead, after a few months, the material dissolves in the body and is naturally absorbed by material exchange processes and is completely eliminated. In this way, biocompatibility problems and the body's own defense reactions can be reduced, which can lead to the reconnection of vessels (for example, due to late arteriosclerosis or thrombus formation).
[0015] Particular polymeric materials are known as bioabsorbable materials, for example, polylactic acid (PLA) or poly-L-lactic acid (PLLA). However, such polymeric materials exhibit low mechanical stability, so a bioabsorbable material with zinc content is preferably used. The use of zinc or a zinc alloy can also significantly increase the X-ray visibility of the stent in Petition 870210105768, dated 11 / 16 / 2021, p. 13 / 37 5 / 19 in relation to PLA, PLLA or magnesium alloys. As a result, stent insertion under radiographic observation becomes much simpler and separate X-ray markers are not necessarily required.
[0016] Other known bioabsorbable materials are magnesium and magnesium-containing alloys, as already indicated above. In the body, magnesium reacts adversely with the water contained in body tissue, releasing energy to form magnesium hydroxide and hydrogen. The hydrogen is then present in gaseous form and can lead to life-threatening embolisms in the bloodstream, for example. Magnesium alloy stents are therefore typically designed with PLLA in order to control the decomposition process. Furthermore, the mechanical properties, especially with regard to elongation at break, are inferior to those of zinc alloys.
[0017] In particular, pure zinc or a zinc alloy can be used as a bioabsorbable material. The zinc alloy can be produced, for example, by adding silver (Ag) and / or titanium (Ti). The zinc alloy may preferably contain 90.0 to 99.95% by mass of zinc and 0.05 to 10.0% by mass of silver. 0.05 to 10.0% by mass of titanium may also be added to the zinc alloy. Preferably, however, a proportion of 0.9 to 4.0% by mass of silver and / or titanium is used, the zinc alloy also consisting of zinc. In addition to zinc, only 3.0% by mass of silver and / or titanium is particularly preferred, particularly between 2.8 and 3.2% by mass. A combination of 3.0% by mass of silver and 97% by mass of zinc proved to be advantageous in terms of mechanical stability for the Petition 870210105768, dated 11 / 16 / 2021, p. 14 / 37 6 / 19 stents described in this document.
[0018] According to another advantageous embodiment, the bioabsorbable material consists of zinc and silver, wherein the bioabsorbable material contains 90.0 to 99.95% by mass of zinc and 0.05 to 10.0% by mass of silver. The bioabsorbable material may therefore consist exclusively of zinc and silver. Such an alloy is described in European patent application number EP 16 702 899.2.
[0019] The zinc alloys mentioned in this document of zinc and silver and / or titanium may, for example, have a tensile strength of 180 to 210 MPa, preferably 190 to 200 MPa. The tensile strength is lower, for example, than 316L stainless steel, which is not bioabsorbable and has a tensile strength of about 586 MPa. Through the rib angle selected according to the invention, however, a stent with higher radial vertical positioning strength can be obtained.
[0020] The zinc alloys referred to here may also exhibit an elongation at break in the range of 80 to 180%, for example, 80 to 100%, preferably in the range of 90 to 100%. The specific elongation at break is around how many percent a material can be stretched until it breaks.
[0021] This high elongation at break value for the zinc alloys mentioned allows for significantly more flexible stent support struts than would be possible, for example, with 316L stainless steel (elongation at break 35%) or with pure zinc (elongation at break). Petition 870210105768, dated 11 / 16 / 2021, page 15 / 37 7 / 19 %). By means of this, it is permitted, in particular, to achieve the enlarged rib angle according to the invention and also to create the enlarged angle difference of the V-shaped support section between the state with the first compressed cross-sectional diameter and the second expanded cross-sectional diameter.
[0022] It should be noted that the values specified here for elongation at break apply to the actual processed bioabsorbable material of the stent. Before actual processing, the bioabsorbable material may be processed, for example, by extrusion and / or tubular stretching, whereby the elongation at break (and also other material properties) may change significantly compared to the pure alloy.
[0023] According to another advantageous embodiment, the support brace comprises several V-shaped support sections, which respectively have a rib angle in the aforementioned range, such that at least in sections a zigzag shape of the support brace results. Further V-shaped support sections may also be arranged one behind the other, such that a zigzag shape of the support brace results. The “openings of the V-shaped support section, defined by the legs, indicate, in this case, respectively, alternating, in opposite directions.
[0024] The rib angles of the individual support sections may be respectively distinct, however, they fall within a range mentioned previously. Alternatively, the rib angle may be equal at least in part or entirely, in which case a deviation of up to 10% is allowed. Petition 870210105768, dated 11 / 16 / 2021, p. 16 / 37 8 / 19 preferably, up to 5%, particularly preferably up to 3%, is considered equal. Through rib angles, or at least similar ones, a homogeneous stent structure can be achieved. In particular, the support strut can be formed, for example, by 8, 12 or 16 V-shaped support sections.
[0025] According to another advantageous embodiment, in the rib angle range, a longitudinal connector is applied to the support brace, which joins the support brace with at least one other support brace. The longitudinal connector can be applied, in particular, at the point where both legs of the V-shaped support sections meet one another. The rib angle is preferably determined without considering the longitudinal connector.
[0026] Preferably, the longitudinal connector extends at least essentially parallel to the axial direction and, therefore, preferably, for example, at a right angle to the support strut. The longitudinal connector is particularly an edge element, with two longitudinal connectors and the associated support strut sections defining or stretching a cell.
[0027] The longitudinal connector may preferably have, in a superior view, for example, a circular or elliptical position marker. The position marker may comprise a thickening of the bioabsorbable material or consist of such thickening. The position marker may allow, in particular, the positioning of the stent on a catheter. The position marker is preferably placed at the edge or next to the support strut. Petition 870210105768, dated 11 / 16 / 2021, p. 17 / 37 9 / 19
[0028] Along the course of the support strut around the axial direction, the rib angle may be found, respectively, alternately, on a side away from the longitudinal connector and on a side of the support strut facing the longitudinal connector. If the rib angle is found on the side facing the longitudinal connector, then the longitudinal connector may be located, for example, in the center of the rib angle.
[0029] Furthermore, a longitudinal connector can only be applied in the range of every second rib angle. Viewed along the circumferential direction of a support brace, longitudinal connectors can be applied alternately on opposite sides of the support brace. Expressed another way, there can be V-shaped support sections per support brace, as longitudinal connectors. Alternatively, there can be many identical V-shaped support sections as longitudinal connectors.
[0030] Preferably, on each support strut, several longitudinal connectors, particularly, precisely two or three longitudinal connectors, can be applied on the same side. This means that two adjacent support struts are joined together precisely by two or three longitudinal connectors. By joining with two or three longitudinal connectors, it is possible to form the stent flexibly, so that it can adapt to the curvatures and curves of the hollow organ to be supported. At the same time, the support braces provide a greater radial vertical positioning force.
[0031] The stent may present, in particular, a Petition 870210105768, dated 11 / 16 / 2021, p. 18 / 37 10 / 19 central part, which consists exclusively of the support struts and the longitudinal connectors attached to the support struts. The central part, viewed axially, is located between both ends of the stents.
[0032] According to another advantageous embodiment, the support brace runs at least essentially radially around the axial direction, such that the axial direction forms a normal vector in the plane defined by the support brace. For the determination of the plane defined by the support brace, a zigzag shape of the support brace is not considered, but possibly an average. In other words, the support brace is not arranged obliquely or inclined laterally with respect to the axial direction. Instead, the axial direction remains vertical in the plane defined by the support brace. Consequently, the support braces do not particularly intersect. Preferably, all support braces are arranged in this way.
[0033] According to another advantageous embodiment, the stent can be enlarged by a third cross-sectional diameter, which is larger than the second cross-sectional diameter, wherein the rib angle is enlarged by at least 120°, preferably by at least 140° or 160°, when the stent has the third cross-sectional diameter. In particular, the third cross-sectional diameter may also have a rib angle of at least 165° or 170°. The rib angle, in the third cross-sectional diameter, may also be larger, by around at least 10° or 20°, than the second cross-sectional diameter.
[0034] For example, in the coronary area, it can be Petition 870210105768, dated 11 / 16 / 2021, page 19 / 37 11 / 19 when inserting the stent, it is necessary to briefly enlarge the stent to the third cross-sectional diameter, so that the stent is then better fitted into the respective vessel and maintains a sufficiently sized lumen to ensure free blood flow. This suppresses the adhesion of blood platelets which could otherwise lead to thrombosis.
[0035] The third cross-sectional diameter may be larger, at least 7 to 20% (e.g., 10% or 14%) than the second cross-sectional diameter. Particularly depending on the zinc alloy mentioned in this document, the stent material may be flexible such that the mentioned rib angle can also be achieved at the third cross-sectional diameter without material rupture. The maximum rib angle at the third cross-sectional diameter may be at most at 170°, preferably at most 150°.
[0036] According to another advantageous embodiment, the stent is constructed in the same way, except for the axial end regions. This means that the stent has the same structure everywhere and can only deviate from this similar structure at its ends, for example. By axial ends is meant the ends where, for example, blood enters or exits, provided that the stent is implanted in an unbranched bloodstream.
[0037] Alternatively, it is also possible that, within a predefined area of the vessel branching surface, the edge elements have a smaller mass than the edge elements in another area of the same size, the smaller mass being achieved, for example, by Petition 870210105768, dated 11 / 16 / 2021, p. 20 / 37 12 / 19 thinner edge elements. The predefined area of the vessel branching surface is particularly a curved surface that results when the stent is in an expanded state with the second cross-sectional diameter.
[0038] The vessel branching surface area serves to be positioned in a vessel branch, and then, due to the smaller mass in the vessel branching surface area strip, it is possible to dilate the branch more easily. Through this, a recess can be developed in the vessel branching surface area strip, which allows, for example, free blood flow through the vessel branch.
[0039] To achieve a smaller mass, the pass, by length of path of the edge elements, can be, for example, around at least 15%, preferably around at least 25% smaller than that of the remaining edge elements. Correspondingly, the edge elements and, with that, for example, also a strip of a support brace, which runs along the surface area of the vessel branch, can be around, for example, 25% thinner or narrower.
[0040] According to another advantageous embodiment, longitudinal connectors are not arranged within the surface area of the vessel branch. Expressed another way, only support braces are provided within the surface area of the vessel branch, for example, with their V-shaped support sections. By omitting the longitudinal connector, the mass of the edge elements is likewise reduced. A branch expansion is further simplified, thus, however, the radial force is Petition 870210105768, dated 11 / 16 / 2021, page 21 / 37 13 / 19 maintained.
[0041] According to another advantageous embodiment, within the vessel branch surface area and / or adjacent to the vessel branch surface area, one or more X-ray markers are arranged. The X-ray markers may contain a radiopaque material, for example, tantalum. The radiopaque material may be held in a grommet-shaped structure of the edge elements. In particular, four X-ray markers may be provided, which are arranged respectively at equal distances on the boundary of the vessel branch surface area. By means of X-ray markers arranged in this manner, the correct positioning of the stent or the vessel branch surface area in a vessel branch under X-ray observation is significantly simplified.
[0042] According to another advantageous embodiment, the edge elements are provided with a drug, at least in sections, the drug being released by the stent preferably over a specified time interval. The drug may have an antiproliferative effect to prevent the stent from becoming covered with tissue. For example, antiproliferative drugs from the Limus group, statins, P2Y12 antagonists or thrombin antagonists may be used.
[0043] According to another advantageous embodiment, the edge elements have a wall thickness of at most 4%, preferably at most 2%, more preferably at most 1.5%, of the second cross-sectional diameter. The width of the edge elements, i.e., the dimension seen in the circumferential direction, can Petition 870210105768, dated 11 / 16 / 2021, p. 22 / 37 14 / 19 preferably exhibit a maximum of 4%, more preferably a maximum of 2%, particularly preferably a maximum of 1.7%, of the second cross-sectional diameter. The edge elements may have, for example, a width of 105 to 120 μm and a wall thickness of 90 to 115 μm.
[0044] Thus, the stent may include edge elements that are, for example, 25 to 40% narrower and / or thinner than the common edge elements of absorbable PLLA stents. Through the particularly thin and narrow edge elements, the risk of thrombosis is further avoided, making it more difficult for blood platelets to accumulate.
[0045] Specifically, regarding the stent, it could be a coronary stent whose second cross-sectional diameter is, for example, a maximum of 2 mm or 4 mm.
[0046] Another object of the invention is a stent for transluminal implantation in hollow organs, particularly in blood vessels, ureters, esophagus, colon, duodenum or biliary tract, with an essentially tubular body, extending along an axial direction and convertible from a compressed state with a first cross-sectional diameter to an expanded state with a second enlarged cross-sectional diameter. The stent comprises a large number of cells defined by rib-like edge elements formed by the tubular body. The edge elements comprise at least one annular support strut that circulates around the axial direction, with a longitudinal connector applied to the support strut joining the support strut to at least one other support strut. The stent is distinguished by the fact that within a predefined area Petition 870210105768, dated 11 / 16 / 2021, page 23 / 37 No longitudinal connectors are arranged on 15 / 19 of the vessel branching surface.
[0047] By omitting the longitudinal connector, the mass of the edge elements is reduced and branching expansion is simplified, as mentioned above. In other words, within the surface area of the vessel branch, only support braces are provided, for example, with V-shaped support sections.
[0048] The surface area of the vessel branching may be the size of an artery or vein that empties into a blood vessel supported by the stent, in the stent area.
[0049] According to one embodiment, within the area of the vessel branching surface and / or adjacent to the area of the vessel branching surface, one or more X-ray markers or position markers are placed.
[0050] According to one embodiment, within the predefined area of the vessel branching surface, the edge elements have a lower mass than the edge elements in another area of the same size, the lower mass being achieved, for example, by thinner edge elements.
[0051] The statements made in this document for the first stent mentioned apply accordingly to the disclosed stent, this applies particularly to the advantages and preferred embodiments.
[0052] The invention is described herein by way of pure example with reference to the accompanying drawings. It shows: Figure 1 shows an external view of a stent in the state. Petition 870210105768, dated 11 / 16 / 2021, page 24 / 37 16 / 19 expanded; Figure 2 shows an external view of the stent from Figure 1, with the stent in an expanded state; Figure 3 shows the stent from Figure 1 in a compressed state; and Figure 4 shows an area of the branching vessel surface of the stent.
[0053] Figure 1 shows a partial view of a stent 10 in an expanded state with a second cross-sectional diameter, which corresponds to the nominal diameter of the stent 10. The stent 10 comprises a tubular body 12 extending along an axial direction A. The Figures show the stent 10 from a vertical viewing direction relative to the axial direction A. The stent 10 is formed by a plurality of edge elements 14 that together form a grid structure. The stent 10 extends to the left and right of the partial section shown in Figure 1.
[0054] Part of the edge elements 14 forms annular support braces 16 that enclose the axial direction A. The support braces 16 comprise several V-shaped support sections 18, which are arranged one behind the other, so that the support braces 16 have a zigzag-shaped structure in the circumferential direction. Each V-shaped support section 18 comprises two legs 20 between which a rib angle 22 is defined. In the example embodiment shown, the rib angle 22 is between, for example, 105° and 110°.
[0055] In the rib angle area 22 the support struts are joined together by means of longitudinal connectors 24, where only every second support section 18 is coupled to a longitudinal connector 24 in the circumferential direction. Petition 870210105768, dated 11 / 16 / 2021, page 25 / 37 17 / 19 Viewed from a circumferential direction, the longitudinal connectors 24 are applied, respectively alternately, on opposite sides of the support brace 16.
[0056] The zigzag shape of the support braces 16 is selected in such a way that the adjacent support braces 16 run, for example, parallel, i.e., not displaced or twisted to each other. This means that the connection positions of respectively two legs 20 of different support braces 16 run respectively slightly in a straight line, wherein, along the straight line, the rib angles 22 are arranged, respectively, on the same side of the support braces 16.
[0057] The stent 10 shown is made from a bioabsorbable material containing 97% zinc (Zn) and 3% silver (Ag). This zinc-silver alloy makes it possible to achieve the larger rib angle 22 shown, without the risk of rupture of one of the edge elements 14.
[0058] As shown in Figure 2, it is even possible to temporarily bring the stent to an over-expanded state in which the cross-sectional diameter is at least 7 to 20% larger than the second cross-sectional diameter mentioned above. Such a state is shown in Figure 2. As represented in Figure 2, in this state, the rib angle 22 can be greater than 120°.
[0059] In turn, Figure 3 shows the stent 10 in a compressed state with a first cross-sectional diameter. In this state, the legs 20 are approximately parallel, such that the rib angle 20 does not exist or is close to 0°.
[0060] Figure 4 finally shows another partial section. Petition 870210105768, dated 11 / 16 / 2021, page 26 / 37 18 / 19 of stent 10, as shown in Figures 1 to 3. Figure 4 shows a partial section of stent 10 with a slightly circular area of the branching surface of vessel 28 in top view.
[0061] The support struts 16 within the vessel branching surface area 28 are made approximately 25% thinner than in the normal stent 10. Furthermore, within the vessel branching surface area 28 there is no longitudinal connector 24, which is indicated by the (non-existent) longitudinal connector 24 shown in dashed lines.
[0062] It is understood that the support struts 16, which run through the vessel branching surface area 28, are coupled by longitudinal connectors 24 disposed outside the vessel branching surface area 28. These are not shown in Figure 4.Dispensing with the longitudinal connectors 24 and the thinner embodiment of the support struts 16 leads to a simpler dilation capacity of the stent in the range of the vessel branching surface area 28, such that the support struts 16 in the area of a vessel branch can be bent outwards, i.e., they can be bent at the edge of the vessel branching surface area 28, to enhance, for example, the blood flow running through the vessel branch.
[0063] In the area of the dispensed longitudinal connectors 24, four circular or elliptical position markers 26 are applied to the support struts 16. The position markers facilitate the placement of the stent 10 on the catheter (not shown). List of numerical references
[0064] Petition 870210105768, dated 11 / 16 / 2021, page 27 / 37 19 / 19 stent tubular body edge element support brace V-shaped support section side rib angle longitudinal connector position marker vessel branch surface area axial direction Petition 870210105768, dated 11 / 16 / 2021, pp. 28 / 37
Claims
1 / 3 CLAIMS 1. STENT (10) for transluminal implantation in hollow organs, particularly in blood vessels, ureters, esophagus, colon, duodenum or biliary tract, with a tubular body extending along an axial direction (A) and convertible from a compressed state with a first cross-sectional diameter to an expanded state with a second enlarged cross-sectional diameter, wherein the stent (10) comprises a large number of cells defined by rib-type edge elements (14) forming the tubular body and comprising a bioabsorbable material comprising zinc, wherein the edge elements (14) comprise one or more support struts (16) running annularly around the axial direction (A), characterized in that the support strut (16) has one or more V-shaped support sections (18),A longitudinal connector (24) is joined to the support strut (16) in the region of a rib angle (22) of the V-shaped support section (18) and connects the support strut (16) and the rib angle (22) of the V-shaped support section (18) is 90° to 150°, when the stent (10) has the second cross-sectional diameter.
2. STENT (10), according to claim 1, characterized in that the rib angle (22) has an angle of 100° to 130°.
3. STENT (10), according to claim 1, characterized in that the bioabsorbable material consists of zinc and silver, wherein the bioabsorbable material contains 90.0 to 99.95% by mass of zinc and 0.05 to 10.0% by mass of silver.
4. STENT (10), according to any one of claims 1 to 3, characterized in that the support braces (16) comprise several V-shaped support sections (18), which have, respectively, rib angles (22) in the range mentioned above, so that Petition 870260051076, dated 05 / 28 / 2026, page 7 / 15 2 / 3 results, in one or more areas, in a zigzag shape of the support brace (16).
5. STENT (10), according to any one of claims 1 to 4, characterized in that the support strut (16) runs radially around the axial direction (A), such that the axial direction forms a normal vector in the plane defined by the support strut (16).
6. STENT (10), according to any one of claims 1 to 5, characterized in that the stent (10) can be enlarged to a third cross-sectional diameter, which is larger than the second cross-sectional diameter, wherein the rib angle (22) widens by 120° or more when the stent (10) has the third cross-sectional diameter.
7. STENT (10), according to any one of claims 1 to 6, characterized in that within a predefined area of the vessel branching surface (28), the edge elements (14) have a lower mass than the edge elements (14) in another surface area of the same size, the lower mass being achieved by thinner edge elements (14).
8. STENT (10), according to claim 7, characterized in that within the surface area of the vessel branch (28) there are no longitudinal connectors (24).
9. STENT (10), according to any one of claims 7 or 8, characterized in that within the area of the branching surface of the vessel (28) and / or adjacent to the area of the branching surface of the vessel are arranged one or more X-ray markers.
10. STENT (10), according to any one of claims 1 to 9, characterized in that edge elements (14) are provided with a drug in one or more areas.
11. STENT (10), according to any one of claims 1 to 10, characterized in that the edge elements (14) have a wall thickness of at most 4% of the second cross-sectional shear diameter. Petition 870260051076, dated 05 / 28 / 2026, page 8 / 15 3 / 3 12. STENT (10) for transluminal implantation in hollow organs, particularly in blood vessels, ureters, esophagus, colon, duodenum or biliary tract, with a tubular body extending along an axial direction (A) and convertible from a compressed state with a first cross-sectional diameter to an expanded state with a second enlarged cross-sectional diameter, wherein the stent (10) comprises a large number of cells defined by rib-type edge elements (14) forming the tubular body and comprising a bioabsorbable material comprising zinc, wherein the edge elements (14) comprise one or more support struts (16) running annularly around the axial direction (A), wherein a longitudinal connector (24) is applied to the support strut (16), which joins the support strut (16) to one or more other support struts (16),characterized by the fact that within a predefined area of the branching surface of the vessel (28) no longitudinal connectors (24) are arranged, and the support braces 16 extend through the area of the branching surface of the vessel 28, but are not interrupted therein.
13. STENT (10), according to claim 12, characterized in that within the area of the branching surface of the vessel (28) and / or adjacent to the area of the branching surface of the vessel are arranged one or more X-ray markers or position markers (26).
14. STENT (10), according to any one of claims 12 or 13, characterized in that within a predefined area of the vessel branch surface (28), the edge elements (14) have a smaller mass than the edge elements (14) in another surface area of the same size, the smaller mass being achieved by thinner edge elements (14). Petition 870260051076, dated 05 / 28 / 2026, page 9 / 15