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Chinese medicinal composition for treating coronary disease, stenocardia, arrhythmia and preparation method thereof

A technology of arrhythmia and composition, which is applied in the field of arrhythmia traditional Chinese medicine composition and its preparation, angina pectoris, and treatment of coronary heart disease, which can solve problems such as unsatisfactory effects and repeated illnesses

Active Publication Date: 2012-09-12
广东宏兴集团股份有限公司宏兴制药厂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many Chinese and Western patent medicines for the treatment of coronary heart disease, angina pectoris, and arrhythmia on the market. Although most of them have a certain therapeutic effect, the effect is not ideal, and the condition recurs after stopping the medicine.

Method used

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  • Chinese medicinal composition for treating coronary disease, stenocardia, arrhythmia and preparation method thereof
  • Chinese medicinal composition for treating coronary disease, stenocardia, arrhythmia and preparation method thereof
  • Chinese medicinal composition for treating coronary disease, stenocardia, arrhythmia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0073] Embodiment 1: the preparation of pill

[0074] Take 5400 parts by weight of Panax notoginseng and grind it into a coarse powder, extract it with 90% ethanol under reflux, filter, adjust the pH value of the filtrate to 8.0 with concentrated ammonia test solution, leave it overnight, filter, concentrate the filtrate under reduced pressure until it has no ethanol smell, use Adjust the pH value to 6.0 with 30% hydrochloric acid solution, leave it overnight, filter, shake the filtrate with ether, discard the ether solution, extract with n-butanol saturated with water, combine the n-butanol solution, recover n-butanol under reduced pressure, and Vacuum-dried at 60°C to prepare Panax notoginseng saponins for later use; take buffalo horn thin slices, add 10 times the amount of water, decoct three times, 8 hours each time, add water at any time during the decoction process, combine decoctions, filter, and concentrate the filtrate into Thick cream, dried at 80°C to obtain buffalo...

Embodiment 2

[0075] Embodiment 2: the preparation of capsule

[0076] Take 450 parts by weight of Panax notoginseng and grind it into coarse powder, extract it with 60% ethanol under reflux, filter, adjust the pH value of the filtrate to 8.0 with concentrated ammonia test solution, leave it overnight, filter, concentrate the filtrate under reduced pressure until it has no ethanol smell, use Adjust the pH value to 6.0 with 20% hydrochloric acid solution, leave it overnight, filter, shake the filtrate with ether, discard the ether solution, extract with n-butanol saturated with water, combine the n-butanol solution, recover n-butanol under reduced pressure, and Vacuum-dried at 70°C to obtain total saponins of Panax notoginseng for later use; take thin slices of buffalo horn, add 8 times the amount of water, decoct three times, 7 hours each time, add water at any time during the decoction process, combine the decoction, filter, and concentrate the filtrate into Thick paste, dried at 60°C to o...

Embodiment 3

[0077] Embodiment 3: the preparation of tablet

[0078] Take 3000 parts by weight of Panax notoginseng and crush it into coarse powder, extract it with 70% ethanol under reflux, filter, adjust the pH value of the filtrate to 8.0 with concentrated ammonia test solution, leave it overnight, filter, concentrate the filtrate under reduced pressure until it has no ethanol smell, use Adjust the pH value to 6.5 with 15% hydrochloric acid solution, leave it overnight, filter, shake the filtrate with ether, discard the ether solution, extract with n-butanol saturated with water, combine the n-butanol solution, recover n-butanol under reduced pressure, and Vacuum-dried at 60°C to prepare Panax notoginseng saponins for later use; take buffalo horn slices, add 5 times the amount of water, decoct three times, 10 hours each time, add water at any time during the decoction process, combine the decoction, filter, and concentrate the filtrate into Thick cream, dried at 80°C to obtain buffalo h...

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PUM

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Abstract

The invention provides a Chinese medicine composition used for curing coronary heart disease, angina and arrhythmia and a preparation method thereof. The Chinese medicine composition consists of components as follows: 5 to 20 weight percentage of musk, 12 to 50 weight percentage, 30 to 120 weight percentage of bear gall, 15 to 60 weight percentage of toad venom, 30 to 120 weight percentage of pearl, 40 to 160 weight percentage of borneol, 1500 to 15000 weight percentage of panax pseudo-ginseng wallich, 150 to 600 weight percentage of ginseng and 25 to 100 weight percentage of the dry extract of buffalo horn. The Chinese medicine composition of the invention can improve blood circulation, dilate coronary arteries, increase the blood flow volume of coronary artery, improve the blood-supply of cardiac muscle, eliminate angina, prevent cardiac arrhythmia, lower blood-fat and improve cardiac function.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating coronary heart disease, angina pectoris and arrhythmia and a preparation method thereof. Background technique [0002] Due to coronary atherosclerosis, the heart disease caused by the obstruction of blood supply to the heart, referred to as coronary heart disease, is a common and frequently-occurring disease among middle-aged and elderly people, and it seriously endangers people's health. According to the occurrence and development of coronary heart disease, its pathological basis is generally believed to be due to abnormal blood lipid metabolism, thrombus formation, and abnormal metabolism of blood vessel walls, resulting in atherosclerosis in the coronary artery intima, resulting in narrowing of the coronary artery lumen, reduced blood flow, and formation of myocardial infarction. ischemia and hypoxia. Clinica...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/258A61K9/14A61K9/16A61K9/20A61K9/48A61P9/06A61P9/10A61K31/045A61K35/32A61K35/413A61K35/55A61K35/56A61K35/618A61K35/65
Inventor 李志勇张惜强赖怀恩苏和明郑少鑫杨宝如魏健林光耀
Owner 广东宏兴集团股份有限公司宏兴制药厂
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