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Technology for producing constipation-relieving capsule

A technology for the treatment of constipation and production technology, applied in the direction of capsule delivery, medical preparations containing active ingredients, plant raw materials, etc., can solve problems such as poor drug efficacy, increased water content, and reduced content of anhydrous aloin, and achieve control of special structures , not easy to store time, not easy to agglomerate

Active Publication Date: 2010-05-19
FUZHOU CHENXING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] To sum up, the aloe products for laxative and laxative obtained by the existing production process mainly have the following problems: ① the content of anhydrous aloin is low, and the drug effect is poor; ② the stability of anhydrous aloin with special chemical structure cannot be ensured ; ③ anhydrous aloin is easily lost in the production process; ④ the content of anhydrous aloin in the product decreases with the prolongation of storage time, but the moisture gradually increases; ⑤ the product is easy to agglomerate

Method used

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  • Technology for producing constipation-relieving capsule
  • Technology for producing constipation-relieving capsule
  • Technology for producing constipation-relieving capsule

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Embodiment Construction

[0012] The chemical structure of anhydrous aloin is unstable, especially under high temperature and high humidity conditions, it is prone to oxidation, hydrolysis and other reactions. As shown in the following equation, it is the chemical equation for the hydrolysis reaction of anhydrous aloin under high temperature and high humidity conditions, and the chemical equation for the reduction of the anhydrous aloin nucleus under acidic conditions:

[0013]

[0014] Anhydrous aloin belongs to the derivatives of anthracenols, and anthracenols are reduced under acidic conditions to produce anthracenols and their tautomers anthrone.

[0015] Therefore, to prevent the loss of anhydrous aloin in the capsule-Shumi Capsule (hereinafter referred to as Shumi Capsule) for the treatment of constipation; the production process of a kind of Shumi Capsule provided by the present invention comprises the following steps:

[0016] ①Material selection: The raw material must be Aloe Vera from Soma...

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Abstract

The invention is concerned with the manufacturing technique of capsule for treating coprostasis, which controls the technical parameter strictly during the manufacture process of selecting, crushing,drying, graining, mixing, putting into capsule in order to ensure the stability of non-water barbaloin, reduce the loss of non-water barbaloin during the manufacture process. The production is with higher contain that cannot reduce by time extend.

Description

【Technical field】 [0001] The invention relates to a production process of capsules for treating constipation, and belongs to the field of manufacturing aloe products of a specific origin and a specific variety for soothing the intestines and laxatives. 【Background technique】 [0002] At present, there are many aloe vera products on the market for laxatives, but there are not many effective products that can really promote bowel movements. Most products are only effective for patients with mild constipation, and are not effective for patients with slightly heavier constipation, especially middle-aged and elderly patients with habitual constipation. The effective active ingredient of aloe vera products for laxative is anhydrous aloin, which can effectively promote rectal peristalsis, increase intestinal motility and stimulate intestinal cavity to secrete body fluid, moisten the colon, so as to achieve the purpose of defecation. However, the chemical structure of anhydrous alo...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/896A61K9/48A61P1/10
Inventor 余祥彬
Owner FUZHOU CHENXING PHARMA