Anti-pd-1 monoclonal antibody and methods for preparing it.

Abstract

This document describes a human anti-PD-1 monoclonal antibody and methods for its preparation. The human anti-PD-1 monoclonal antibody can bind to an extracellular region of a human PD-1 protein receptor and can seal the PD-1 protein at both the protein and cellular levels, blocking PD-1 protein binding and thus enhancing immunity. The monoclonal antibody can be administered alone, in combination with other drugs, or in any specific order to treat a patient in need.