Dental cream containing minerals that have lost electrons, and method for manufacturing a dental cream
Patent Information
- Application Number
- BR112021026657
- Authority / Receiving Office
- BR · BR
- Patent Type
- Patents
- Current Assignee / Owner
- Publication Date
- 2026-08-11
Smart Images
Figure 00000015_0000
Abstract
Description
/ 12 Toothpaste containing minerals that have lost electrons, and a method for manufacturing toothpaste [Technical Field]
[001] The present invention relates to a toothpaste for preventing tooth sensitivity to cold and periodontal disease and a method of manufacturing the same, and more specifically to a toothpaste for preventing tooth sensitivity to cold and periodontal disease and a method of manufacturing the same using a toothpaste containing electron-losing minerals, wherein a toothpaste containing electron-losing minerals is used, in which the toothpaste has excellent therapeutic and preventive effects on various types of oral diseases, since the principle is applied to the toothpaste that electron-losing minerals (metallic) tend to take electrons from other atoms to become stabilized, i.e., covalently bonded or coordinately bonded.
[002] In particular, the present invention relates to a toothpaste for preventing tooth sensitivity to cold and periodontal disease and a method of manufacturing the same using a toothpaste containing electron-losing minerals, wherein when various (metallic) minerals extracted from food lose electrons and are added to a toothpaste composition, the electron-losing (metallic) minerals are covalently or coordinately bonded to a worn and damaged tooth surface, so that it not only forms a strong metallic film on the teeth, but also covalently bonds to the dentinal tubule, resulting in an excellent sealing effect, so that it can relieve irritation in sensitive teeth, such as a toothache, in a short period of time, and since teeth that may be gradually worn and damaged with use are coated (plated) with minerals (Fe, Cu, Zn, etc.).increasingly dense, painful teeth can be healed in a short period of time, worn teeth or. Petition 870210121373, dated 12 / 28 / 2021, p. 8 / 22 / 12 damaged teeth can be restored and plaque and tartar can be removed because toothpaste can covalently bind to plaque and tartar.
[003] Furthermore, the present invention relates to a toothpaste for preventing tooth sensitivity to cold and periodontal diseases and a method of manufacturing the same, using a toothpaste containing electron-losing minerals, wherein the strong alkalinity of the electron-losing minerals can change the environment into an alkaline environment where organisms causing gum disease, tooth decay and halitosis growing in an acidified oral environment cannot survive, thus preventing the growth of various bacteria without any side effects and representing high efficacy in the cure and prevention of various periodontal diseases. [Fundamentals of the Technique]
[004] Toothpaste is a quasi-drug used when brushing the surface of the teeth and is mainly used for whitening, sterilizing, and interdental cleaning purposes. For this purpose, toothpaste contains ingredients such as abrasives, wetting agents, foaming agents, sweeteners, and the like.
[005] This toothpaste is being developed to have several functions for oral health, in addition to simply cleaning teeth and, for example, having a function to prevent tooth hypersensitivity (such as the phenomenon of tooth sensitivity to cold).
[006] Tooth hypersensitivity is a sensation of sensitivity when the tooth enamel is worn or damaged and the dentin is exposed and comes into contact with cold air or stimulating foods, and its symptoms can range from mild to intense and persistent pain.
[007] The severity of symptoms varies depending on the degree of exposure of the dentinal tubules. A tooth can be divided into layers of Petition 870210121373, dated 12 / 28 / 2021, page 9 / 22 / 12. Enamel on the outer surface, dentin just below the enamel layer, pulp where nerves and blood vessels are distributed, and gingival tissue that protects the teeth. However, if the enamel layer is damaged due to incorrect brushing, gum disease, or tooth decay, or when the dentin is exposed due to a depression in the gum, external stimulation is transmitted to the tooth nerve through the dentinal tubule, causing short but intense and sharp pain. In particular, nowadays, symptoms of tooth sensitivity to cold are increasing even among young people, and treatment is necessary from the initial stage.
[008] Meanwhile, in order to prevent tooth decay, fluoride at a concentration of 0.05 to 0.1% w / v is frequently used in toothpaste or mouthwash, however, recent reports show that prolonged and repeated use of fluoride compounds may promote gum inflammation, although the use of fluoride compounds in toothpaste or mouthwash may prevent tooth decay.
[009] In order to resolve the above disadvantages, several toothpastes have been developed, examples of which include Patent Documents 1 to 3.
[0010] Korean Patent Registration No. 10-1150309, which is Patent Document 1, describes a method for manufacturing herbal extracts to prevent periodontal disease and dental calculus that includes the steps of i) extracting 20 to 25% by weight of barberry root, 20 to 25% by weight of phalanges, 15 to 20% by weight of tribulus terrestris, 30 to 35% by weight of taraxacum herb and 4 to 7% by weight of licorice with alkaline ionized water with a pH of 7 to 10 as a solvent at 40 to 85°C for 1 to 5 hours; and ii) adding 10 to 30 g of calcium oxide based on 100 ml of the extracted filtrate, stirring and leaving at 4 to 5°C for 12 to 24 hours to filter the supernatant.
[0011] Korean Unexamined Patent Publication No. 10-2017 Petition 870210121373, dated 12 / 28 / 2021, page 10 / 22 / 12 Patent Document 2, number 0029106, describes a method for preparing an herbal extract fermented by lactic acid bacteria to prevent and improve dental caries, periodontal disease, and halitosis, which includes the steps of (a) preparing a fermentation raw material by drying and pulverizing herbs and then sterilizing the herbs at high temperature; (b) obtaining a fermented product by inoculation and fermentation of plant lactic acid bacteria in the fermentation raw material obtained in the above step; (c) centrifuging the fermented product obtained in the previous step to obtain a fermented broth; (d) extracting the fermented broth obtained in the previous step with an extraction solvent to obtain a fermented extract; and (e) filtering the fermented extract obtained in the previous step with filter paper.
[0012] Korean Patent No. 10-1818530, which is Patent Document 3, describes a toothpaste composition comprising 2 to 10 parts by weight of lettuce powder, 2 to 10 parts by weight of oat powder, 1 to 5 parts by weight of kaolin clay, 0.5 to 2 parts by weight of turmeric powder, 0.9 parts by weight of houttuynia cordata powder and 0.005 to 0.1 parts by weight of sulfur powder.
[0013] However, although conventional toothpastes have several functionalities, there is the disadvantage that the use of fluoride promotes inflammation and has limitations in reducing tooth decay. [Description] [Technical Problem]
[0014] The present invention was developed to solve the above problems of the prior art, and one objective of the present invention is to provide a toothpaste composition that can fundamentally prevent periodontal disease by blocking or coating worn or damaged dentinal tubules through the covalent bonding of electron-losing minerals to alleviate tooth hypersensitivity to cold, and another objective of the present invention is to provide a toothpaste to prevent the Petition 870210121373, dated 12 / 28 / 2021, page 11 / 22 / 12 sensitivity of teeth to cold and periodontal diseases, and a manufacturing method for the same, which can inhibit the proliferation of Streptococcus mutans bacteria, which are bacteria that cause tooth decay and can improve the antibacterial effect.
[0015] Furthermore, another objective of the present invention is to provide a toothpaste to prevent tooth sensitivity to cold and periodontal diseases, and a method of manufacturing the same, which does not use fluoride and is free of saccharin and preservatives, therefore, so that it not only improves safety for users who are sensitive to chemical components, but also has the effect of curing and preventing various oral and gingival diseases. [Technical Solution]
[0016] In order to achieve the above objectives, the present invention provides a toothpaste containing electron-losing minerals, wherein 0.5 to 15% of the electron-losing minerals are added based on the total weight of a toothpaste composition.
[0017] They are preferably provided with at least three types of minerals.
[0018] A method for manufacturing a toothpaste containing electron-losing minerals includes: washing the minerals; ionizing to prepare the electron-losing minerals; pulverizing the electron-losing minerals; mixing a composition by blending flavors, electron-losing minerals, and organic acid into a basic toothpaste material; preparing purified mineral water by mixing the pulverized electron-losing minerals with purified water; and aging by mixing the blended composition with the purified mineral water.
[0019] Preferably, 0.1 to 15% of electron-losing minerals are contained based on the total weight of a toothpaste composition.
[0020] Minerals that have lost electrons can be prepared Petition 870210121373, dated 12 / 28 / 2021, page 12 / 22 / 12 heating at least one of the foods and herbal medicines containing a large amount of minerals and materials containing minerals to 850°C or more for 15 minutes or more to cause the minerals to lose electrons.
[0021] Purified mineral water can be prepared by mixing 1 to 50% by weight of organic acid and 1 to 50% by weight of electron-losing minerals based on the total weight of the purified water.
[0022] The herbal medicine may be at least one of the following: bovine bone, osterea testa raw material, and cassia occidentalis raw material. [Beneficial Effects]
[0023] According to the toothpaste for preventing tooth sensitivity to cold and periodontal disease of the present invention, the mineral film can be formed on the teeth because the minerals that have lost electrons form a covalent bond or a coordination bond with electrons from other elements for the purpose of stabilization, so that the treatment and prevention effects for various oral diseases can be obtained by the film formed on the teeth.
[0024] In particular, the present invention not only forms a strong metallic film on the teeth, but also has a covalent bond to the dentinal tubules to seal the dentinal tubules so that it has the effect of relieving irritation of sensitive teeth, such as tooth sensitivity to cold, in a short period of time.
[0025] Furthermore, the present invention has the effect of inhibiting and preventing the growth of bacteria that cause gum disease, tooth decay, halitosis, etc., which survive in the oral cavity because the strong alkalinity of the electron-losing minerals can change the acidified oral environment into an alkaline environment. [Description of the drawings] Petition 870210121373, dated 12 / 28 / 2021, p. 13 / 22 / 12
[0026] Figure 1 is a block diagram to explain a method for manufacturing a toothpaste to prevent tooth sensitivity to cold and periodontal disease according to the present invention. [Best Mode] [Mode of invention]
[0027] Various modifications can be made to the present invention and the present invention may have several embodiments. Specific embodiments are illustrated in the drawings and will be described by means of the detailed description. However, this is not intended to limit the present invention to specific embodiments and it should be understood that all modifications, equivalents and substitutes may be within the spirit and scope of the present invention.
[0028] Similar reference numbers are used for similar components throughout the drawings. In the following description of the present invention, if it is determined that a detailed description of a known related technology might obscure the essence of the present invention, the detailed description thereof shall be omitted.
[0029] The present invention can provide a toothpaste capable of treating and preventing various oral and gingival diseases.
[0030] The toothpaste containing the electron-losing mineral according to the present invention is distinguished by 0.5 to 15% of the electron-losing minerals being added based on the total weight of the toothpaste composition.
[0031] When the amount of electron-losing minerals is 0.1% by weight or less, the coating effect on the tooth surface is insignificant, and when the amount of electron-losing minerals is 15% by weight or more, the alkalinity becomes too strong and there is a risk of the gums peeling.
[0032] Consequently, it is preferable to add minerals that have lost electrons within the above range and, ideally, it is added in Petition 870210121373, dated 12 / 28 / 2021, page 14 / 22 / 12 an amount of 3 to 9% by weight based on the total weight of the toothpaste.
[0033] In addition, the electron-losing minerals may be in powder form and, in this case, it is preferable that the particle diameter be in the range of 1.0 to 2.5 μm.
[0034] At least three types of minerals may be used, and the types of minerals may be at least one of foods and herbal medicines containing a large amount of minerals and materials containing minerals.
[0035] The herbal medicine containing the minerals may be at least one of bovine bone, an osterea testa raw material, and a cassia occidentalis raw material.
[0036] Electron-losing minerals can be prepared by heating a mineral raw material to 850°C or more for 15 minutes or more so that the mineral loses electrons.
[0037] As shown in Figure 1, the method for manufacturing a toothpaste containing electron-losing minerals includes: washing the minerals; ionizing to prepare the electron-losing minerals; pulverizing the electron-losing minerals; preparing a base composition by mixing flavors into a basic toothpaste material; preparing purified mineral water by mixing the pulverized electron-losing minerals with purified water; and aging by mixing a mixed composition with purified mineral water.
[0038] The toothpaste prepared as shown in Figure 1 is completed as a product by filling the toothpaste into a container.
[0039] Electron-losing minerals are added in an amount of 0.1 to 15% based on the total weight of the toothpaste composition, but as described above, the ideal mixing ratio is preferably 3 to 9% by weight based on the total weight of the toothpaste.
[0040] Minerals that have lost electrons can be prepared Petition 870210121373, of 12 / 28 / 2021, page 15 / 22 / 12 using at least one of the foods and herbal medicines that contain a large amount of minerals and materials containing minerals.
[0041] According to the method for producing electron-losing minerals, a raw material containing the minerals is heated to 850°C or more for 15 minutes or more to cause the minerals to lose electrons.
[0042] Purified mineral water can be prepared by mixing 1 to 50% by weight of an organic acid and 1 to 50% by weight of electron-losing minerals based on the total weight of the purified water.
[0043] Examples of the method for manufacturing toothpaste using the above method will be described below. <exemplo> 1. Materials and Methods
[0044] (1) The composition of the toothpaste contains a humectant (glycerin, sorbitol solution), a foaming agent (sodium lauryl sulfate), a sweetener (xylitol), an active ingredient (propolis), a fragrance (menthol), a solvent (purified water), a bleaching agent (titanium dioxide) and the basic materials that constitute the toothpaste were acquired commercially.
[0045] (2) The minerals that lost electrons were prepared by purchasing bovine bones, abalone and oysters.
[0046] (3) Preparation of electron-lost minerals - the raw materials from (2) were placed in an electric furnace and heated to 1250C for 25 minutes to cause the minerals to lose more than 93% of their electrons. After removing the raw materials, the raw materials were sprayed by a sprayer (Hallde SB-4, Sweden) for 10 minutes and 10% of the raw materials were stirred in distilled water (20C), and the resulting solution was treated with ozone for residual discoloration and odor removal. Petition 870210121373, dated 12 / 28 / 2021, p. 16 / 22 / 12
[0047] (4) Next, purified water, in which a large quantity of electron-losing minerals is dissolved, was prepared by adding 1 to 50% by weight of organic acids and 1 to 50% by weight of electron-losing minerals to the purified water (it is not necessary to use the prepared purified water and it can only be used when it is necessary to lower the pH and increase the content of electron-losing minerals). 2. Preparation of toothpaste containing electron-losing minerals Table 1: Composition ratio of the toothpaste containing electron-losing minerals No. Ingredient Name Example Comparison 1 Example 1 Example 2 Example 3 1 Precipitated Calcium Carbonate 37 25 25 15 2 Glycerin - 50 - - 3 Sorbitol 40 - 40 34 4 Xylitol 1.5 1.0 2.0 2.0 5 Sodium Pyrophosphate 2.5 0.48 2.0 3.0 6 Citric Acid 0.1 4.0 7 Sodium Carboxymethylcellulose 1.5 1.0 1.5 1.0 8 Tranexamic Acid 0.5 0.5 0.5 0.5 9 Flavor 1.0 1.5 1.0 1.0 10 Electron-Lost Minerals - 0.01 3.0 6.0 11 Purified Water (4) Residue Residue Waste Waste 12 Total 100 100 100 100
[0048] A toothpaste was prepared by mixing the components in the ratio of the composition as shown in Table 1 above. 3. Experiment for the purpose of removing halitosis.
[0049] After selecting 20 men and women who knew they had halitosis as subjects for a clinical trial, they ate the same types of food, and the degree of halitosis was quantified using a halimeter (model SB-17, USA). Then, people with mild halitosis (60 or less) and very strong halitosis (350 or more) were excluded from the trial, and then halitosis was measured in relation to five people belonging to the Comparative Examples and Examples groups, and the mean values were adjusted so that the mean values were similar between the two groups. For reproducibility purposes, the following day, the initial halitosis was measured in 20 men and women, 30 minutes and 60 minutes after the same meal. In Petition 870210121373, dated 12 / 28 / 2021, page 17 / 22 / 12 followed, after the provision of toothbrushes and toothpaste for each composition (Example), brushing was performed for 3 minutes in the same way and the final halitosis was measured after 30 minutes and 60 minutes. Table 2: Halitosis removal effect Treatment Group Baseline 30 minutes after meals 60 minutes after meals Example Comparison 1 200 150 170 Example 1 200 140 160 Example 2 210 134 145 Example 3 210 130 140
[0050] The value provided is the average value of two tests.
[0051] φ In Comparative Example 1, when 30 minutes and 60 minutes had passed after meals, the rate of halitosis removal decreased by 15-25% compared to the baseline.
[0052] @ Examples 1, 2 and 3 showed a decrease of about 26 to 35% compared to the baseline and, in particular, Example 3 showed the largest decrease with a decrease of 31 to 39%. 4. Gingivitis inhibition test
[0053] This test was conducted on 20 subjects in a relatively similar environment, and the primary oral examination was conducted for all subjects prior to the test to obtain a baseline. The test method was a simple blinded method, and the same cleaning agent and toothbrush were provided to all individuals during the 4-week residual effect removal period prior to the test.
[0054] In the test, the gingiva was divided into vestibular and lingual surfaces per tooth to calculate the average index value. Each gingivitis case was evaluated from 0 to 3 points according to the Silness-Loe marking pattern to obtain the gingival index of each tooth, after which the average degree of the gingival index of each entity was calculated, with the measurement for the test being performed a total of three times over a one-month interval. Petition 870210121373, dated 12 / 28 / 2021, page 18 / 22 / 12 Table 3: Comparison of gingivitis inhibition Treatment Group Baseline After 2 months After 4 months Example Comparison 1 0.63 0.59 0.60 Example 1 0.62 0.52 0.50 Example 2 0.61 0.45 0.43 Example 3 0.62 0.42 0.40
[0055] The value provided is the average value of two tests.
[0056] φ In Comparative Example 1, there was no significant change even after 2 to 4 months.
[0057] @ In the case of Examples 1, 2 and 3, there was a decrease of 8 to 33% after 2 months and 21 to 37% after 4 months.
[0058] @ Example 3 showed the greatest decrease. 5. Comparison test to reduce tooth sensitivity to cold
[0059] This test was conducted on 25 individuals with relatively identical tooth sensitivity to cold, and all individuals drank 9°C cold water 5 times before the test, and the degree of irritation was accurately measured to obtain the baseline.
[0060] In the test, all subjects received the same dental cleaning agent and the same standard toothbrush.
[0061] Tooth brushing was performed for 3 minutes in the morning and at night after meals, and after 1 month of use, the degree of irritation was measured. Table 4: Comparison of reduction in tooth sensitivity to cold. Treatment Group Baseline 1 month later After 2 months Example Comparison 1 100 98 97.5 Example 1 100 92 90 Example 2 100 15 10 Example 3 100 7 2
[0062] The value provided is the average of two tests.
[0063] φ In Comparative Example 1, there was no significant change even after 1 month and 2 months.
[0064] @ Examples 1, 2 and 3 showed a decrease of 8 to 93% compared to baseline after 1 month and a decrease of 10 to 98% after 2 months.
[0065] @ Example 3 showed the greatest decrease. Petition 870210121373, dated 12 / 28 / 2021, pages 19 / 22< / exemplo>
Claims
1 / 2 CLAIMS 1. Toothpaste containing electron-losing minerals, wherein 0.5 to 15% of the electron-losing minerals are added based on the total weight of a toothpaste composition, characterized in that: the electron-losing minerals are prepared by heating at least one of foods and herbal medicines containing a large quantity of minerals and mineral-containing materials to 1250°C or more to cause the minerals to lose electrons, and at least three types of minerals are used, and the herbal medicine containing the minerals is at least one bovine bone, one Osterea testa raw material and one Cassia occidentalis raw material.
2. Method for manufacturing a toothpaste containing electron-losing minerals as defined in claim 1, the method comprising: washing the minerals; ionizing to prepare the electron-losing minerals; pulverizing the electron-losing minerals; preparing a basic composition by mixing flavors to a toothpaste base material; preparing purified mineral water by mixing the pulverized electron-losing minerals with purified water; and aging by mixing a blended composition with the purified mineral water, characterized in that: the electron-losing minerals are prepared by heating at least one of foods and herbal medicines containing a large amount of minerals and mineral-containing materials to 1250°C or more to cause the minerals to lose electrons, and Petition 870250059179, dated 11 / 07 / 2025, p.17 / 20 2 / 2 at least three types of minerals are used, and the herbal medicine containing the minerals is at least one from bovine bone, one raw material from Osterea testa and one raw material from Cassia occidentals, and 0.5 to 15% of the electron-losing minerals are contained based on a total weight of a toothpaste composition.
3. Method according to claim 2, characterized in that the purified mineral water is prepared by mixing 1 to 50% by weight of organic acid and 1 to 50% by weight of electron-losing minerals based on a total weight of purified water. Petition 870250059179, dated 11 / 07 / 2025, p. 18 / 20