Unlock instant, AI-driven research and patent intelligence for your innovation.

Intralesional treatment of psoriasis

A technique for psoriasis and damaged areas, applied in the field of treatment of psoriasis damaged areas, can solve problems such as failure to recognize the greater effect of serotonin

Inactive Publication Date: 2008-08-06
费城健康与教育公司 +1
View PDF5 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, these authors provide an important set of information but fail to recognize the larger role of serotonin in the regulation of T cell-dependent responses

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0021] The present invention relates to the treatment of the autoimmune disease psoriasis in human patients. Therapeutic regimens include administering to the patient, either directly or indirectly, antagonists of the interaction of serotonin that interacts with serotonin receptors. In one aspect, phenothiazine compounds capable of inhibiting, either directly or indirectly, the interaction of serotonin with serotonin receptors are used. A preferred phenothiazine compound for use in the treatment regimen of the present invention is fluperazine or a derivative thereof. A preferred route of administration of the fluperazine compound is to deliver the compound directly to the psoriatic lesion, ie, the lesion area delivers the compound to the patient.

[0022] Compositions and methods describing the inhibition of the interaction of serotonin with serotonin receptors are disclosed in US Patent Application Publication No. 2003 / 0100570. Furthermore, the use of fluperazine and its de...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The present invention includes the treatment of psoriasis in a human comprising the intralesional administration of a phenothiazine, preferably fluphenazine, to a psoriatic plaque in the patient.

Description

Background of the invention [0001] Psoriasis is a common human autoimmune disease that affects the skin. Psoriasis can appear as minor lesions on one area of ​​the body, or it can affect most skin surfaces, joints and eyes. Discontinuous lesions on the skin are commonly referred to as psoriatic plaques. The true cause of psoriasis is unknown, but it is generally accepted that the disease has a genetic and an environmental basis. Psoriatic skin is known to have a much higher skin turnover rate than non-psoriatic skin, which occurs approximately every 28 days, while the former occurs in as little as 4 days. Although a variety of therapies for the treatment of psoriasis are commercially available, most treatments require continuous application to the affected area and have significant side effects. [0002] Serotonin (also known as serotonin or 5-HT) is a neurotransmitter intimately involved in the pathophysiology and treatment of many neuropsychiatric disorders. Serotonin ac...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/13A61K31/573A61K31/5415A61K31/5377A61K31/4245A61K31/437A61K31/4375A61K31/4439A61K31/444A61K31/445A61K31/496A61K31/505A61K31/517A61K31/519A61K31/55A61K45/00A61P1/04A61P3/10A61P13/00A61P15/00A61P17/06A61P19/02A61P21/00A61P21/04A61P25/00A61P27/02A61P29/00A61P37/02C07K14/705C12Q1/02G01N33/15G01N33/50G01N33/566
CPCC07K14/70571A61K31/5377A61K31/437A61K31/519A61K9/0009A61K31/496A61K31/573G01N33/5008A61K31/445G01N2510/00A61K45/06A61K9/0019A61K31/4439A61K31/444A61K31/505G01N33/5011A61K31/4375A61K31/5415A61K31/4245G01N33/566G01N33/505A61K31/517A61K31/55A61P1/04A61P13/00A61P15/00A61P17/06A61P19/02A61P21/00A61P21/04A61P25/00A61P27/02A61P29/00A61P37/02A61P3/10A61K2300/00
Inventor S·罗斯R·莫尔B·A·詹姆森
Owner 费城健康与教育公司
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com