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Preparation method of Houttuynia cordata injection

A grass injection, injection technology, applied in the field of medicine, can solve problems such as loss of economic resources and unemployment

Inactive Publication Date: 2010-01-20
HUNAN ZHENGQING PHARM GRP CO LTD +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

According to incomplete statistics, the suspension has led to the closure of most of the production enterprises that mainly produce Houttuynia cordata injection products, tens of thousands of employees have been or are facing unemployment, and hundreds of thousands of farmers who grow Houttuynia cordata will lose their source of income

Method used

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  • Preparation method of Houttuynia cordata injection
  • Preparation method of Houttuynia cordata injection
  • Preparation method of Houttuynia cordata injection

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0177] Example 1: Preparation method of Houttuynia cordata injection containing β-cyclodextrin derivatives

[0178] Take 2000g of fresh Houttuynia cordata for steam distillation, collect 2000ml of initial distillate, and then carry out redistillation, collect 1000ml of redistillate, add 4g of hydroxypropyl-β-cyclodextrin and 7g of sodium chloride, mix well, and inject Make it into 1000ml with water, filter, pot, and sterilize.

Embodiment 2

[0179] Example 2: Preparation method of Houttuynia cordata injection containing β-cyclodextrin derivatives

[0180] Take 5000g of fresh Houttuynia cordata for steam distillation, collect 5000ml of initial distillate, and then carry out redistillation, collect 2500ml of redistillate, add 12g of hydroxypropyl-β-cyclodextrin and 17.5g of sodium chloride, mix well, add Water for injection is made into 2500ml, filtered, potted and sterilized.

Embodiment 3

[0181] Example 3: Preparation method of Houttuynia cordata injection containing β-cyclodextrin derivatives

[0182] Take 2000g of fresh Houttuynia cordata for steam distillation, collect 2000ml of initial distillate, and then redistill, collect 1000ml of double distillate, add 10g of hydroxypropyl-β-cyclodextrin and 7g of sodium chloride, mix well, and inject Make it into 1000ml with water, filter, pot, and sterilize.

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Abstract

The invention discloses a Houttuynia cordata injection and a preparation method thereof, and the Houttuynia cordata injection is prepared by the following method: taking fresh Houttuynia cordata, carrying out water vapor distillation, collecting initial distillate, carrying out re-distillation, collecting re-distillate, adding 4-25g of hydroxypropyl-beta-cyclodextrin and 7-9g of sodium chloride into each 1000ml of re-distillate, and preparing the injection according to the conventional method. The preparation method takes the Houttuynia cordata injection as a research object, seeks harmful components / allergic sources which can cause adverse reactions, investigates the allergic mechanism, improves the production process and successfully develops the new safe Houttuynia cordata injection.

Description

technical field [0001] The invention relates to a preparation method of an injection, in particular to a preparation method of a Houttuynia cordata injection containing a β-cyclodextrin derivative, and belongs to the technical field of medicine. Background technique [0002] Traditional Chinese medicine injection is a new dosage form of traditional Chinese medicine developed by combining modern preparation technology with traditional Chinese medicine theory. It has the advantages of quick onset and strong effect of injection, and retains the characteristics of traditional Chinese medicine to a certain extent. widely used. Since the promulgation and implementation of my country's "Drug Administration Law" in 1985, there have been 134 kinds of traditional Chinese medicine injections officially approved by the state for production and use. In the past 20 years, with the development and application of modern science and technology, the research and development and process optim...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/78A61K9/08A61P31/04A61P31/12A61P11/00A61P13/00
Inventor 李连达朱雅宁吴飞驰李贻奎袁海英仇萍张金艳吴建国滕健
Owner HUNAN ZHENGQING PHARM GRP CO LTD
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