Unlock instant, AI-driven research and patent intelligence for your innovation.

A medicament composition for preventing and treating osteoporosis and the preparation thereof

A technology for osteoporosis and composition, which is applied in the field of traditional Chinese medicine, can solve the problems of high price, unpopular use, and increased risk of endometrial cancer and ovarian cancer, etc., and achieves convenience in taking, stable extraction and molding process, and extraction And the effect of mature molding process

Inactive Publication Date: 2011-06-22
河北大学附属医院 +1
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, estrogen replacement therapy (ERT) is currently the most important method for the prevention and treatment of postmenopausal osteoporosis, but recent studies have shown that ERT can easily increase the risk of breast cancer, endometrial cancer and ovarian cancer in postmenopausal women
In addition, most of the most common osteoporosis drugs used clinically are developed by developed countries, which are expensive and cannot be widely used. Therefore, finding other drugs and methods to prevent and treat osteoporosis is an important direction of current research work
However, there is no report on combining them in a certain ratio as a drug

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A medicament composition for preventing and treating osteoporosis and the preparation thereof
  • A medicament composition for preventing and treating osteoporosis and the preparation thereof
  • A medicament composition for preventing and treating osteoporosis and the preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Embodiment 1: Capsules

[0052] Soak 1000g of Epimedium, 600g of Drynaria, 500g of Chinese yam, and 500g of Poria cocos in water, decoct twice, add water 11 times the amount of raw materials for the first time, extract for 1.5 hours, add water 9 times the amount of raw materials for the second time, Extract for 1.5 hours, filter, combine the filtrates, concentrate under reduced pressure to a clear paste containing crude drug 2.5g / ml (relative density 1.10-1.15, 50°C), add 30g beta-cyclodextrin, spray dry to obtain dry extract powder, and then Add 30 g of soybean isoflavones and 50 g of oyster (calcined), mix well, pulverize, sieve and granulate, pack into capsules, and make 1000 capsules.

Embodiment 2

[0053] Embodiment 2, capsule

[0054] Soak 800g of Epimedium, 400g of Rhizoma Drynariae, 200g of Chinese yam, and 300g of Poria cocos in water, decoct twice, add water 11 times the amount of raw materials for the first time, extract for 1.5 hours, add water 9 times the amount of raw materials for the second time, Extract for 1.5 hours, filter, combine the filtrates, concentrate under reduced pressure to a clear paste containing crude drug 2.5g / ml (relative density 1.10-1.15, 50°C), add 30g beta-cyclodextrin, spray dry to obtain dry extract powder, and then Add 10 g of soybean isoflavones and 20 g of oyster (calcined), mix well, pulverize, sieve and granulate, pack into capsules, and make 1000 capsules.

Embodiment 3

[0055] Embodiment 3, capsule

[0056] Soak 1200g of Epimedium, 800g of Rhizoma Drynariae, 700g of yam, and 600g of Poria cocos in water, decoct twice, add 11 times the amount of water for the first time, extract for 1.5 hours, add 9 times the amount of water for the second time, Extract for 1.5 hours, filter, combine the filtrates, concentrate under reduced pressure to a clear paste containing crude drug 2.5g / ml (relative density 1.10-1.15, 50°C), add 30g beta-cyclodextrin, spray dry to obtain dry extract powder, and then Add 50 g of soybean isoflavones and 70 g of oyster (calcined), mix well, pulverize, sieve and granulate, pack into capsules, and make 1000 capsules.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a medicament composition for preventing and treating osteoporosis and the preparation thereof, wherein, the composition is formed by extracting and processing traditional Chinese medicine materials of Epimedium Herb, Fortune's Drynaria Rhizome, Isoflavones, cinnamomvine, Glabrous Greenbrier Rhizome, calcined oyster shell, or the like.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a pharmaceutical composition for preventing and treating osteoporosis and a preparation method thereof. Background technique [0002] Osteoporosis is a metabolic bone disease characterized by low bone mass, bone fragility, degradation of the bone tissue microenvironment, and increased likelihood of fracture. With the advent of an aging society, osteoporosis has become a public health problem that cannot be ignored, threatening the health of middle-aged and elderly people and seriously affecting their quality of life. At present, the Chinese government has listed osteoporosis, diabetes and senile dementia as the three key senile diseases. Early prevention and treatment of osteoporosis has become an urgent task in the medical field. [0003] Currently, drugs for the prevention and treatment of osteoporosis are mainly divided into two categories, namely, bone resorption ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8945A61K9/48A61P19/10A61K31/352A61K35/56A61K35/618
Inventor 王鹏张金超孙静张晓周申士刚
Owner 河北大学附属医院