COMPOSIÇÕES DE HIGIENE PESSOAL

Abstract

Described herein is a viscosity control composition comprising a surfactant blend comprising a biosurfactant, an anionic surfactant, a zwitterionic surfactant comprising sodium lauroamphoacetate, a gum comprising carrageenan, and a liquid carrier.

Description

1 / 46 Personal Hygiene Compositions - Cross-reference to Related Orders

[0001] This application claims the benefit of priority of U.S. Patent Application No. 63 / 493,415, filed March 31, 2023, entitled Personal Care Compositions, the contents of which are incorporated herein in full for all purposes. FUNDAMENTALS OF THE INVENTION

[0002] Surfactants are used in personal care and household products to impart foaming properties. The use of surfactants also raises concerns about environmental influences and dermatological problems. While biosurfactants can be used for sustainability and milder interactions, they also have more complicated structures than conventional surfactants and pose a challenge in controlling the impact of biosurfactant micelle performance. Therefore, there is a need to improve these biosurfactants used in such cleaning liquids. SUMMARY

[0003] The present invention is directed to a viscosity control composition comprising a surfactant mixture comprising a biosurfactant; an anionic surfactant; a zwitterionic surfactant comprising sodium lauroamphoacetate; a gum comprising carrageenan; and a liquid carrier.

[0004] Other embodiments of the present invention include a viscosity control composition comprising: a surfactant mixture comprising a biosurfactant; an anionic surfactant; a zwitterionic surfactant; a gum comprising carrageenan; and a liquid carrier; wherein the anionic surfactant and the biosurfactant are present in a weight ratio ranging from about 1:20 to about 20:1; wherein the zwitterionic surfactant and the biosurfactant are present Petition 870250084445, dated 09 / 19 / 2025, p. 16 / 73 2 / 46 in a weight ratio ranging from about 1:10 to about 10:1; and wherein the gum and biosurfactant are present in a weight ratio ranging from about 1:30 to about 30:1.

[0005] Other embodiments of the present invention include a viscosity control composition comprising: a rhamnolipid; sodium lauroyl sarcosinate; sodium lauroamphoacetate; carrageenan; and a liquid carrier.

[0006] Other embodiments of the present invention include a personal hygiene composition comprising: the viscosity control composition mentioned above; and a personal hygiene ingredient; wherein the personal hygiene composition is a liquid hand soap, shower gel, shampoo, conditioner, liquid body soap, facial cleanser or skin cleanser.

[0007] Other embodiments of the present invention include a method for manufacturing a viscosity-controlled personal hygiene product, the method comprising: mixing a viscosity-controlling composition, as described herein, with a personal hygiene additive to form a personal hygiene composition; adding a predetermined volume of the personal hygiene composition to a container to form the personal hygiene product.

[0008] Other areas of applicability of the present invention will become apparent from the detailed description provided below. It should be understood that the detailed description and specific examples, while indicating the preferred embodiment of the invention, are intended for illustrative purposes only and are not intended to limit the scope of the invention.

[0009] A list of examples of non-limiting modalities is provided below: Petition 870250084445, dated 09 / 19 / 2025, page 17 / 73 3 / 46

[0010] According to embodiment 1, a viscosity control composition is provided comprising: a mixture of surfactants comprising: a biosurfactant; an anionic surfactant; a zwitterionic surfactant comprising sodium lauroamphoacetate; a gum comprising carrageenan; and a liquid carrier.

[0011] According to embodiment 2, a viscosity control composition is provided according to embodiment 1, wherein the biosurfactant comprises rhamnolipid.

[0012] According to embodiment 3, a viscosity control composition is provided according to any of embodiments 1 to 2, wherein the biosurfactant is present in an amount ranging from about 0.01% by weight to about 13% by weight based on the weight of the viscosity control composition.

[0013] According to embodiment 4, a viscosity control composition is provided according to any of embodiments 1 to 3, wherein the anionic surfactant comprises an amine-containing compound.

[0014] According to embodiment 5, a viscosity control composition is provided according to any of embodiments 1 to 4, wherein the anionic surfactant comprises sodium lauroyl sarcosinate.

[0015] According to embodiment 6, a viscosity control composition is provided according to any of embodiments 1 to 5, wherein the anionic surfactant is present in an amount ranging from about 0.1% by weight to about 13.0% by weight based on the weight of the viscosity control composition. Petition 870250084445, dated 09 / 19 / 2025, page 18 / 73 4 / 46

[0016] According to embodiment 7, a viscosity control composition is provided according to any of embodiments 1 to 6, wherein the zwitterionic surfactant is present in an amount ranging from about 1.0% by weight to about 24.0% by weight based on the weight of the viscosity control composition.

[0017] According to embodiment 8, a viscosity control composition is provided according to any of embodiments 1 to 7, wherein the gum is present in an amount ranging from about 0.1% by weight to about 5.0% by weight based on the weight of the viscosity control composition.

[0018] According to embodiment 9, a viscosity control composition is provided according to any of embodiments 1 to 8, wherein the gum consists of carrageenan.

[0019] According to embodiment 10, a viscosity control composition is provided according to any of embodiments 1 to 9, wherein the anionic surfactant and the biosurfactant are present in a weight ratio ranging from about 0.6:1 to about 2:1.

[0020] According to embodiment 11, a viscosity control composition is provided according to any of embodiments 1 to 10, wherein the zwitterionic surfactant and the biosurfactant are present in a weight ratio ranging from about 5:1 to about 10:1.

[0021] According to embodiment 12, a viscosity control composition is provided according to any of embodiments 1 to 11, wherein the gum and biosurfactant are present in a weight ratio ranging from about 0.5:1 to about 2:1. Petition 870250084445, dated 09 / 19 / 2025, p. 19 / 73 5 / 46

[0022] According to embodiment 13, a viscosity control composition is provided according to any of embodiments 1 to 12, wherein the liquid carrier comprises water.

[0023] According to embodiment 14, a viscosity control composition is provided according to any of embodiments 1 to 13, wherein the surfactant mixture, gum and liquid carrier total about 100% by weight of the viscosity control composition.

[0024] According to embodiment 15, a viscosity control composition is provided comprising: a mixture of surfactants comprising: a biosurfactant; an anionic surfactant; a zwitterionic surfactant; a gum comprising carrageenan; and a liquid carrier; wherein the anionic surfactant and the biosurfactant are present in a weight ratio ranging from about 0.6:1 to about 2:1; wherein the zwitterionic surfactant and the biosurfactant are present in a weight ratio ranging from about 5:1 to about 10:1; and wherein the gum and the biosurfactant are present in a weight ratio ranging from about 0.5:1 to about 2:1.

[0025] According to embodiment 16, a viscosity control composition is provided according to embodiment 15, wherein the biosurfactant comprises rhamnolipid.

[0026] According to embodiment 17, a viscosity control composition is provided according to any of embodiments 15 to 16, wherein the biosurfactant is present in a Petition 870250084445, dated 09 / 19 / 2025, p. 20 / 73 6 / 46 quantity that varies from about 0.1% by weight to about 3% by weight based on the weight of the viscosity control composition.

[0027] According to embodiment 18, a viscosity control composition is provided according to any of embodiments 15 to 17, wherein the anionic surfactant comprises an amine-containing compound.

[0028] According to embodiment 19, a viscosity control composition is provided according to any of embodiments 15 to 18, wherein the anionic surfactant comprises sodium lauroyl sarcosinate.

[0029] According to embodiment 20, a viscosity control composition is provided according to any of embodiments 15 to 19, wherein the anionic surfactant is present in an amount ranging from about 0.5% by weight to about 3.5% by weight based on the weight of the viscosity control composition.

[0030] According to embodiment 21, a viscosity control composition is provided according to any of embodiments 15 to 20, wherein the zwitterionic surfactant comprises sodium lauroamphoacetate.

[0031] According to embodiment 22, a viscosity control composition is provided according to any of embodiments 15 to 21, wherein the zwitterionic surfactant is present in an amount ranging from about 2.0% by weight to about 12.0% by weight based on the weight of the viscosity control composition.

[0032] According to embodiment 23, a viscosity control composition is provided according to any of embodiments 15 to 22, wherein the gum is present in an amount ranging from about 0.1% by weight to about 5.0% by weight based on the weight of the viscosity control composition. Petition 870250084445, dated 09 / 19 / 2025, page 21 / 73 7 / 46

[0033] According to embodiment 24, a viscosity control composition is provided according to any of embodiments 15 to 23, wherein the gum consists of carrageenan.

[0034] According to embodiment 25, a viscosity control composition is provided according to any of embodiments 15 to 24, wherein the liquid carrier comprises water.

[0035] According to embodiment 26, a viscosity control composition is provided according to any of embodiments 15 to 25, wherein the surfactant mixture, gum and liquid carrier total about 100% by weight of the viscosity control composition.

[0036] According to embodiment 27, a viscosity control composition is provided comprising: a rhamnolipid; sodium lauroyl sarcosinate; sodium lauroamphoacetate; carrageenan; and a liquid carrier.

[0037] According to embodiment 28, a viscosity control composition is provided according to embodiment 27, wherein rhamnolipid is present in an amount ranging from about 0.1% by weight to about 3% by weight based on the weight of the viscosity control composition.

[0038] According to embodiment 29, a viscosity control composition is provided according to any of embodiments 27 to 28, wherein sodium lauroyl sarcosinate is present in an amount ranging from about 0.5% by weight to about 3.5% by weight based on the weight of the viscosity control composition. Petition 870250084445, dated 09 / 19 / 2025, page 22 / 73 8 / 46

[0039] According to embodiment 30, a viscosity control composition is provided according to any of embodiments 27 to 29, wherein sodium lauroamphoacetate is present in an amount ranging from about 2.0% by weight to about 12.0% by weight based on the weight of the viscosity control composition.

[0040] According to embodiment 31, a viscosity control composition is provided according to any of embodiments 27 to 30, wherein carrageenan is present in an amount ranging from about 0.1% by weight to about 5.0% by weight based on the weight of the viscosity control composition.

[0041] According to embodiment 32, a viscosity control composition is provided according to any of embodiments 27 to 31, wherein the liquid carrier comprises water.

[0042] According to embodiment 33, a viscosity control composition is provided according to any of embodiments 27 to 32, wherein rhamnolipid, sodium lauroyl sarcosinate, sodium lauroamphoacetate, carrageenan and liquid carrier total about 100% by weight of the viscosity control composition.

[0043] According to embodiment 34, a personal hygiene composition is provided comprising: the viscosity control composition according to any of the embodiments 1 to 33; and a personal hygiene ingredient; where the personal hygiene product is a hygienic soap, shower gel, shampoo, conditioner, liquid soap, or skin cleanser.

[0044] According to embodiment 35, a viscosity control composition is provided according to embodiment 34, wherein the personal hygiene ingredient comprises one or more of the following: colorant, fragrance and combinations thereof. Petition 870250084445, dated 09 / 19 / 2025, page 23 / 73 9 / 46

[0045] According to embodiment 36, a method is provided for manufacturing a personal hygiene product with viscosity control, the method comprising: Mixing a viscosity control composition according to any of embodiments 1 to 33 with a personal hygiene ingredient to form a personal hygiene composition; and adding a predetermined volume of the personal hygiene composition to a container to form the personal hygiene product. DETAILED DESCRIPTION

[0046] The following description of preferred embodiments is merely illustrative in nature and is in no way intended to limit the invention, its application or uses.

[0047] As used throughout the document, ranges are used as shorthand to describe each and every value that is within the range. Any value within the range can be selected as the end of the range. In addition, all references cited in this document are incorporated herein by reference in their entirety. In the event of a conflict between a definition in this disclosure and a definition in a cited reference, the definition in this disclosure shall prevail.

[0048] Unless otherwise specified, all percentages and quantities expressed in this document and elsewhere in the descriptive report shall be understood as referring to percentages by weight. The quantities provided are based on the active weight of the material.

[0049] The description of illustrative embodiments according to the principles of the present invention should be read in connection with the accompanying figures, which should be considered an integral part of the entire written description. In the description of embodiments of the invention, disclosed Petition 870250084445, dated 09 / 19 / 2025, p. 24 / 73 10 / 46 in this document, any reference to meaning or direction is for convenience of description only and is not intended in any way to limit the scope of the present invention.

[0050] Terms such as linked, fixed, connected, coupled, interconnected and the like refer to a relationship in which structures are attached or linked to each other, directly or indirectly, through intervening structures, as well as movable or rigid links or relationships, unless expressly described otherwise. Furthermore, the features and benefits of the invention are illustrated by reference to the exemplary embodiments. Thus, the invention should not be expressly limited to these exemplary embodiments which illustrate some possible and non-limiting combination of features that may exist individually or in other combinations of features; the scope of the invention being defined by the appended claims.

[0051] Unless otherwise specified, all percentages and quantities expressed in this document and elsewhere in the descriptive report shall be understood as referring to percentages by weight. The quantities provided are based on the active weight of the material. In accordance with this application, the term “approximately” means + / - 10% of the reference value. In accordance with this application, the term substantially exempt means less than approximately 0.1% by weight based on the total reference value.

[0052] As used herein, the use of a compound comprising several isomers or stereoisomers includes all isomeric forms of that compound. When referring to chemical structures and names, the symbols “C”, “H”, and “O” mean carbon, hydrogen, and oxygen, respectively. The symbols “-”, “=”, and “=” mean single bond, double bond, and triple bond, respectively. For readability purposes, chemical functional groups are in their adjective form; for each of the Petition 870250084445, dated 09 / 19 / 2025, p. 25 / 73 11 / 46 adjectives, the word “group” is assumed. For example, the adjective “alkyl” without subsequent nouns should be read as “an alkyl group”.

[0053] Any member of a species list that is used to exemplify or define a genus may be mutually different from, overlapping with, a subset of, equivalent to, nearly equal to, or identical to any other member of the species list. Furthermore, unless explicitly stated, such as when citing a Markush group, the list of species that define or exemplify the genus is open-ended, and it is given that there may be other species that define or exemplify the genus as well as or better than any other species listed.

[0054] All components and elements presented positively in this disclosure may be excluded negatively from the claims. In other words, the personal care compositions of this disclosure may be free or essentially free of all components and elements cited positively throughout this disclosure. In some cases, the personal care compositions of this disclosure may be substantially free of non-incidental amounts of the ingredient(s) or compound(s) described herein. A non-incidental amount of an ingredient or compound is the amount of that ingredient or compound that is added by itself to the personal care composition.For example, a personal care composition may be substantially free of a non-incidental amount of an ingredient or compound, although such ingredient(s) or compound(s) may be present as part of a raw material that is included as a mixture of two or more compounds.

[0055] Some of the various categories of components identified may overlap. In such cases where overlap may exist and the personal hygiene composition includes both components (or the composition includes more than two overlapping components), one Petition 870250084445, dated 09 / 19 / 2025, p. 26 / 73 12 / 46 overlapping compound does not represent more than one component. For example, caprylyl glycol can be characterized as both a humectant and a preservative. If a specific composition for personal care includes a humectant and a preservative, caprylyl glycol will serve only as a humectant or a preservative – not both.

[0056] As used herein, the terms “composition” and “formulation” may be used interchangeably within the descriptive report.

[0057] Aspects of the invention are directed to the viscosity control composition. Aspects of the invention are further directed to the personal hygiene composition comprising the viscosity control composition.

[0058] The viscosity control composition may comprise a mixture of surfactants. The surfactant mixture may comprise 2 or more surfactants, for example, 3, 4, 5, 6, 7, 8, 9, 10 surfactants, or a range formed from them. For example, the oral hygiene composition may comprise 2 to 6, 2 to 5, 2 to 4, 2 or 3; 3 to 6, or 3 or 4 surfactants. The surfactant mixture may comprise a first surfactant, a second surfactant and a third surfactant. In some embodiments, the viscosity control composition comprises a surfactant mixture of two or more surfactants, wherein at least one surfactant is a biosurfactant.For example, the surfactant mixture may comprise two or more surfactants, with at least one of the surfactants being a biosurfactant and at least one of the surfactants being an anionic surfactant (e.g., a non-sulfate-based anionic surfactant), an amphoteric surfactant, a nonionic surfactant, or a combination of two or more of these. The viscosity control composition may comprise a thickening agent. The viscosity control composition may comprise a liquid carrier. Petition 870250084445, dated 09 / 19 / 2025, p. 27 / 73 13 / 46

[0059] The first surfactant in the surfactant mixture may comprise a biosurfactant. The term “biosurfactant” may refer to a compound generally of biological origin. In some embodiments, the biosurfactant may be produced from fermentation. Thus, the biosurfactant may be formed from raw materials that include sugars or sugars and glycerides and / or fatty acids. Biosurfactants do not undergo chemical reactions like synthetic glycolipids, for example, alkyl polyglycosides (APG). Biosurfactants may be found in living organisms or arise in the cultivation of various microorganisms, such as fungi, yeasts, algae, viruses, bacteria, or enzymes.

[0060] Biosurfactants may comprise rhamnolipids, glycolipids, sophorolipids, trehaloselipids, cellobioselipids, and mixtures thereof. Biosurfactants can be obtained directly from natural raw materials through microbiological processes, while the production of synthetic glycolipids generally requires additional chemical steps, such as the reduction of fatty acids to fatty alcohol. Due to the biological modification of the sugar moiety, glycolipid biosurfactants exhibit special properties, for example, as is known in the art, good fat-dissolving power. The structure of biosurfactants and the chain lengths of the hydrophobic moiety vary depending on the microorganism or substrate used.

[0061] Non-limiting examples of rhamnolipids include compounds with formula (I): Petition 870250084445, dated 09 / 19 / 2025, p. 28 / 73 14 / 46

[0062] where a is 1 or 2; b is 1 or 2, n is 2 to 24 (where this chain may be branched, optionally substituted, in particular substituted by hydroxyl, optionally unsaturated, in particular optionally a mono-, di- or tri-unsaturated hydrocarbon radical, preferably selected from the group consisting of pentenyl, heptenyl, nonenyl, undecenyl and tridecenyl and (CH2)o-CH3 with o=1 to 23, preferably 4 to 12, very particularly preferably o=6); R1 is H or a cation, preferably H, or a monovalent solubilizing cation, R2 is H or the o group CH3(CH2)mCH = CH ΐ-,

[0063] preferably H; m is 4 to 10; and the values ​​of men do not need to be the same in each occurrence.

[0064] Rhamnolipids can be produced by bacterial fermentation. This is inherently advantageous, as the products of bacterial fermentation can generally be derived from renewable raw materials and are likely to be biodegradable after use. Another advantage of surfactants of formula (I) is that they can be produced as a byproduct of enzyme manufacturing. Petition 870250084445, dated 09 / 19 / 2025, p. 29 / 73 15 / 46

[0065] Rhamnolipids can be produced by bacteria of the genus Pseudomonas. Bacterial fermentation typically uses a sugar or glycerol or an alkane or mixtures thereof as substrates.

[0066] Any sample of rhamnolipid will generally contain a variety of individual compounds within the general formula (I). The proportions of individual compounds are governed by the species of microorganisms, the specific strain employed for fermentation, the substrate materials provided for fermentation, and other fermentation conditions.

[0067] Bacterial fermentation generally produces compounds in which Ri is hydrogen or a solubilizing cation. Such compounds can undergo conversion between salt and acid forms in aqueous solution, depending on the pH of the solution. Common solubilizing cations are alkali metals, ammonium, and alkanolamines.

[0068] The term di-rhamnolipid in connection with the present invention is understood to mean compounds of general formula (I) or salts thereof wherein 2. The term mono-rhamnolipid in connection with the present invention means compounds of general formula (I) or salts thereof wherein a = 1.

[0069] Non-limiting examples of glucoselipid compounds with formula (II).

[0070] where R1 is H or a cation; p is 1 to 4; eq is 4 to 10, preferably 6. Petition 870250084445, dated 09 / 19 / 2025, page 30 / 73 16 / 46

[0071] Glycolipids can be produced by the bacterium Alcaligenes Sp.MMI. Glycolipids are recovered from the fermentation broth by solvent extraction using ethyl ether or a mixture of dichloromethane:methanol or chloroform:methanol.

[0072] Non-limiting examples of sophoroselipids include compounds with formula (III)

[0073] where R3 and R4 are individually H or an acetyl group; R5 is a saturated or unsaturated hydrocarbon group, hydroxylated or non-hydroxylated, with 1 to 9 carbon atoms, preferably a methyl group; R6 is a saturated or unsaturated hydrocarbon group, hydroxylated or non-hydroxylated, with 1 to 19 carbon atoms; provided that the total number of carbon atoms in groups R5 and R6 does not exceed 20 and is preferably from 14 to 18.

[0074] The sophorolipid can be incorporated as the open-chain free acid form, where R7 is H and R8 is OH, or in its lactone form, where a lactone ring is formed between R7 and R8 as shown by formula (IV). Petition 870250084445, dated 09 / 19 / 2025, page 31 / 73 17 / 46

[0075] where R3, R4 and R6 are as defined above; provided that at least one of R3 and R4 is an acetyl group.

[0076] Sophorolipids can be produced by yeast cells, for example Torulopsis apicola and Torulopsis bombicola. The fermentation process typically uses sugars and alkanes as substrates. The resulting product is a mixture of various open-chain sophorolipids and sophorolipid lactones, which can be used as a mixture, or the required form can be isolated. When the glycolipid biosurfactant comprises sophorolipids, the weight ratio of sophorolipids to additional surfactant is preferably in the range of 4:1 to 3:2 and is most preferably 4:1.

[0077] Non-limiting examples of trehaloselipids include compounds with the general formula (V). COOH Petition 870250084445, dated 09 / 19 / 2025, p. 32 / 73 18 / 46

[0078] where R9, R1° and R11 are individually a saturated or unsaturated, hydroxylated or non-hydroxylated hydrocarbon of 5 to 13 carbon atoms.

[0079] Trehaloselipids can be produced by bacterial fermentation using the marine bacterium Arthrobacter sp. Ek 1 or the freshwater bacterium Rhodococcus erythropolis.

[0080] Non-limiting examples of cellobioselipids may include compounds with the general formula (VI). CH3

[0081] where R1 is H or a cation; R12 is a saturated or unsaturated, hydroxylated or non-hydroxylated hydrocarbon with 9 to 15 carbon atoms, preferably 13 carbon atoms; R13 is H or an acetyl group; R14 is a saturated or unsaturated, hydroxylated or non-hydroxylated hydrocarbon with 4 to 16 carbon atoms.

[0082] Cellobioselipids can be produced by fungal cells of the genus Ustilago. When the glycolipid biosurfactant comprises cellobioselipids, the weight ratio of cellobioselipids to additional surfactant is preferably in the range of 4:1 to 2:3. Petition 870250084445, dated 09 / 19 / 2025, p. 33 / 73 19 / 46

[0083] The biosurfactant (first surfactant) may be present in an amount ranging from about 0.001% by weight to about 13.0% by weight, based on the total weight of the viscosity control composition, including all amounts and subranges in between. In some embodiments, the biosurfactant (first surfactant) may be present in an amount ranging from about 0.1% by weight to about 4.0% by weight, based on the total weight of the viscosity control composition, including all amounts and subranges in between. In some embodiments, the biosurfactant (first surfactant) may be present in an amount ranging from about 0.1% by weight to about 3.0% by weight, based on the total weight of the viscosity control composition, including all amounts and subranges in between.In some embodiments, the biosurfactant (first surfactant) may be present in an amount ranging from about 0.5% by weight to about 3.0% by weight, based on the total weight of the viscosity control composition, including all amounts and subranges in between. In some embodiments, the biosurfactant (first surfactant) may be present in an amount ranging from about 0.6% by weight to about 2.5% by weight, based on the total weight of the viscosity control composition, including all amounts and subranges in between. In some embodiments, the biosurfactant (first surfactant) may be present in an amount ranging from about 0.7% by weight to about 2.0% by weight, based on the total weight of the viscosity control composition, including all amounts and subranges in between.In some embodiments, the biosurfactant (first surfactant) may be present in an amount ranging from about 0.8% by weight to about 1.5% by weight, based on the total weight of the viscosity control composition, including all amounts and subranges in between. In some embodiments, the biosurfactant (first surfactant) may be present. Petition 870250084445, dated 09 / 19 / 2025, p. 34 / 73 20 / 46 in an amount ranging from about 0.9% by weight to about 1.2% by weight, based on the total weight of the viscosity control composition, including all amounts and subranges in between. In some embodiments, the biosurfactant (first surfactant) may be present in an amount of about 1.0% by weight, based on the total weight of the viscosity control composition.

[0084] The second surfactant in the surfactant mixture may comprise an anionic surfactant. The anionic surfactant(s) may be selected from non-sulfate-based anionic surfactants, such as sulfonated fatty acid monoglycerides, isethionates, sarcosinates, taurate, or a combination of two or more of these. Although one or more anionic surfactants are typically chosen from non-sulfate-based anionic surfactants, the oral hygiene composition may, in some embodiments, include sulfate-based anionic surfactants selected from ammonium lauryl sulfate, ammonium lauryl ether sulfate, sodium dodecyl sulfate, sodium cocosulfate, ammonium cocosulfate, and a combination of two or more of these.For example, in some formulations, the surfactant system includes an anionic sulfate-based surfactant, where the oral hygiene composition is substantially free or free of sodium lauryl sulfate and / or sodium lauryl ether sulfate.

[0085] Non-limiting examples of suitable anionic surfactants that may be used are alkylbenzene sulfonates, alkyl ether sulfates, olefin sulfonates, alkyl sulfonates, secondary alkyl sulfonates, fatty acid ester sulfonates, dialkyl sulfosuccinates and alkyl orthoxylene sulfonates. Specific examples of alkylbenzene sulfonates include alkali metal, ammonium or alkanolamine salts of alkylbenzene sulfonates with 10 to 18 carbon atoms in the alkyl group. Petition 870250084445, dated 09 / 19 / 2025, page 35 / 73 21 / 46

[0086] Suitable alkyl and alkyl ether sulfates include those having from 10 to 24 carbon atoms in the alkyl group, alkyl ether sulfates have from 1 to 5 ethylene oxide groups.

[0087] Suitable olefin sulfonates are those prepared by sulfonation of C10-C24 alpha-olefins and subsequent neutralization and hydrolysis of the sulfonation reaction product.

[0088] Specific examples of alkyl sulfates, or salts of sulfated fatty alcohols, include those with mixed alkyl chain length, in which the ratio of C12 alkyl chains to C18 alkyl chains is in the range of 9:4 to 1:6. A suitable material can be obtained from a mixture of synthetic lauryl and oleyl alcohols with appropriate properties.

[0089] Specific examples of fatty acid ester sulfonates include those of general formula 2 R --CH--COORS03Mem where R1 is derived from tallow, palm oil or coconut oil and R2 is a short-chain alkyl group, such as butyl.

[0090] Specific examples of dialkyl sulfosuccinates include those in which both alkyl substituents contain at least 4 carbon atoms and together contain 12 to 20 carbon atoms in total, such as C8 dialkyl sulfosuccinate.

[0091] Specific examples of alkyl orthoxylene sulfonates include those in which the alkyl group contains from 12 to 24 carbon atoms.

[0092] Other anionic surfactants that may be used include alkali metal soaps of a fatty acid, preferably one containing 12 to 18 carbon atoms. Such typical acids are acid Petition 870250084445, dated 09 / 19 / 2025, p. 36 / 73 22 / 46 oleic acid, ricinoleic acid, and fatty acids derived from castor oil, rapeseed oil, peanut oil, coconut oil, palm kernel oil, or mixtures thereof. Sodium or potassium soaps containing these acids may be used. In addition to acting as surfactants, soaps can also act as detergents or fabric softeners.

[0093] Dialkyl sulfosuccinates are of particular interest as anionic lamellar-phase surfactants for use in the present invention.

[0094] Suitable anionic surfactants are preferably C8-C18-alkylbenzenesulfonates, in particular having about 12 C atoms in the alkyl portion, C8-C20-alkanesulfonates, C8-C18-monoalkyl sulfates (fatty alcohol sulfates), C8-C18-alkyl polyglycol ether sulfates with 2 to 6 ethylene oxide (EO) units in the ether portion and C8-C18 mono- and disulfosuccinic alkyl esters. In addition, C8-C18-α-olefin sulfonates, C8-C18-sulfonated fatty acids, in particular dodecylbenzene sulfonate, C8-C22-carbonosaureamide tersulfate, C8-C18-alkyl polyglycol ether carboxylate, C8-C18-N-acyltaurate, N-acylaminosaurid derivatives such as N-acyl aspartates or N-acyl glutamates, C8-C18-N-sarcosinates and C8-C18-alkyl thionate or mixtures thereof.

[0095] In a non-limiting embodiment, the anionic surfactant is an amine-containing compound. In a non-limiting embodiment, the anionic surfactant is a C8-C18-N-sarcosinate-containing compound. In some embodiments, the anionic surfactant is sodium lauroyl sarcosinate. In some embodiments, the anionic surfactant comprises an amino acid-based anionic surfactant selected from acyl glutamates and glycinates.

[0096] Anionic surfactants are preferably used as sodium salts, but they can also be present as other alkali or alkaline earth metal salts, for example, magnesium salts, and in the form of ammonium or mono-, di-, tri- or tetraalkylammonium salts, in the case of Petition 870250084445, dated 09 / 19 / 2025, page 37 / 73 23 / 46 sulfonates also in the form of their corresponding acid, for example, dodecylbenzenesulfonic acid.

[0097] Examples of such surfactants are sodium cocoalkyl sulfate, sodium sec-alkanesulfonate with about 15 carbon atoms and sodium dioctylsulfosuccinate. Sodium fatty alkyl sulfates and fatty alkyl sulfates + 2EO ether with 12 to 14 C atoms have proven to be particularly suitable.

[0098] C8-C18 alcohol polyglycol ethers, i.e., ethoxylated and / or propoxylated alcohols with 8 to 18 C atoms in the alkyl portion and 2 to 15 ethylene oxide (EO) and / or propylene oxide (PO) units, are notable non-ionic surfactants. C18 carboxylic acid polyglycol esters with 2 to 15 EO, for example, tallow fatty acid esters + 6-EO, ethoxylated fatty acid amides with 12 to 18 C atoms in the fatty acid portion and 2 to 8 EO, long-chain amine oxides with 14 to 20 C atoms, and long-chain alkyl polyglycosides, to mention, with 8 to 14 carbon atoms in the alkyl portion and 1 to 3 glycosidic units. Examples of such surfactants are oleyl-cetyl-alcohol with 5 EO, nonylphenol with 10 EO, lauric acid diethanolamide, kokosalkyldimethylamine oxide, and kokosalkylpolyglucoside with an average of 1.4 glucose units.Particular preference is given to the use of polyglycol ethers of fatty alcohols having in particular 2 to 8 EO, for example C12-14-fatty alcohol + 4-EO ether, amine oxides and C8-10-alkyl polyglycosides with 1 to 2 glycosidic units.

[0099] The anionic (e.g., second surfactant) may be present in an amount ranging from about 0.1% by weight to about 13.0% by weight, based on the total weight of the viscosity control composition, including all amounts and subranges in between. In some embodiments, the anionic (second surfactant) may be present in an amount ranging from about 0.3% by weight to about 6.0%. Petition 870250084445, dated 09 / 19 / 2025, p. 38 / 73 24 / 46 by weight, based on the total weight of the viscosity control composition, including all quantities and subranges thereafter. In some embodiments, the anionic (second surfactant) may be present in an amount ranging from about 0.4% by weight to about 5.0% by weight, based on the total weight of the viscosity control composition, including all quantities and subranges thereafter. In some embodiments, the anionic (second surfactant) may be present in an amount ranging from about 0.5% by weight to about 3.5% by weight, based on the total weight of the viscosity control composition, including all quantities and subranges thereafter. In some embodiments, the anionic (second surfactant) may be present in an amount ranging from about 0.7% by weight to about 3.0% by weight, based on the total weight of the viscosity control composition, including all quantities and subranges thereafter.In some embodiments, the anionic (second surfactant) may be present in an amount ranging from about 0.9% by weight to about 2.5% by weight, based on the total weight of the viscosity control composition, including all amounts and subranges in between. In some embodiments, the anionic (second surfactant) may be present in an amount ranging from about 1.1% by weight to about 2.0% by weight, based on the total weight of the viscosity control composition, including all amounts and subranges in between. In some embodiments, the anionic (e.g., second surfactant) may be present in an amount ranging from about 1.3% by weight to about 1.7% by weight, based on the total weight of the viscosity control composition, including all amounts and subranges in between.In some formulations, the anionic (secondary surfactant) may be present in an amount of approximately 1.5% by weight, based on the total weight of the viscosity control composition. Petition 870250084445, dated 09 / 19 / 2025, p. 39 / 73 25 / 46

[0100] The third surfactant in the surfactant mixture may comprise an amphoteric compound, a zwitterionic compound and / or combinations thereof. Amphoteric or zwitterionic surfactants suitable for use in the composition described herein include those known for use in hair care or other personal hygiene cleaning.

[0101] Amphoteric surfactants suitable for use in the composition are well known in the art and include those surfactants broadly described as derivatives of secondary and tertiary aliphatic amines, in which the aliphatic radical may be linear or branched chain and in which one of the aliphatic substituents contains from about 8 to about 18 carbon atoms and one contains an anionic group, such as carboxyl, sulfonate, sulfate, phosphate or phosphonate. Suitable examples of such amphoteric surfactants include, but are not limited to, sodium cocaminopropionate, sodium cocaminodipropionate, sodium cocoamphoacetate, cocoampho- sodium hydroxypropylsulfonate, sodium cocoamphopropionate, sodium cornamphopropionate, sodium lauraminopropionate, sodium lauroamphoacetate, sodium lauroampho-hydroxypropylsulfonate, sodium lauroamphopropionate, sodium cornamphopropionate, sodium lauriminodipropionate, ammonium cocaminopropionate, ammonium cocaminodipropionate, ammonium cocoamphoacetate, ammonium cocoampho-hydroxypropylsulfonate, ammonium cocoamphopropionate, ammonium cornamphopropionate, ammonium lauraminopropionate, ammonium lauroampho-hydroxypropylsulfonate, ammonium lauroamphopropionate, ammonium cornamphopropionate, ammonium lauriminodipropionate, triethanol cocaminopropionate, triethanol cocaminodipropionate, triethanol cocoamphoacetate riethanol, triethanol cocoamphohydroxypropylsulfonate, triethanol cocoamphopropionate, triethanol cornamphopropionate, triethanol lauraminopropionate, triethanol lauroamphoacetate, triethanol lauroamphohydroxypropylsulfonate,triethanol lauroamphopropionate, Petition 870250084445, dated 09 / 19 / 2025, page 40 / 73 26 / 46 triethanolamphopropionate, triethanol lauriminodipropionate, cocoamphodipropionic acid, disodium caproamphodiacetate, disodium caproamphoadipropionate, disodium capryloamphodiacetate, disodium capryloamphodipriopionate, disodium cocoamphocarboxyethylhydroxypropylsulfonate, disodium cocoamphodiacetate, disodium cocoamphodipropionate, disodium dicarboxyethylcocopropylenediamine, disodium laureth-5 carboxyamphodiacetate, disodium lauriminodipropionate, disodium lauroamphodiacetate, disodium lauroamphodipropionate, disodium oleoamphodipropionate, disodium PPG-2-isodecetyl-7 carboxyamphodiacetate, lauraminopropionic acid, lauroamphodipropionic acid, lauryl aminopropylglycine, lauryl diethylenediaminoglycine, and combinations thereof.

[0102] In one embodiment, the amphoteric surfactant is a surfactant with the following structure: wherein R1 is a monovalent substituent bonded to C selected from the group consisting of substituted alkyl systems comprising from 9 to 15 carbon atoms, unsubstituted alkyl systems comprising from 1 to 15 carbon atoms, linear alkyl systems comprising from 9 to 15 carbon atoms, branched alkyl systems comprising from 9 to 15 carbon atoms, and unsaturated alkyl systems comprising from 9 to 15 carbon atoms; R2, R3, and R4 are each independently selected from the group consisting of straight divalent alkyl systems bonded to C comprising from 1 to 3 carbon atoms, and branched divalent alkyl systems bonded to C comprising from 1 to 3 carbon atoms. Petition 870250084445, dated 09 / 19 / 2025, page 41 / 73 27 / 46 carbon atoms; and M+ is a monovalent counter-ion selected from the group consisting of sodium, ammonium, and protonated triethanolamine.

[0103] Specific examples of suitable surfactants include sodium cocoamphoacetate, sodium cocoamphodiacetate, sodium lauroamphoacetate, sodium lauroamphodiacetate, ammonium lauroamphoacetate, ammonium cocoamphoacetate, triethanolamine lauroamphoacetate and triethanolamine cocoamphoacetate.

[0104] Suitable zwitterionic surfactants for use in the composition are well known in the art and include those surfactants broadly described as derived from aliphatic compounds of quaternary ammonium, phosphonium and sulfonium, in which the aliphatic radicals may be linear or branched chain, and in which one of the aliphatic substituents contains from about 8 to about 18 carbon atoms and one contains an anionic group, such as carboxyl, sulfonate, sulfate, phosphate or phosphonate.Suitable zwitterionic surfactants include, but are not limited to, cocamidoethyl betaine, cocamidopropylamine oxide, cocamidopropyl betaine, hydrolyzed cocamidopropyl dimethylaminohydroxypropyl collagen, hydrolyzed cocamidopropyldimonium hydroxypropyl collagen, cocamidopropyl hydroxysultain, cocobetaineamidoamphopropionate, coco-betaine, coco-hydroxysultain, coco / oleamidopropyl betaine, coco-sultain, lauramidopropyl betaine, lauryl betaine, lauryl hydroxysultain, lauryl sultaine, and combinations thereof.

[0105] In some embodiments, the surfactant mixture comprises a compound containing amphoacetate (for example, a second or third surfactant). In some embodiments, the surfactant mixture comprises a lauroamphoacetate compound. In some embodiments, the surfactant mixture comprises (for example, a third surfactant) sodium lauroamphoacetate.

[0106] Zwitterionic / amphoteric surfactant (e.g., third surfactant) may be present in an amount ranging from about Petition 870250084445, dated 09 / 19 / 2025, p. 42 / 73 28 / 46 1.0% by weight to about 24.0% by weight, based on the total weight of the viscosity control composition, including all quantities and subranges in between. In some embodiments, the zwitterionic / amphoteric surfactant (e.g., third surfactant) may be present in an amount ranging from about 2.0% by weight to about 14.0% by weight, based on the total weight of the viscosity control composition, including all quantities and subranges in between. In some embodiments, the zwitterionic / amphoteric surfactant (e.g., third surfactant) may be present in an amount ranging from about 3.0% by weight to about 12.0% by weight, based on the total weight of the viscosity control composition, including all quantities and subranges in between.In some embodiments, the zwitterionic / amphoteric surfactant (e.g., third surfactant) may be present in an amount ranging from about 4.0% by weight to about 11.0% by weight, based on the total weight of the viscosity control composition, including all amounts and subranges in between. In some embodiments, the zwitterionic / amphoteric surfactant (e.g., third surfactant) may be present in an amount ranging from about 5.0% by weight to about 10.0% by weight, based on the total weight of the viscosity control composition, including all amounts and subranges in between. In some embodiments, the zwitterionic / amphoteric surfactant (e.g., third surfactant) may be present in an amount ranging from about 6.0% by weight to about 9.0% by weight, based on the total weight of the viscosity control composition, including all amounts and subranges in between.In some embodiments, the zwitterionic / amphoteric surfactant (e.g., third surfactant) may be present in an amount ranging from about 6.5% by weight to about 8.0% by weight, based on the total weight of the viscosity control composition, including all amounts. Petition 870250084445, dated 09 / 19 / 2025, p. 43 / 73 29 / 46 subranges between them. In some embodiments, the zwitterionic / amphoteric surfactant (e.g., third surfactant) may be present in an amount ranging from about 7.0% by weight to about 8.0% by weight, based on the total weight of the viscosity control composition, including all amounts and subranges between them. In some embodiments, the zwitterionic / amphoteric surfactant (e.g., third surfactant) may be present in an amount of about 7.5% by weight, based on the total weight of the viscosity control composition.

[0107] The surfactant mixture may be present in an amount ranging from about 2% by weight to about 25% by weight, based on the total weight of the viscosity control composition, including all weight percent and subranges in between. In some embodiments, the surfactant mixture may be present in an amount ranging from about 3% by weight to about 18% by weight – based on the total weight of the viscosity control composition – including all weight percent and subranges in between. In some embodiments, the surfactant mixture may be present in an amount ranging from about 4% by weight to about 17% by weight – based on the total weight of the viscosity control composition – including all weight percent and subranges in between.In some embodiments, the surfactant mixture may be present in an amount ranging from about 5% by weight to about 16% by weight – based on the total weight of the viscosity control composition – including all weight percentages and subranges in between. In some embodiments, the surfactant mixture may be present in an amount ranging from about 6% by weight to about 15% by weight – based on the total weight of the viscosity control composition, including all weight percentages and subranges in between. In some embodiments, the surfactant mixture may be present in a... Petition 870250084445, dated 09 / 19 / 2025, p. 44 / 73 30 / 46 quantity ranging from about 7% by weight to about 14% by weight based on the total weight of the viscosity control composition - including all weight percentages and subranges in between. In some embodiments, the surfactant mixture may be present in an amount ranging from about 8% by weight to about 13% by weight based on the total weight of the viscosity control composition - including all weight percentages and subranges in between. In some embodiments, the surfactant mixture may be present in an amount ranging from about 8% by weight to about 12% by weight - based on the total weight of the viscosity control composition - including all weight percentages and subranges in between. In some embodiments, the surfactant mixture may be present in an amount ranging from about 9% by weight to about 11% by weight - based on the total weight of the viscosity control composition - including all weight percentages and subranges in between.In some applications, the surfactant mixture may be present in an amount of approximately 10% by weight based on the total weight of the viscosity control.

[0108] The anionic surfactant (e.g., second surfactant) and the biosurfactant (e.g., first surfactant) may be present in a weight ratio ranging from about 1:20 to about 20:1 including all sub-ranges of the ratio between them. In some embodiments, the anionic surfactant (e.g., second surfactant) and the biosurfactant (e.g., first surfactant) may be present in a weight ratio ranging from about 0.7:1 to about 2.0:1 including all sub-ranges of the ratio between them. In some embodiments, the anionic surfactant (e.g., second surfactant) and the biosurfactant (e.g., first surfactant) may be present in a weight ratio ranging from about 0.8:1 to about 1.9:1 including all sub-ranges of the ratio between them. In some Petition 870250084445, dated 09 / 19 / 2025, p. 45 / 73 In some embodiments, the anionic surfactant (e.g., second surfactant) and the biosurfactant (e.g., first surfactant) may be present in a weight ratio ranging from about 1.0:1 to about 1.8:1 including all sub-ranges of the ratio between them. In some embodiments, the anionic surfactant (e.g., second surfactant) and the biosurfactant (e.g., first surfactant) may be present in a weight ratio ranging from about 1.2:1 to about 1.7:1 including all sub-ranges of the ratio between them. In some embodiments, the anionic surfactant (e.g., second surfactant) and the biosurfactant (e.g., first surfactant) may be present in a weight ratio ranging from about 1.4:1 to about 1.6:1 including all sub-ranges of the ratio between them.In some embodiments, the anionic surfactant (e.g., second surfactant) and the biosurfactant (e.g., first surfactant) may be present in a weight ratio of approximately 1.5:1.

[0109] Amphoteric / zwitterionic surfactant (e.g., third surfactant) and biosurfactant (e.g., first surfactant) may be present in a weight ratio ranging from about 1:10 to about 10:1 – including all intermediate ratios and subranges. In some embodiments, amphoteric / zwitterionic surfactant (e.g., third surfactant) and biosurfactant (e.g., first surfactant) may be present in a weight ratio ranging from about 5.5:1 to about 9.5:1 – including all ratios and subranges in between. In some forms, amphoteric / zwitterionic surfactant, for example (third surfactant), and biosurfactant (e.g., first surfactant) may be present in a weight ratio ranging from about 6:1 to about 9:1 - including all ratios and subranges in between.In some forms, amphoteric / zwitterionic surfactant (e.g., third surfactant) and biosurfactant (e.g., first surfactant). Petition 870250084445, dated 09 / 19 / 2025, p. 46 / 73 32 / 46 surfactant) may be present in a weight ratio ranging from about 6.5:1 to about 8.5:1 – including all ratios and subranges in between. In some embodiments, amphoteric / zwitterionic surfactant (e.g., third surfactant) and biosurfactant (e.g., first surfactant) may be present in a weight ratio ranging from about 7:1 to about 8:1 – including all ratios and subranges in between. In some embodiments, amphoteric / zwitterionic surfactant (e.g., third surfactant) and biosurfactant (e.g., first surfactant) may be present in a weight ratio of about 7.5:1.

[0110] Amphoteric / zwitterionic surfactant (e.g., third surfactant) and anionic surfactant (e.g., second surfactant) may be present in a weight ratio ranging from about 1:13 to about 13:1 – including all ratios and subranges in between. In some embodiments, amphoteric / zwitterionic surfactant (e.g., third surfactant) and anionic surfactant (e.g., second surfactant) may be present in a weight ratio ranging from about 3:1 to about 7:1 – including all ratios and subranges in between. In some embodiments, amphoteric / zwitterionic surfactant (e.g., third surfactant) and anionic surfactant (e.g., second surfactant) may be present in a weight ratio ranging from about 3.5:1 to about 6.5:1 - including all ratios and subranges in between.In some embodiments, amphoteric / zwitterionic surfactant (e.g., third surfactant) and anionic surfactant (e.g., second surfactant) may be present in a weight ratio ranging from about 4:1 to about 6:1 – including all ratios and subranges in between. In some embodiments, amphoteric / zwitterionic surfactant (e.g., third surfactant) and anionic surfactant (e.g., second surfactant) may be... Petition 870250084445, dated 09 / 19 / 2025, p. 47 / 73 33 / 46 present in a weight ratio ranging from about 4.5:1 to about 5.5:1 – including all ratios and subranges in between. In some embodiments, amphoteric / zwitterionic surfactant (e.g., third surfactant) and anionic surfactant (e.g., second surfactant) may be present in a weight ratio of about 5:1.

[0111] The viscosity control composition may comprise a thickening agent. The thickening agent may be selected from one or more polysaccharides. In some embodiments, the polysaccharide may comprise one or more of the following: xanthan gum, tragacanth gum, carrageenan gum (also simply called “carrageenan”), alginates, agar-agar, gum arabic, guar gum, gellan gum, pectin, cellulose, welan, dituan gum, locust bean gum, locust bean seed extract, dammar gum, kauri gum, fir gum, fenugreek gum, anima gum (western or eastern) or a combination of two or more thereof. In some embodiments, the viscosity control composition has one or more thickening agents consisting of polysaccharide(s).

[0112] In other embodiments, the viscosity control composition has a reduced amount of, is essentially free of, or free of thickening agents selected from acrylates, acrylamides, colloidal silicates, or a combination of all of the foregoing. For example, the viscosity control composition may contain acrylates, acrylamides, colloidal silicates, individually, in an amount of about 3% by weight or less, about 2% by weight or less, about 1% by weight or less, about 0.5% by weight or less, about 0.1% by weight or less, about 0.05% by weight or less, or about 0.01% by weight or less, based on the total weight of the viscosity control composition. In at least one embodiment, the viscosity control composition is essentially free of or free of acrylates, acrylamides, and / or colloidal silicates. Petition 870250084445, dated 09 / 19 / 2025, page 48 / 73 34 / 46

[0113] In a preferred embodiment, the thickening agent is carrageenan. It has been surprisingly discovered that the use of a carrageenan thickening agent in combination with the surfactant mixture of the present invention results in an unexpected synergy, resulting in an effective tool for increasing viscosity. Specifically, the addition of carrageenan to the biosurfactant, anionic surfactant, and zwitterionic / amphoteric surfactant mixture provides a surprising increase in the viscosity of the overall mixture – compared to other thickening agents (e.g., carboxymethylcellulose).

[0114] Specifically, the thickening agent – ​​specifically, carrageenan – can be added to the viscosity control composition in a nearly linear manner to build up the overall viscosity in a non-linear way (i.e., exceeding linear increases in viscosity based on linear additions of carrageenan to the overall viscosity control composition). Thus, the newly discovered synergy of mixing surfactants with carrageenan provides an efficient method for increasing viscosity without requiring large amounts of thickening agent.

[0115] The thickening agent may be present in an amount ranging from about 0.05% by weight to about 10% by weight – based on the total weight of the viscosity control composition – including all weight percentages and subranges in between. In some embodiments, the thickening agent may be present in an amount ranging from about 0.1% by weight to about 5.0% by weight – based on the total weight of the viscosity control composition – including all weight percentages and subranges in between. In some embodiments, the thickening agent may be present in an amount ranging from about 0.2% by weight to about 4.0% by weight – based on the total weight of the viscosity control composition – including all weight percentages and subranges in between. In some embodiments, the thickening agent may be present Petition 870250084445, dated 09 / 19 / 2025, page 49 / 73 35 / 46 in an amount ranging from about 0.2% by weight to about 3.0% by weight – based on the total weight of the viscosity control composition – including all weight percentages and subranges in between. In some embodiments, the thickening agent may be present in an amount ranging from about 0.2% by weight to about 2.0% by weight – based on the total weight of the viscosity control composition – including all weight percentages and subranges in between.

[0116] In some embodiments, the thickening agent may be present in an amount of approximately 0.1% by weight – based on the total weight of the viscosity control composition. In some embodiments, the thickening agent may be present in an amount of approximately 0.2% by weight – based on the total weight of the viscosity control composition. In some embodiments, the thickening agent may be present in an amount of approximately 0.3% by weight – based on the total weight of the viscosity control composition. In some embodiments, the thickening agent may be present in an amount of approximately 0.4% by weight – based on the total weight of the viscosity control composition. In some embodiments, the thickening agent may be present in an amount of approximately 0.5% by weight – based on the total weight of the viscosity control composition.In some embodiments, the thickening agent may be present in an amount of approximately 0.6% by weight – based on the total weight of the viscosity control composition. In some embodiments, the thickening agent may be present in an amount of approximately 0.7% by weight – based on the total weight of the viscosity control composition. In some embodiments, the thickening agent may be present in an amount of approximately 0.8% by weight – based on the total weight of the viscosity control composition. In some embodiments, the thickening agent may be present in an amount of approximately 0.9% by weight – based on weight. Petition 870250084445, dated 09 / 19 / 2025, pp. 50 / 73 36 / 46 total of the viscosity control composition. In some embodiments, the thickening agent may be present in an amount of approximately 1.0% by weight – based on the total weight of the viscosity control composition. In some embodiments, the thickening agent may be present in an amount of approximately 1.1% by weight – based on the total weight of the viscosity control composition. In some embodiments, the thickening agent may be present in an amount of approximately 1.2% by weight – based on the total weight of the viscosity control composition. In some embodiments, the thickening agent may be present in an amount of approximately 1.3% by weight – based on the total weight of the viscosity control composition. In some embodiments, the thickening agent may be present in an amount of approximately 1.4% by weight – based on the total weight of the viscosity control composition.In some embodiments, the thickening agent may be present in an amount of approximately 1.5% by weight – based on the total weight of the viscosity control composition. In some embodiments, the thickening agent may be present in an amount of approximately 1.6% by weight – based on the total weight of the viscosity control composition. In some embodiments, the thickening agent may be present in an amount of approximately 1.7% by weight – based on the total weight of the viscosity control composition. In some embodiments, the thickening agent may be present in an amount of approximately 1.8% by weight – based on the total weight of the viscosity control composition. In some embodiments, the thickening agent may be present in an amount of approximately 1.9% by weight – based on the total weight of the viscosity control composition.In some embodiments, the thickening agent may be present in an amount of approximately 2.0% by weight – based on the total weight of the viscosity control composition. In some embodiments, the thickening agent may be... Petition 870250084445, dated 09 / 19 / 2025, pp. 51 / 73 37 / 46 present in an amount of approximately 2.1% by weight - based on the total weight of the viscosity control composition.

[0117] The viscosity control composition may comprise a liquid carrier. The liquid carrier may comprise one or more of the following: solvent, diluent, and combinations thereof. The liquid carrier may comprise one or more of the following: water, alcohols (e.g., ethanol, isopropanol, propanol, or mixtures thereof), and mixtures thereof. In at least one embodiment, the carrier comprises water.

[0118] In some embodiments, the carrier comprises or excludes a polyol selected from glycerin, ethylene glycol, propylene glycol, butylene glycol, hexylene glycol, diglycerin, diethylene glycol, dipropylene glycol, 1,2,6-hexanetriol, trimethylolpropane, ethylene glycol, propylene glycol, butylene glycol, pentylene glycol, hexylene glycol, diethylene glycol, triethylene glycol, tetraethylene glycol, pentaethylene glycol, dipropylene glycol, 2-butene-1,4-diol, 2-ethyl-1,3-hexanediol, 2-methyl-2,4-pentanediol, caprylyl glycol, 1,2-hexanediol, 1,2-pentanediol and 4-methyl-1,2-pentanediol;Glycol ethers, such as ethylene glycol monomethyl ether, ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, ethylene glycol monomethyl ether acetate, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, diethylene glycol mono-n-propyl ether, ethylene glycol mono-isopropyl ether, diethylene glycol mono-isopropyl ether, ethylene glycol mono-n-butyl ether, ethylene glycol mono-t-butyl ether, diethylene glycol mono-t-butyl ether, 1-methyl-1-methoxybutanol, propylene glycol monomethyl ether, propylene glycol monoethyl ether, propylene glycol mono-t-butyl ether, propylene glycol mono-n-propyl ether, propylene glycol monoisopropyl ether, monomethyl ether dipropylene glycol, dipropylene glycol monoethyl ether, dipropylene glycol mono-n-propyl ether, dipropylene glycol monoisopropyl ether, sorbitol, sorbitan, triacetin and a mixture of two or more of these. Petition 870250084445, dated 09 / 19 / 2025, pp. 52 / 73 38 / 46

[0119] The amount of carrier present in the personal hygiene formulation may vary, for example, from about 75 to about 98% by weight, based on the total weight of the viscosity control composition, including all weight percent and subranges in between. In some embodiments, the amount of carrier present in the personal hygiene formulation may vary, for example, from about 81 to about 93% by weight, based on the total weight of the viscosity control composition, including all weight percent and subranges in between. In some embodiments, the amount of carrier present in the personal hygiene formulation may vary, for example, from about 85 to about 91% by weight, based on the total weight of the viscosity control composition, including all weight percent and subranges in between.In some embodiments, the amount of carrier present in the personal hygiene formulation may vary, for example, from about 88 to about 90% by weight, based on the total weight of the viscosity control composition, including all weight percentages and subranges in between.

[0120] In some embodiments, the mixture of surfactant, thickening agent and liquid carrier make up approximately 100% by weight of the viscosity control composition.

[0121] In a preferred embodiment, the viscosity control composition may comprise a mixture of surfactants comprising a biosurfactant that includes rhamnolipid, an anionic surfactant that includes sodium lauroyl sarcosinate and a zwitterionic surfactant that includes sodium lauroamphoacetate, whereby the viscosity control composition further comprises a thickening agent that is a gum that includes carrageenan, as well as a liquid carrier.

[0122] In this embodiment, rhamnolipid may be present in an amount of approximately 1.0% by weight based on the total weight of the viscosity control composition; sodium lauroyl sarcosinate is Petition 870250084445, dated 09 / 19 / 2025, pp. 53 / 73 39 / 46 present in an amount of approximately 1.5% by weight based on the total weight of the viscosity control composition; sodium lauroamphoacetate is present in an amount of approximately 7.5% by weight based on the total weight of the viscosity control composition; carrageenan is present in an amount ranging from approximately 0.2% by weight to approximately 2.0% by weight based on the total weight of the viscosity control agent - whereby rhamnolipid, sodium lauroyl sarcosinate, sodium lauroamphoacetate, carrageenan and the liquid carrier total 100% by weight of the viscosity control composition.

[0123] The present invention further includes a personal hygiene composition comprising a viscosity control composition. The personal hygiene composition may be a cleaning product. Non-limiting examples of the personal hygiene composition may be liquid hand soap, facial cleanser, shower gel, shampoo, conditioner, liquid soap or skin cleanser.

[0124] In addition to the viscosity control composition, the personal hygiene composition may also comprise one or more personal hygiene ingredients.Other, but not limited, examples of such personal care ingredients include preservatives, antibacterial agents, perfumes or fragrances, colorants or dyes, conditioners, hair lighteners, moisturizers, emollients, pharmaceutical actives, vitamins or nutrients, sunscreens, deodorants, sensitizers, plant extracts, nutrients, astringents, cosmetic particles, absorbent particles, adhesive particles, hair fixatives, fibers, reactive agents, skin lighteners, skin tanners, anti-dandruff agents, perfumes, exfoliants, acids, bases, humectants, enzymes, suspending agents, pH modifiers, hair dyes, hair perms, pigment particles, anti-acne agents, antimicrobials, sunscreens, tanning agents, exfoliating particles, hair growth or restoration agents, insect repellents, lotions. Petition 870250084445, dated 09 / 19 / 2025, pp. 54 / 73 40 / 46 shaving cream, co-solvents or other additional solvents and other similar materials.

[0125] In some embodiments, the personal care ingredient may comprise at least one fragrance. The fragrance may contain one or more essential oils. At least one essential oil may be selected, without limitation, from the following essential oils: ambrette, angelica, anise, amyris, laurel, bergamot, basil, bois-de-rose, cade, cajiput, camphor, cananga, Java cassia, clary sage, curry, calamus, costus, carrot, cedarwood, cedar, cinnamon, Java citronella, clove, cypress, cyperiol, blue chamomile, Roman chamomile, davana, dill, elemi, eucalyptus, eucalyptus globules, frankincense, geranium, gingergrass, ginger lily, galangal, gurjam, grapefruit, jasmine, juniper, kapoor katcheri, lavender, lemon, lemongrass, lemon balm, lime, laurel, peppermint, lemongrass, litsea Cubeb, lemongrass, peppermint, shivalik mint, tangerine, marjoram, spearmint, myrtle, nar kachur, neroli, niaouli, orange, sweet orange, oreganobitter patchouli, petitgrain, peppermint, pine, palmarosa, chili pepper, rosewood, rose quince, rosemary, sandalwood, mint, sugandh mantri (Gandhi roots), spiked spikenard, tarragon, tangerine, tea tree, thyme, thuja wood, tomato (Zanthozylum), tagetues, vetiver, valerian, wintergreen, wormwood (Gaultheria fragrantissimus wall), ylang-ylang, zadoeria and any combination thereof.

[0126] In addition, or as an alternative to the aforementioned essential oil, the formulation may comprise at least one additional plant extract selected from wasabi, blackcurrant, poplar bark, Lonicera species and others. In some embodiments, the amount of perfume is in the range of about 0.1% by weight to about 5% by weight, based on the total weight of the personal care composition. Petition 870250084445, dated 09 / 19 / 2025, pp. 55 / 73 41 / 46

[0127] The personal care ingredient may further comprise at least one natural preservative, which may be one or more of an extract of anise, blackcurrant, cinnamon or cinnamon oil, geranium or geranium oil, ginger or ginger oil, Indian ginseng root, lavender, lemongrass, Magnolia anibio, maritime pine, Mentha piperita, olive leaf, oregano, peppermint, elderberry, rosemary, tea tree, thyme and grapefruit. In some embodiments, the amount of at least one preservative is in the range of about 0.1% by weight to about 5% by weight based on the total weight of the personal care composition.

[0128] The personal hygiene composition may also comprise a natural extract, for example, a plant extract from one or more genera of Lonicera, Populus, Salix and Wasabia or a combination thereof. It should be understood that the extract may be an extract from more than one plant selected from Lonicera, Populus, Salix and Wasabia and that each plant may be selected from the same genus or from a different genus. It should also be noted that the present invention also contemplates the personal hygiene composition comprising mixtures of extracts, prepared and formulated individually or prepared in a single container from a mixture of plant sources (plant parts).

[0129] Non-limiting examples of enzymes may include proteases, lipases, amylases, hydrolases and / or cellulases. To protect an enzyme contained in an agent according to the invention from damage such as inactivation, denaturation or decomposition, for example, by physical influences, oxidation or proteolytic cleavage, enzyme stabilizers may be added to the enzyme-containing agent.

[0130] Depending on the type of enzyme used, suitable enzyme stabilizers are, for example: benzamidine hydrochloride, borax, boric acids, boronic acids or their salts or esters, especially derivatives with aromatic groups, for example, phenylboronic acids. Petition 870250084445, dated 09 / 19 / 2025, pp. 56 / 73 42 / 46 substituted compounds or their salts or esters; peptide aldehydes, amino alcohols such as mono-, di-, triethanolamine- and -propanolamine and mixtures thereof, aliphatic carboxylic acids up to C12, such as succinic acid, other dicarboxylic acids or salts of said acids; amide alkoxylates of fatty acids with termination; lower aliphatic alcohols and especially polyols, for example, glycerol, ethylene glycol, propylene glycol or sorbitol; and reducing and antioxidant agents, such as sodium sulfite and reducing sugars. Other suitable stabilizers are known in the art.

[0131] Particularly suitable according to the invention are enzymes produced biotechnologically with the aid of non-genetically modified (non-GMO) organisms, stabilizers based on renewable raw materials and / or mineral substances, for example, boric acid and / or borax, reducing sugars, succinic acid or other dicarboxylic acids, polyamino compounds based on natural amino acids.

[0132] Surprisingly, in the enzyme-free embodiment, exceptional cleansing performance is found in relation to carbohydrates, which is quite comparable to enzyme-containing agents on the market, as exemplified in the exemplary embodiments. A particularly preferred embodiment of the invention is therefore that without cellulases or amylases, with the enzyme-free embodiment being much more preferred. This is particularly beneficial for consumers with allergies and / or sensitive skin. Enzyme-free embodiments with comparable cleansing power are disclosed here, for example, in the embodiments.

[0133] Non-limiting examples of antibacterial agents may include alcohols, aldehydes, antimicrobial acids or their salts, carboxylic esters, acid amides, phenols, phenol derivatives, diphenyl, diphenylalkanes, urea derivatives, oxygen, nitrogen acetals and formalins, benzamidines, isothiazoles and their derivatives are suitable according to the invention. Petition 870250084445, dated 09 / 19 / 2025, pp. 57 / 73 43 / 46 Derivatives such as isothiazolines and isothiazolinones, phthalimide derivatives, pyridine derivatives, antimicrobial surface-active compounds, guanidines, amphoteric antimicrobial compounds, quinolines, 1,2-dibromo-2,4-dicyanobutane, iodo-2-propynyl-butyl-carbamate, iodine, iodophors, and peroxides. Preferred antimicrobial agents are preferably selected from the group comprising ethanol, n-propanol, i-propanol, 1,3-butanediol, phenoxyethanol, 1,2-propylene glycol, glycerol, undecylenic acid, citric acid, lactic acid, benzoic acid, salicylic acid, thymol, 2-benzyl 4-chlorophenol, 2,2'-methylenebis(6-bromo-4-chlorophenol), 2,4,4'-trichloro-2'-hydroxydiphenyl ether, N-(4-chlorophenyl)-N-(3,4-dichlorophenyl)urea, N,N'-(1,10-decanodiyldi-1-pyridinyl-4-ylidene)bis(1-octanamine) dihydrochloride, N,N'-bis(4-chlorophenyl) -3,12-diimino-2,4,11,13-tetraazatetradecandiimidamide, antimicrobial quaternary surface-active compounds, guanidines.Preferred antimicrobial surface-active quaternary compounds contain an ammonium, sulfonium, phosphonium, iodonium, or arson group.

[0134] In addition, essential oils with antimicrobial action may be used, which at the same time impart aroma to the cleaning agent. However, particularly preferred antimicrobial agents are selected from the group comprising salicylic acid, quaternary surfactants, in particular benzalkonium chloride, peroxo compounds, in particular hydrogen peroxide, alkali metal hypochlorite and mixtures thereof.

[0135] The personal hygiene composition may be supplied in a container - a resealable bottle configured so that the personal hygiene composition is dispensed incrementally at the time of desired use - for example, during bathing.

[0136] The present invention also provides a method for manufacturing a personal hygiene product with viscosity control. The method comprises: mixing the viscosity control composition with the Petition 870250084445, dated 09 / 19 / 2025, pp. 58 / 73 44 / 46 personal hygiene ingredient to form the personal hygiene composition. Subsequently, the method comprises adding a predetermined volume of the personal hygiene composition to the container to form the personal hygiene product. EXAMPLES

[0137] The following experiments tested the impact on rheology based on the mixture of surfactants with various gums in the viscosity control composition. Experiment 1 - Comparison of Various Gums

[0138] The surfactant mixture included rhamnolipid, sodium lauroyl sarcosinate (“LS”), and sodium lauromanfoacetate (“LA”). The various gums included carrageenan, carboxymethylcellulose (“CMC”), and xanthan gum (“XG”). The formulation of each example is presented below in Table 1; each numerical value represents a weight percentage (% by weight).

[0139] An experiment was conducted to test the impact of reducing bad breath over time using the deodorant formulation of the present invention - the formulations are presented below in Table 1. Table 1 Comp. Ex. 1 Comp. Ex. 2 Comp. Ex. 3 Ex. 1 Rhamnolipid 1.0% by weight 1.0% by weight 1.0% by weight 1.0% by weight LS 1.5% by weight 1.5% by weight 1.5% by weight 1.5% by weight LA ​​7.5% by weight 7.5% by weight 7.5% by weight 7.5% by weight Carrageenan ^B ^B ^B 1.0% by weight CMC ^B 1.0% by weight ^B ^B XG ^B ^B 1.0% by weight ^B Water qsqsqsqs Total 100% by weight 100% by weight 100% by weight 100% by weight Viscosity 723 cP 937 cP 2278 cP 3317 cP

[0140] Comparative Example 1 (Ex. Comp. 1) omitted each of the carrageenan, CMC, and XG gums and exhibited a viscosity of 723 cP – which serves as a baseline control for the other viscosities of Comp. Ex. 2-3 and Ex. 1 for comparison. The formulation of Ex. Comp. 2 presents a Petition 870250084445, dated 09 / 19 / 2025, pp. 59 / 73 45 / 46 The minimal increase in viscosity compared to Ex. Comp. 1 results in a marginal viscosity buildup due to the presence of CMC. The formulation of Ex. Comp. 3 shows an increase in viscosity that was more than double compared to Ex. Comp. 1, but surprisingly, the formulation of Example 1 (Ex. 1) shows an unexpected increase in viscosity that is almost five times the viscosity of Ex. Comp. 1, resulting in a substantial increase in viscosity due to the carrageenan. Experiment 2 - Comparison of carrageenan loading levels Table 2 Ex. 1 Ex. 2 Ex. 3 Ex. 4 Ex. 5 Ex. 6 Rhamnolipid 1.0% by weight 1.0% by weight 1.0% by weight 1.0% by weight 1.0% by weight 1.0% by weight LS 1.5% by weight 1.5% by weight 1.5% by weight 1.5% by weight 1.5% by weight 1.5% by weight LA ​​7.5% by weight 7.5% by weight 7.5% by weight 7.5% by weight 7.5% by weight 7.5% by weight Carrageenan 1.0% by weight 0.2% by weight 0.5% by weight 0.8% by weight 1.5% by weight 2.0% by weight Water qsqsqsqsqsqs Total 100% by weight 100% by weight 100% by weight 100% by weight 100% by weight 100% by weight Viscosity 3317 cP 723 cP 1427 cP 2263 cP 6142 cP 12080 cP

[0141] As demonstrated in Table 2, the addition of carrageenan provides an effective tool for controlling the increase in viscosity of the surfactant formulation. Specifically, the same viscosity built up as Ex. Comp. 1 can be achieved using only 1 / 5 of the amount of gum when that gum is carrageenan. Furthermore, the data in Table 2 demonstrated that carrageenan confers a synergistic effect on increasing viscosity, as increasing the amount of carrageenan has a non-linear increase in the viscosity of the resulting surfactant formulation, thus providing an effective and efficient method of increasing viscosity without requiring large amounts of gum to achieve the desired viscosities. Petition 870250084445, dated 09 / 19 / 2025, pp. 60 / 73 46 / 46

[0142] Although the invention has been described in relation to specific examples including currently preferred ways of carrying out the invention, those skilled in the art will appreciate that there are numerous variations and permutations of the systems and techniques described above. It should be understood that other embodiments may be used and structural and functional modifications may be made without departing from the scope of the present invention. Thus, the spirit and scope of the invention should be interpreted broadly, as set forth in the appended claims. Petition 870250084445, dated 09 / 19 / 2025, pp. 61 / 73

Claims

1 / 3 CLAIMS 1. Viscosity control composition, characterized in that it comprises: a mixture of surfactants comprising: a biosurfactant; an anionic surfactant; a zwitterionic surfactant comprising sodium lauroamphoacetate; a gum comprising carrageenan; and a liquid carrier.

2. Viscosity control composition, according to claim 1, characterized in that the biosurfactant comprises rhamnolipid; and wherein the biosurfactant is present in an amount ranging from about 0.01% by weight to about 13% by weight based on the weight of the viscosity control composition.

3. Viscosity control composition, according to claim 1 or 2, characterized in that the anionic surfactant comprises an amine-containing compound; optionally in that the anionic surfactant comprises sodium lauroyl sarcosinate; and optionally in that the anionic surfactant is present in an amount ranging from about 0.1% by weight to about 13.0% by weight based on the weight of the viscosity control composition.

4. Viscosity control composition, according to any one of claims 1 to 3, characterized in that the zwitterionic surfactant is present in an amount ranging from about 1.0% by weight to about 24.0% by weight based on the weight of the viscosity control composition.

5. Viscosity control composition, according to any one of claims 1 to 4, characterized in that the gum is present in an amount ranging from about 0.1% by weight to about 5.0% by weight based on the weight of the viscosity control composition; optionally wherein the gum consists of carrageenan.

6. Viscosity control composition, according to any one of claims 1 to 5, characterized in that the anionic surfactant and the biosurfactant are present in a weight ratio ranging from about 0.6:1 to about 2:1; wherein the zwitterionic surfactant and the biosurfactant are present in a weight ratio ranging from about 5:1 to about 10:1; or wherein the gum and the biosurfactant are present in a weight ratio ranging from about 0.5:1 to about 2:

1.

7. Viscosity control composition, characterized in that it comprises: a mixture of surfactants comprising: a biosurfactant; an anionic surfactant; a zwitterionic surfactant; a gum comprising carrageenan; and a liquid carrier; wherein the anionic surfactant and the biosurfactant are present in a weight ratio ranging from about 0.6:1 to about 2:1; wherein the zwitterionic surfactant and the biosurfactant are present in a weight ratio ranging from about 5:1 to about 10:1; and wherein the gum and the biosurfactant are present in a weight ratio ranging from about 0.5:1 to about 2:

1.

8. Viscosity control composition, characterized in that it comprises: a rhamnolipid; sodium lauroyl sarcosinate; sodium lauroamphoacetate; carrageenan; and a liquid carrier.

9. Personal hygiene composition, characterized in that it comprises: a viscosity control composition according to any one of claims 1 to 8; and a personal hygiene ingredient; wherein the personal hygiene composition is a hygienic soap, shower gel, shampoo, conditioner, liquid soap or skin cleanser.

10. Method for manufacturing a viscosity-controlled personal care product, the method characterized in that it comprises: mixing a viscosity-control composition, according to Petition 870250084445, dated 09 / 19 / 2025, pp. 68 / 73 3 / 3, any one of claims 1 to 8, with a personal care ingredient to form a personal care composition; and adding a predetermined volume of the personal care composition to a container to form the personal care product. Petition 870250084445, dated 09 / 19 / 2025, pp. 69 / 73

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