Ketohexokinase (khk) arni compositions and methods of their use

CL202600445A1Pending Publication Date: 2026-07-03ALNYLAM PHARMACEUTICALS INC

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Patent Information

Application Number: CL202600445
Authority / Receiving Office: CL · CL
Patent Type: Applications
Current Assignee / Owner
Priority Date: 2022-02-18
Filing Date: 2026-02-13
Publication Date: 2026-07-03

Application Information

Patent Timeline

18 Feb 2022

Priority

13 Feb 2026

Application

CL202600445

03 Jul 2026

Publication

CL202600445A1

IPC: A61K47/02; A61K31/713; A61P3/06; A61P3/08; A61P13/12; C12N15/113

CPC: C12N15/1137; C12N2310/14; C12N2310/315; C12N2310/346; C12N2310/321; C12N2310/322; C12N2310/351; A61K31/713

Inventors: NOETZLI Leila; MCININCH James D.

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Abstract

The present invention relates to RNAi agents, for example, dsRNA agents, targeting the ketohexokinase (KHK) gene. The invention also relates to methods of using such RNAi agents to inhibit the expression of a KHK gene and to methods of treating or preventing a KHK-associated disorder in a subject.

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