telomere-directed phosphatidyl-thio conjugates
CL202601349A1Pending Publication Date: 2026-07-10MAIA BIOTECHNOLOGY INC
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Patent Information
- Application Number
- CL202601349
- Authority / Receiving Office
- CL · CL
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-10-29
- Filing Date
- 2026-04-27
- Publication Date
- 2026-07-10
Abstract
This description describes telomere-targeting phosphatidyl-thio conjugates comprising nucleoside analogues 6-thio-2'-deoxyguanosine and 6-thioguanosine, which target telomeres in cancer cells, as well as pharmaceutical compositions thereof, and therapeutic methods for administering a therapeutically effective amount of the telomere-targeting phosphatidyl-thio conjugate compounds to treat cancers such as colorectal cancer, non-small cell lung cancer, and hepatocellular cancer.
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