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Chinese medicine preparation for treating cardiac arrhythmia and preparation thereof

A technology of traditional Chinese medicine preparation and arrhythmia, which is applied in the directions of medical formula, pill delivery, drug combination, etc., and can solve problems such as side effects and restrictions on wide application

Inactive Publication Date: 2008-11-12
QIANNIANJIAN MEDICINE RES & DEV CO LTD BAOTOU CITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Arrhythmia is a serious and complicated heart disease. There is no specific drug for treatment. In recent years, many new antiarrhythmic drugs have been developed, but most of them are western medicine preparations. Many patients with severe arrhythmia can improve their symptoms after treatment. However, the serious side effect of this type of drug: arrhythmogenic effect, has seriously limited its wide application in clinical practice.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Example 1: Panax notoginseng total saponins 50g, American ginseng 250g, pearl 100g, honey 600g, microcrystalline cellulose 100g

[0037] American ginseng and pearls were crushed and passed through 80-mesh sieve, then superfinely pulverized into micropowder by fluidized bed airflow, added notoginseng total saponins, then added microcrystalline cellulose, mixed evenly, then added honey, stirred evenly, and made 1000g Honey pills.

Embodiment 2

[0038] Example 2: 20 g of Panax notoginseng saponins, 100 g of American ginseng, 40 g of pearls, 152 g of microcrystalline cellulose, 40 g of low-substituted hydroxypropylmethyl cellulose, 12 g of sodium lauryl sulfate, 15 g of starch, 3 g of lactose, and magnesium stearate 3g, talcum powder 3g, ethanol 200ml, RT coating agent 12g

[0039]American ginseng and pearls were crushed and passed through a 80-mesh sieve, and then ultrafinely pulverized into micropowder by fluidized bed airflow. Sodium sulfate mixed powder (10:3) 17.3g, cross 80 mesh sieves, after mixing evenly, granulate with 10% starch slurry (pulling slurry), after drying, add low-substituted hydroxypropyl methylcellulose and dodecyl Alkyl sodium sulfate mixed powder (10:3) 34.7g, and lactose, magnesium stearate, talcum powder, mixed evenly, pressed into 1000 tablets, coated with film, to obtain.

Embodiment 3

[0040] Example 3: Panax notoginseng total saponins 20g, American ginseng 100g, pearl 40g, microcrystalline cellulose 20g, mannitol 30g, sucrose 130g, starch 15g, lactose 15g,

[0041] American ginseng and pearls were crushed separately and passed through a 80-mesh sieve, then superfinely pulverized into micropowder by fluidized bed airflow, adding Panax notoginseng saponins, microcrystalline cellulose, mannitol, sucrose, lactose, passed through a 80-mesh sieve, and mixed After homogenization, granulate with 10% starch slurry (flushing), and dry to obtain granules.

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PUM

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Abstract

The invention belongs to the medical traditional Chinese medicine preparing field, and in particular provides a traditional Chinese medicine preparation for treating arrhythmia, as well as a method for making the same. The preparation is mainly made from panax notoginseng saponins, American ginseng and pearls. The preparation can be tablets, granules, hard capsules, soft capsules, powder injection, pills, oral liquid, aerosol, injection solution, dropping pills, etc. Compared with the prior art, the preparation is clear in formula composition and obvious in efficacy, and mainly plays a role in removing blood stasis, dredging veins, supplementing Qi, promoting blood circulation, calming heart and tranquilizing mind. Meanwhile, the preparation method is simple in process and convenient for controlling quality. The preparation is low in cost, and can be really applied to angina pectoris which is caused by Qi deficiency, blood stasis and heart vessel stasis, and marked by chest stuffiness, chest distress, palpitation, short breath, lassitude, dark purple complexion, mauve pale tongue, weak and uneven pulse, etc.

Description

Technical field: [0001] The invention belongs to the field of medical preparation of traditional Chinese medicines, in particular to a traditional Chinese medicine preparation for treating arrhythmia and a preparation method thereof. Background technique: [0002] Arrhythmia (Arrhythmia) belongs to the category of palpitations in traditional Chinese medicine. Symptoms include palpitations, shortness of breath, and alternate pulses. It is mainly due to insufficient Yang Qi, deficiency of Yin and blood, heart failure, or phlegm retention, stagnation of blood, and poor heart arteries. There are many causes of arrhythmia, such as coronary heart disease, myocardial infarction, cardiomyopathy, valvular disease, and chronic conduction system disease of the heart. In addition, electrolyte disturbance, ischemia, oxygen hemodynamic disturbance, metabolic Disorders, drugs or poisons can be the cause of arrhythmia or recurrence. Others such as fatigue, mental stress, emotional agitation...

Claims

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Application Information

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IPC IPC(8): A61K36/258A61K9/08A61K9/10A61K9/12A61K9/14A61K9/16A61K9/20A61K9/48A61K47/10A61K47/12A61K47/24A61K47/26A61K47/34A61K47/40A61K47/38A61K47/42A61K47/44A61P9/06A61K35/56
Inventor 于得才李卫民朱贺年贾金良
Owner QIANNIANJIAN MEDICINE RES & DEV CO LTD BAOTOU CITY
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