Alpha-synuclein detection assay.

CL202600646A1Pending Publication Date: 2026-07-03THE UNIV COURT OF THE UNIV OF EDINBURGH
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Patent Information

Application Number
CL202600646
Authority / Receiving Office
CL · CL
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-09-04
Filing Date
2026-03-05
Publication Date
2026-07-03
Patent Text Reader

Abstract

A method is provided for detecting the presence of alpha-synuclein aggregation in a biological sample whereby a biological sample is mixed with a reaction sample comprising a bead population, a fluorophore adapted to bind to protein aggregates and to increase fluorescence when bound to protein aggregates, and alpha-synuclein or a fragment or variant thereof to form a reaction mixture, wherein a significant increase in the fluorescence of the reaction mixture during incubation is indicative of the presence of alpha-synuclein aggregates in the biological sample.
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