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Medicinal composition with function of improving sleeping and preparation method thereof

A technology for improving sleep and composition, which is applied in the field of pharmaceutical composition with sleep-improving function and its preparation, and can solve problems such as not being suitable for long-term use, having a large impact on the kidneys, and increasing the dosage of drugs, etc.

Inactive Publication Date: 2010-08-18
BEIJING INCREASEPHARM CORP LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Hypnotics commonly used clinically at present include benzodiazepines, barbiturates and other non-barbiturates, which are more effective in treating insomnia, but have a greater impact on the liver and kidneys, and users are prone to drug reactions. Dependence, usually need to continue to increase the dosage to maintain the effect, therefore, it is not suitable for long-term use of drugs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Take 1.5kg of Valerian Root, 1.0kg of Sour Jujube Seed, 0.9kg of Lily, and 0.6kg of Lotus Seed, add 6 times the amount of 75% ethanol to reflux and extract twice, each time for 1 hour, the filtrates are combined, the ethanol is recovered, concentrated, and dried under reduced pressure (60 ℃ , -0.08Mpa) to obtain the extract; grind the extract into fine powder, granulate with 95% ethanol, and dry to obtain.

Embodiment 2

[0026] Take 7.5kg of Valerian Root, 5kg of Jujube Seed, 4.5kg of Lily, and 3kg of Lotus Seed, add 6 times of 75% ethanol to reflux and extract twice, each time for 1-1.5 hours, combine the filtrates, recover ethanol, concentrate, and dry under reduced pressure (60°C, -0.08Mpa), to obtain the extract, pass through a 100-mesh sieve for subsequent use; take an appropriate amount of beeswax and put it in soybean oil, heat it to melt, prevent cooling to room temperature, add extract powder, appropriate amount of vitamin E, grind evenly with a colloid mill, and obtain Medicinal solution (beeswax: soybean oil: extract: vitamin E = 2:72:25:1); additionally take gelatin, glycerin, water, methyl paraben (1:0.45:1:0.001) in appropriate amount and place in a suitable container Heat to 80°C to dissolve, filter to obtain a rubber solution, and keep warm at 60°C for later use; take the above-mentioned medicinal solution and rubber solution, press them into pellets with soft capsule production...

Embodiment 3

[0028] Take 1.2kg of Valerian Root, 1.0kg of Sour Jujube Seed, 1.0kg of Lily, and 0.9kg of Lotus Seed, add 6 times the amount of 60% ethanol to reflux and extract twice, each time for 1 hour, the filtrates are combined, the ethanol is recovered, concentrated, and dried under reduced pressure (60 ℃ , -0.08Mpa) to obtain the extract; grind the extract into fine powder, granulate with 95% ethanol, and dry to obtain.

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PUM

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Abstract

The invention discloses a medicinal composition with the function of improving sleeping and a preparation method thereof. The medicinal composition is prepared from valerian, spina date seed, lily and lotus seeds in a certain weight proportion. The medicinal composition has the function of improving sleeping.

Description

technical field [0001] The invention relates to a pharmaceutical composition with the function of improving sleep and a preparation method thereof, in particular to a health food prepared from Chinese herbal medicines. Background technique [0002] People spend one-third of their time in sleep. Sleep is an important link for the body to restore, integrate and consolidate memory. It can repair and rest the tired brain and body after a day, so sleep is very important. However, with the acceleration of the pace of social life and the increase of life pressure, more and more people join the army of insomnia. According to data, in the survey of more than 10,000 people in several major cities such as Shanghai, Beijing, and Guangzhou, it was found that as many as 42.5% of those troubled by insomnia problems such as difficulty in falling asleep, easy to wake up, dreaminess, early awakening, and difficulty falling asleep after waking up, and most of them were White-collar workers en...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8967A61P25/20
Inventor 肖艳皎
Owner BEIJING INCREASEPHARM CORP LTD