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Application of isostearyl alcohol as absorption promoting agent through hair

An absorbent, pan-based technology, applied in hair care, cosmetic preparations, cosmetics, etc., can solve the problem of the preparation of tissue slices, the lack of direct research on hair absorption and sebum transfer of hair nourishing agents, difficulties, etc. question

Inactive Publication Date: 2008-02-13
SHISEIDO CO LTD
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

[0007] However, the above-mentioned method (1) is not a quantitative method but a qualitative method, and there is a disadvantage that preparation of tissue slices is labor-intensive.
In addition, in the above-mentioned method ②, the absorption of the drug is only studied from the aspect of transdermal absorption, and the absorption through the hair and the transferability of sebum, which are important as hair nourishing agents, have not been directly studied.
[0008] Therefore, it is very difficult to directly screen whether the drug reaches the point of action and whether it can fully exert the desired effect based on these previous technologies.

Method used

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  • Application of isostearyl alcohol as absorption promoting agent through hair
  • Application of isostearyl alcohol as absorption promoting agent through hair
  • Application of isostearyl alcohol as absorption promoting agent through hair

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Embodiment

[0098] The present invention will be specifically described below with reference to examples, but the present invention is not limited to these examples. Unless otherwise specified, the proportioning amount is the mass % of the compounding object.

[0099] This assay 1-1

[0100] 1. Evaluation of the accuracy of this assay 1-1

[0101] As a test sample, 0.5% panthenyl ethyl ether (90% ethanol preparation) was used. Micropig skin (Yucatan Micropig Skin Set: Charles River Corporation) was used as a skin model.

[0102] That is, as shown in FIG. 2, a micropig skin specimen 10 (maintaining stratum corneum 11, epidermis 12, and dermis 13) of 2 × 2 cm is prepared and fixed on the collagen gel to form a simulated body state. Apply 20 μl of the sample to be tested on the skin sample containing the pores 14 within a range of 1.5 cm in diameter (in the detection ring coated with silicon lubricating oil). Keeping this state, after standing at 37° C. for 16 hours, the skin sample 10 w...

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Abstract

The present invention provides application of a composition containing a skin absorbability substance wherein the skin absorbability substance absorption-improving component is iso-stearyl alcohol, and application of a composition for scalp and hair and product forms thereof.

Description

[0001] This case is a divisional application with the application number 200410033420.6, the application date is October 30, 2000, and the application name is "Skin Absorption Measurement Method of Detected Object". technical field [0002] The present invention relates to a screening method for ingredients acting on hair, a device for screening, and a composition containing ingredients confirmed to have trans-hair absorption promoting effects and sebum transfer promoting effects according to the screening methods. Background technique [0003] When developing a hair nourishing agent, its active ingredients certainly have an excellent hair nourishing effect, but what is important is that its active ingredients really have the permeability to reach the point of action. Whether it can really reach the point of action depends to a large extent on the properties of its active ingredients and the properties of the hair nourishing agent matrix. [0004] In addition, the absorption...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/34A61K8/44A61Q5/00
Inventor 武冈永里子高本隆一梁木利男
Owner SHISEIDO CO LTD
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