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Extraction method of ginseng, ophiopogon root and shiandra and preparation thereof

A technology of schisandra and ginseng, applied in the field of Yiqi Fumai preparation for treating cardiovascular diseases and its preparation, achieving the effects of low cost, less dosage, and easy long-term storage

Inactive Publication Date: 2013-07-10
TIANJIN TASLY ZHIJIAO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0015] In the prior art, the production process is complicated, the cost is high, and the problems of low extraction rate have not been overcome

Method used

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  • Extraction method of ginseng, ophiopogon root and shiandra and preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0076] (1) Ginseng fibrous root coarse powder, ginseng slices, crushed into granules;

[0077] (2) Add 8 times the amount of water-containing lower alcohol, the concentration of water-containing lower alcohol is 60%, reflux extraction 6 times, each time for 3 hours, the lower alcohol is ethanol;

[0078] (3) degreasing with dichloromethane, extracting with n-butanol, concentrating the extract, merging the extract, concentrating the extract to obtain a medicinal extract, and obtaining a single extract of ginseng;

[0079] (2) Ophiopogon japonicus is extracted separately, and the extraction steps are as follows:

[0080] (1) Ophiopogon japonicus, crushed into granules;

[0081] (2) 90% ethanol percolation, the amount of ethanol is 18 times, the time is 24 hours, degreasing;

[0082] (3) Ophiopogon japonicus is dried to remove alcohol after percolation;

[0083] (4) Add 8 times the amount of water, extract 3 times at 90°C, 1 hour each time;

[0084] (5) Filtrate while hot, ad...

Embodiment 2

[0098] (1) Ginseng fibrous root coarse powder, ginseng slices, crushed into granules;

[0099] (2) Add 8 times the amount of water-containing lower alcohol, the concentration of water-containing lower alcohol is 60%; reflux extraction 6 times, each time for 3 hours, the lower alcohol is ethanol;

[0100] (3) degreasing with dichloromethane, extracting with n-butanol, concentrating the extract, combining the extract, concentrating the extract to obtain a medicinal extract, and obtaining a single extract of ginseng;

[0101] (2) Ophiopogon japonicus is extracted separately, and the extraction steps are as follows:

[0102] (1) Ophiopogon japonicus, crushed into granules;

[0103] (2) 90% ethanol percolation, the amount of ethanol is 18 times, the time is 24 hours, degreasing;

[0104] (3) Ophiopogon japonicus is dried to remove alcohol after percolation;

[0105] (4) Add 8 times the amount of water, extract 3 times at 90°C, 1 hour each time;

[0106] (5) Filtrate while hot, ...

Embodiment 3

[0120] (1) Ginseng fibrous root coarse powder, ginseng slices, crushed into granules;

[0121] (2) Add 6 times the amount of water-containing lower alcohol, the concentration of water-containing lower alcohol is 45%, reflux extraction 2 times, each time for 0.5 hours, the lower alcohol is methanol;

[0122] (3) Combine the extracts, concentrate the extracts to obtain extracts, and obtain the product as a single extract of ginseng;

[0123] (2) Ophiopogon japonicus is extracted separately, and the extraction steps are as follows:

[0124] (1) Ophiopogon japonicus, crushed into granules;

[0125] (2) 85% ethanol percolation, the amount of ethanol is 12, the time is 128 hours, degreasing;

[0126] (3) Ophiopogon japonicus is dried to remove alcohol after percolation;

[0127] (4) Add 6 times the amount of water, extract 2 times at 85°C, 0.5 hours each time;

[0128] (5) Filtrate while hot, add 0.2% activated carbon to the extract to decolorize for 2 hours, at room temperature...

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Abstract

The invention relates to a Chinese traditional medicine extraction method and a pharmaceutical preparation thereof, in particular to a preparation for treating cardiovascular diseases, tonifying qi and calming pulse and a preparation method thereof. The preparation is prepared from ginseng, ophiopogon root and shiandra.

Description

Technical field: [0001] The invention relates to a method for extracting traditional Chinese medicine and its pharmaceutical preparation, in particular to a preparation for nourishing qi and rejuvenating pulse for treating cardiovascular diseases and a preparation method thereof. Background technique: [0002] Ginseng is the root of Araliaceae Panax ginseng C.A.Mey. Its medicinal properties are sweet, slightly bitter, flat, and belong to the lung, spleen, and heart channels; Application: Syndrome of deficiency of vitality, syndrome of deficiency of lung, spleen, heart and kidney qi, syndrome of febrile disease, syndrome of qi deficiency, fluid wound, thirst and diabetes. Its chemical composition includes a variety of ginsenosides, volatile oils, amino acids, trace elements and organic acids, sugars, vitamins, etc. [0003] Ophiopogon japonicus, also known as japonica and book daicao, is a perennial evergreen herb of the genus genus Liliaceae. The fibrous roots are relati...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8968A61P5/00A61P9/02A61P9/10
Inventor 郑永锋李学敏范立君杨悦武叶正良周大峥彭可让孙建强
Owner TIANJIN TASLY ZHIJIAO PHARMA