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Method for preparing lactic acid

A technology of lactic acid and metal elements, applied in chemical instruments and methods, carboxylate preparation, organic compound preparation, etc., can solve the problems of high price of ion exchange resin, achieve good catalytic performance, mild reaction conditions, and easy separation Effect

Inactive Publication Date: 2008-09-17
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Using a specific anion exchange resin, the highest single-pass yield of lactic acid can exceed 80%, but the ion exchange resin is expensive, and a large amount of NaOH and H are used in the regenerative washing process. 2 SO 4 Inorganic acids and bases

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0034] In an ice bath, 4.86g TiCl 4 and 8.04 g ZrOCl 2 ·8H 2 O was dissolved in deionized water to prepare a mixed solution with a concentration of 0.5M. The mixed solution was dropped into 25% ammonia solution with a mass concentration. Control the pH at the end point of the addition to be 9. The resulting precipitate was aged at room temperature for 12 h, washed with deionized water until the AgNO 3 No Cl ions were detected and dried at 120°C for 16h. The dried precipitate was ground and calcined at 500° C. for 6 hours to obtain a composite metal oxide catalyst. Add 3 g of catalyst and 400 ml of 10 g / L glucose aqueous solution in a 1 L closed high-pressure stirred reactor. The reaction conditions are 1.7 MPa and 180° C., and the stirring speed is 400 rpm. After reacting for 4 hours, the material was rapidly cooled and discharged, and the conversion rate of glucose obtained in the product was analyzed by high performance liquid chromatography (HPLC) was 99.54%, and the...

example 2

[0036] 4.76g TiCl in an ice bath 4 and 9.72g Al(NO 3 ) 3 9H 2 O was dissolved in deionized water, and a mixed solution with a concentration of 2M was prepared and then dropped into a 1M ammonium bicarbonate solution. Control the pH value of the end point of the dropwise addition to be 8. The resulting precipitate was aged at room temperature for 12 h and washed with deionized water until the AgNO 3 No Cl ions detected. Dry at 120°C for 16h. The dried precipitate was calcined at 500° C. for 6 h to obtain a composite metal oxide catalyst. Add 1 g of catalyst and 400 ml of 25 g / L glucose aqueous solution in a 1 L closed high-pressure stirred tank. The reaction conditions are 2.5 MPa and 220° C., and the stirring speed is 400 rpm. After reacting for 20 hours, the material was rapidly cooled and discharged, and the conversion rate of glucose obtained in the product was analyzed by high performance liquid chromatography (HPLC) was 98.71%, and the yield of lactic acid was 18....

example 3

[0038] 9.38g Al(NO 3 ) 3 9H 2 O and 8.04 g ZrOCl 2 ·8H 2 O was dissolved in deionized water, and a mixed solution with a concentration of 0.5M was prepared and slowly added dropwise to the stirred 1M ammonium carbonate solution. Control the pH value of the end point of the dropwise addition to be 8. After aging for 12 h at room temperature, the obtained precipitate was washed with deionized water until AgNO 3 No Cl ions were detected, dried at 120°C for 16h and then calcined at 500°C for 6h to obtain a composite metal oxide catalyst. Add 4 g of catalyst and 400 ml of 10 g / L glucose aqueous solution in a 1 L closed high-pressure stirred tank. The reaction conditions are 1.7 MPa and 180° C., and the stirring speed is 400 rpm. After reacting for 2 hours, the material was rapidly cooled and discharged, and the conversion rate of glucose obtained in the product was analyzed by high performance liquid chromatography (HPLC) was 97.19%, and the yield of lactic acid was 32.75%. ...

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PUM

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Abstract

The invention relates to a method of preparing lactic acid. The method comprises the following steps: firstly, compound metallic oxide catalyst is prepared by adopting a settling method or a sol-gel method; secondly, the compound metallic oxide is utilized to catalyze and hydrolyze glucose to prepare the lactic acid. In the method, the reaction conditions are mild, and the yield rate of the lactic acid is more than 39 percent. A environment-protecting solid catalyst is adopted, thereby being easily separated and regenerated; the glucose which is the reaction raw material can be obtained from reproducible biomass resources, thereby complying with the green requirements without environmental pollution.

Description

technical field [0001] The invention relates to a method for producing lactic acid. Especially the method for preparing lactic acid by catalyzing the hydrolysis of glucose with complex metal oxides. Background technique [0002] With the increasingly serious resource crisis, the development of renewable resource utilization technology has been paid more and more attention. Lactic acid is an important platform compound that can generate a variety of derivatives. It has a long history of application in food, medicine, light industry, chemical industry and other industries. In recent years, as people pay more attention to the biodegradable plastic polylactic acid, the role and demand of lactic acid will definitely increase a lot. As a green platform compound, renewable raw materials and green production are two important factors. The traditional methods for preparing lactic acid mainly include biological fermentation and chemical synthesis. The bio-fermentation method has ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07C59/08C07C51/00B01J21/06
Inventor 陈丰秋曾炜程党国詹晓力
Owner ZHEJIANG UNIV