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Pharmaceutical composition for treating heart cerebrovascular disease

A technology of cardiovascular and cerebrovascular diseases and compositions, which is applied in the direction of cardiovascular system diseases, drug combinations, active ingredients of hydroxyl compounds, etc., and can solve problems such as refractory treatment, chemical drug withdrawal recurrence, toxic and side effects, etc.

Active Publication Date: 2012-01-04
JILIN ZIXIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, many chemical drugs are used in the treatment of the above-mentioned cardiovascular and cerebrovascular diseases, but they are difficult to treat due to problems such as drug withdrawal, recurrence and toxic side effects. The ideal drug for the treatment of the above diseases has yet to be developed

Method used

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  • Pharmaceutical composition for treating heart cerebrovascular disease
  • Pharmaceutical composition for treating heart cerebrovascular disease
  • Pharmaceutical composition for treating heart cerebrovascular disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0065] The preparation of embodiment 1 capsule of the present invention

[0066] 50g total flavonoids of Caulis Spatholobus, 30g total glucosides of paeony, 40g turmeric sesquiterpenes, 60g tangerine peel essential oil, 50g ethanol extract of medlar, 60g water extract of Radix Ophiopogon japonicus, 10g amygdalin, 30g safflower water extract, Panax notoginseng total saponins 50g, woody essential oil 20g, sealwort alcohol extract 150g, borneol 5g, salvia miltiorrhiza 60g alcohol extract, balm essential oil 30g, chuanxiong ferulic acid 20g, calamus essential oil 40g, ginseng total saponins 20g.

[0067] Add conventional auxiliary materials for preparing capsules, granulate and pack into capsules.

[0068] The above-mentioned various extracts in the present invention can be obtained by any extraction method in the prior art. Preferably:

[0069] Total flavonoids of Caulis Spatholobus: Weigh an appropriate amount of raw materials, extract with 50%-90% ethanol under reflux for 1-3...

Embodiment 2

[0085] The preparation of embodiment 2 tablet of the present invention

[0086] Total flavonoids of Caulis Spatholobus 100g, total glucosides of paeony 65g, turmeric sesquiterpenes 95g, tangerine peel essential oil 105g, wolfberry alcoholic extract 100g, Ophiopogon japonicus water extract 130g, amygdalin 30g, safflower water extract 65g, Panax notoginseng total saponins 100g, woody essential oil 60g, sealwort alcohol extract 225g, borneol 27.5g, salvia miltiorrhiza 130g alcohol extract, balm essential oil 90g, chuanxiong ferulic acid 60g, calamus essential oil 70g, total ginsenosides 60g.

[0087] Add 4487.5 g of conventional adjuvants for tablet preparation to make 20000 tablets, each weighing 0.3 g.

Embodiment 3

[0088] The preparation of embodiment 3 granules of the present invention

[0089] 150g of total flavonoids of Gallis Spatholobus, 100g of total glucosides of paeony, 150g of turmeric sesquiterpenes, 150g of tangerine peel essential oil, 150g of wolfberry alcoholic extract, 200g of Radix Ophiopogon japonicus water extract, 50g of amygdalin, 100g of safflower water extract, Panax notoginseng total saponins 150g, woody essential oil 100g, sealwort alcohol extract 300g, borneol 50g, salvia miltiorrhiza 200g alcohol extract, balm essential oil 150g, chuanxiong ferulic acid 100g, calamus essential oil 100g, total ginsenosides 100g.

[0090] Add conventional excipients for tablet preparation to make granules.

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Abstract

The invention relates to a pharmaceutical composition for treating heart cerebrovascular disease, belonging to a traditional Chinese medicine composition. The pharmaceutical composition contains active substances based on the parts by weight: 5-15 parts of spatholobus suberectus total flavanone, 3-10 parts of radix paeoniae rubra total glycoside, 4-15 parts of radix curcumae sesquiterpene, 6-15 parts of tangerine peel essential oil, 5-15 parts of barbary wolfberry fruit alcohol extract, 6-20 parts of dwarf lilyturf root water extract, 1-5 parts of amygdalin, 3-10 parts of safflower water extract, 5-15 parts of panax notoginseng saponin, 2-10 parts of costustoot essential oil, 15-30 parts of rhizoma polygonati alcohol extract, 0.5-5 parts of borneol, 6-20 parts of salvia miltiorrhiza alcohol extract, 3-15 parts of rosewood heart wood essential oil, 2-10 parts of ligusticum wallichii ferulic acid, 4-10 parts of rhizoma acori graminei essential oil and 2-10 parts of ginseng total saponin. The pharmaceutical composition is used for treating angina caused by coronary sclerosis and diseases such as chest distress and shortness of breath, insufficient heart-qi, blood stasis pain, etc.

Description

technical field [0001] The invention belongs to a traditional Chinese medicine composition, especially for treating angina pectoris caused by coronary arteriosclerosis, chest tightness, shortness of breath, heart-qi deficiency, and blood stasis pain. Background technique [0002] Coronary heart disease is a kind of heart disease caused by coronary artery organic, atherosclerosis or dynamic vasospasm, stenosis or obstruction, myocardial ischemia and hypoxia, angina pectoris or myocardial necrosis, myocardial infarction, and is the most common heart disease. Heart disease refers to myocardial dysfunction and / or organic disease caused by coronary artery stenosis and insufficient blood supply. Cerebral arteriosclerosis is a part of systemic arteriosclerosis, and it is also the main pathogenesis basis of acute cerebral blood circulation, especially cerebral ischemic attack. Hyperviscosity is the excessive viscosity of blood, which is caused by the aggregation of red blood cells ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P9/10A61K31/045
Inventor 殷金龙郭春生李宝芝祖春香
Owner JILIN ZIXIN PHARMA