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Perineum medicine membrane underpants for treating prostatic hyperplasia and chronic prostatitis, perineum medicine membrane patch and preparation method

A technology for chronic prostatitis and benign prostatic hyperplasia, which is applied in the direction of drug combination, medical formula, drug equipment, etc., can solve chronic prostatitis with unsatisfactory drug efficacy and surgical measures, large side effects, and little effect in the prevention and treatment of prostate diseases Function and other issues

Active Publication Date: 2012-10-10
漆瑞民
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Prostatic hyperplasia and chronic prostatitis are common diseases in middle-aged and elderly men. They are frequently refractory. Clinical symptoms include frequent urination, urgency, dribbling, dysuria, and frequent urination at night. Prostatic hyperplasia also has urinary waiting, urinary weakness, etc. Symptoms, chronic prostatitis also has cloudy urethra, damp scrotum, local perineal pain, etc. It is difficult to achieve glandular hyperplasia, hypertrophy, and inflammatory lesions with the current oral medicine at an effective concentration, and the efficacy of external suppositories is not obvious , Surgical gasification knife minimally invasive. Interventional ablation and cystostomy diversion, although postoperative symptoms can be relieved for a short time, postoperative urinary incontinence or urethral stricture may occur, and urethral dilation due to urethral stricture will cause regrowth of the gland
Not only the side effects are large, but also brings a lot of inconvenience to the life of patients
And I am not very satisfied with the above drug efficacy and surgical measures for the treatment of benign prostatic hyperplasia and chronic prostatitis
In the literature, Han Xingliang described the prostate health underwear in (application number) 96109075.8. Magnets and medicines are placed in the Qihai and other points of the abdomen, but it will not have any effect on the prevention and treatment of prostate diseases.

Method used

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  • Perineum medicine membrane underpants for treating prostatic hyperplasia and chronic prostatitis, perineum medicine membrane patch and preparation method
  • Perineum medicine membrane underpants for treating prostatic hyperplasia and chronic prostatitis, perineum medicine membrane patch and preparation method
  • Perineum medicine membrane underpants for treating prostatic hyperplasia and chronic prostatitis, perineum medicine membrane patch and preparation method

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0040] Experimental example 1. The therapeutic effect of concentrated solution of the present invention on prostatic hyperplasia in postpartum male rabbits.

[0041] Experimental material: select the concentrated solution of the present invention

[0042] Experimental method: Take 9 male white rabbits that have been mated with female white rabbits and give birth to cubs, weighing about 2000 grams, and raise them in separate cages with the female rabbits. After 18 months, each of them weighs 2800 grams~ Between 3200 grams, and randomly divided into three groups, 3 in each group, the first group is the blank control group, because the anterior and posterior genitals of the rabbits are very close, so the second and third groups of rabbits have hair removal 1.5*1.5CM around the perineum, The 3 ears of the second group were marked with red, and the concentrated solution was applied around the perineum every other day. The 3 ears of the third group were marked with black, and the co...

experiment example 2

[0048] Effect of the present invention on rat chronic prostatitis induced by Xiaozhiling injection

[0049] Experimental Materials:

[0050] Select the concentrate of the present invention

[0051] experimental method:

[0052] Take 40 male rats about 4 months old and weigh 300-400 grams for the experiment, and randomly leave 10 normal rats as the standard control of prostate tissue. After injecting Xiaozhiling in the back of the prostate, the mouth was sutured. Eight days later, the glandular tissue was dissected to observe the adhesion, nodules, and punctate calcifications between the glandular tissue and the surrounding tissue, and the microscopic observation of inflammatory cell infiltration, clusters, and interstitial fibrosis. 15 blank control groups were randomly left to smear the perineum with glycerin every day, and the remaining 15 rats were smeared with the concentrated solution of the present invention on their perineums once a day. After 20 days, they were execu...

experiment example 3

[0056] Experimental example 3: the reaction of concentrated solution of the present invention to skin allergy caused by guinea pigs

[0057] 1. Judgment and evaluation of skin allergies are shown in Table 1 and Table 2

[0058] Table 1. Scoring criteria for skin allergic reactions Table 2 Evaluation criteria for skin sensitization

[0059]

[0060] 2. Experimental materials:

[0061] 1. Concentrate of the present invention

[0062] 2.75% ethanol

[0063] 3.2,4-Dinitrochlorobenzene

[0064] 3. Experimental method:

[0065] Choose 30 white guinea pigs, male and female in half with a body weight of 250-300 grams, 10 in each group, remove the hair on both sides of the back of the guinea pigs 24 hours before giving the test drug, the range of hair removal is 30mm*30mm on both sides, the first group Give the test medicine concentrate of the present invention, the 2nd group gives the blank control group 75% ethanol, the 3rd group positive control group uses 2,4-dinitrochlorob...

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PUM

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Abstract

The invention discloses perineum medicine membrane underpants for treating prostatic hyperplasia and chronic prostatitis, and a perineum medicine membrane patch. The perineum medicine membrane underpants are prepared in a way that Ligusticum wallichii, myrrh and the like are mixed together according to certain weight proportions to extract active ingredients which are combined with auxiliary materials such as underpants. The perineum medicine membrane underpants have the efficacies of activating blood circulation, dissipating blood stasis, eliminating fat, dredging collaterals, relieving painand the like, and can be used for treating and preventing prostatic hyperplasia and chronic prostatitis. When the underpants are put on, a pocket formed by the elastic isolation cord of the underpants can hold and lift up scrotum, or the perineum medicine membrane patch is directly stuck at perineum and the medicine on the medicine membrane in close contact with the skin of the human body perineum is directly fed through cutaneous penetration.

Description

Technical field [0001] The patent of the present invention relates to an external perineal medicated underpants and perineal medicated patch for treating and preventing prostate diseases, in particular to an external transdermal drug-filmed underpants and perineal medicated patch for treating prostatic hyperplasia and chronic prostatitis. Background technique [0002] Prostatic hyperplasia and chronic prostatitis are common diseases among middle-aged and elderly men. They are frequently intractable. Clinical symptoms include frequent urination, urgency, continuous dribbling, painful urination, and frequent urination at night. Prostatic hyperplasia also has urinary waiting, urinary weakness, etc. Symptoms, chronic prostatitis also has cloudy urethra, damp scrotum, local perineal pain, etc. It is difficult to achieve glandular hyperplasia, hypertrophy, and inflammatory lesions with the current oral medicine at an effective concentration, and the efficacy of external suppositori...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61M37/00A61K36/9066A61K9/70A61P13/08
CPCA61K9/7084A61K36/489A61K36/756A41D13/1254A61M37/00A61K36/9066A61K36/236A61K36/328A61K36/284A61K36/286A61P13/08
Inventor 漆瑞民
Owner 漆瑞民