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Dripping pill for treating hepatitis and preparation method thereof

A technology for dropping pills and hepatitis, which is applied in the direction of pill delivery, medical preparations containing active ingredients, antiviral agents, etc. It can solve the problems of capsule skin aging and health effects, and achieve easy quality control, small side effects, and bioavailability high effect

Inactive Publication Date: 2009-07-22
BEIJING TIANKE RENXIANG MEDICAL SCI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Gelatin is mostly used as the capsule body material for the preparation of capsules. Due to the characteristics of gelatin and the preparation technology, the outer skin of the capsule is prone to aging during the storage of capsules, which will produce certain insoluble substances in the human body. Residues in the human body will have a certain impact on the health of the human body. Therefore, many international and domestic medical workers are constantly conducting in-depth research in order to seek to improve this phenomenon.

Method used

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  • Dripping pill for treating hepatitis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] (1) Take 300g sorrel 300g 400g Pinggu, add water and decoct twice, the first time for 2 hours, the second time for 1 hour, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.20-1.25 (20°C) The clear ointment is spray-dried to obtain dry powder (medicinal ingredient);

[0024] (2) Put 600 g of polyethylene glycol (4000) in a heating container and heat it to melt while stirring, then gradually add medicinal powder and stir until the molten liquid of medicinal powder and matrix is ​​obtained, and set aside;

[0025] (3) Adopt a self-made or general-purpose dripping pill machine, and adjust the temperature control system of the dripping pill machine so that the temperature of the dripper of the dripping pill machine is kept at (75-85) °C, and the temperature gradient of the condensing agent is (30) ~20)℃→(5~-5)℃;

[0026] (4) When the temperature of the dripper and the condensing agent of the dripping pill machine have been stabilized in...

Embodiment 2

[0029] (1) Take 300g sorrel 300g 400g Pinggu, add water and decoct twice, the first time for 2 hours, the second time for 1 hour, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.20-1.25 (20°C) The clear ointment is spray-dried to obtain dry powder (medicinal ingredient);

[0030] (2) Put 300g of polyethylene glycol (6000) and 30g of polyethylene glycol (20000) and 15g of sodium stearate in a heating container and heat it to melt while stirring, then gradually add medicinal powder in stages and stir, Until the molten liquid of medicinal material powder and matrix is ​​obtained, set aside;

[0031] (3) Adopt a self-made or general-purpose dripping pill machine, and adjust the temperature control system of the dripping pill machine so that the temperature of the dripper of the dripping pill machine is kept at (75-85) °C, and the temperature gradient of the condensing agent is (30) ~20)℃→(5~-5)℃;

[0032] (4) When the temperature of the dri...

Embodiment 3

[0036] (1) Take 300g sorrel 300g 400g Pinggu, add water and decoct twice, the first time for 2 hours, the second time for 1 hour, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.20-1.25 (20°C) The clear ointment is spray-dried to obtain dry powder (medicinal ingredient);

[0037] (2) Put Tween-801g, polyethylene glycol (6000) 250g, polyethylene glycol (4000) 150g, in the heating container and heat to melt while stirring, then gradually add the medicinal material powder and stir, Until the molten liquid of medicinal material powder and matrix is ​​obtained, set aside;

[0038] (3) Adopt a self-made or general-purpose dripping pill machine, and adjust the temperature control system of the dripping pill machine so that the temperature of the dripper of the dripping pill machine is kept at (75-85) °C, and the temperature gradient of the condensing agent is (30) ~20)℃→(5~-5)℃;

[0039] (4) When the temperature of the dripper and the condensi...

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Abstract

The invention discloses a dripping pill for treating hepatitis and a preparation method thereof. The traditional Chinese medicine dripping pill is prepared by taking traditional Chinese medicines as initial raw materials. The prior technology is combined with modern science and technology and used for preparing traditional Chinese medicine preparation in order to achieve the requirements of high treatment effect and small dosage, so that the technical level of processing of the traditional Chinese medicines is greatly improved; the production efficiency and the quality of the traditional Chinese medicine preparation are improved; and the development of the dripping pill is promoted. The preparation method for the drilling pill has the advantages of simple equipment, easy operation, short production period, simple production process, low cost, non dust pollution, conservation of raw materials and auxiliary materials, and the like, has stable quality and good controllability, and is convenient to carry.

Description

technical field [0001] The invention belongs to the field of Chinese patent medicine drop pill preparations, in particular relates to a drop pill for treating hepatitis, and also relates to a preparation method of the drop pill. Background technique [0002] Jinsuanping Syrup is recorded in the eighth volume of the Ministry of Health's drug standards for traditional Chinese medicine prescriptions. It has the functions of clearing away heat and detoxification, promoting dampness and reducing jaundice, restoring liver function and reducing transaminase. The oral preparation is a common oral pharmaceutical preparation clinically used for acute icteric hepatitis, chronic hepatitis, and severe hepatitis. [0003] Gelatin is mostly used as the capsule body material for the preparation of capsules. Due to the characteristics of gelatin and the preparation technology, the outer skin of the capsule is prone to aging during the storage of capsules, which will produce certain insoluble...

Claims

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Application Information

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IPC IPC(8): A61K36/80A61K9/20A61K47/34A61K47/36A61K47/40A61P1/16A61P31/14A61P31/20
Inventor 王丽娟
Owner BEIJING TIANKE RENXIANG MEDICAL SCI TECH