Hair care compositions and methods for increasing hair diameter
A technology of hair care and composition, which is applied in the field of hair care composition, can solve problems, reduce the permeability of hair diameter increasing agents, etc., and achieve the effect of improving hair diameter increase
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0104] Example 1: Clinical Research
[0105]Compositions comprising a mixture of caffeine, niacinamide and panthenol showed a clinically significant increase in hair width relative to placebo. In this study, a water / alcohol based (25% ethanol, qs. water) scalp tonic containing 5% niacinamide, 1.5% caffeine and 0.3% D-panthenol was evaluated. The formulation also contained 0.3% hydroxypropylmethylcellulose as a thickener. In this half-head study, 1.5 mL of tonic was administered twice daily on one side of the head and 1.5 mL of placebo was administered twice daily on the other side of the head.
[0106] This is a 14-week double-blind randomized half-head controlled clinical study of women aged 18-65 (inclusive) who perceive themselves to have thinning hair. The study consisted of a 2-week pre-treatment period (placebo was administered on both sides of the head for proper product application prior to the actual treatment period), followed by a 12-week treatment period.
[0...
Embodiment 2
[0114] Example 2: Synergy Research
[0115] A mixture of caffeine, niacinamide and panthenol showed a surprising increase in the viability of metabolically stressed dermal papilla cells relative to the individual components and relative to a mixture of two of them, as shown below. The dermal papilla in normal human hair is the control center of hair diameter. Increased viability of dermal papilla cells in situ, resulting in an increase in hair diameter. Thus, increased viability of dermal papilla cells correlates with increased hair diameter.
[0116] Primary human dermal papilla cells were metabolically stressed for 48 hours in meiotic standard tissue culture medium. During this stress period, the cells were treated with the mixtures or individual components described below. After 48 hours, use Cell Titer Glo TM Kit (Promega), the metabolic activity of cells was determined according to the amount of ATP.
[0117]
[0118]
Embodiment 3
[0119] Example 3: Hair Care Composition Example
[0120] tonic
[0121]
[0122]
[0123] Preparation
[0124] The compositions of Examples A to C shown above can be prepared by any conventional method well known in the art. They can be suitably prepared as follows:
[0125] The polymeric material, if present, is dispersed in water at room temperature and mixed by vigorous stirring. Ethanol (if included) was added to the mixture. The hair diameter increasing agent, depositing agent, binder are added to the mixture while stirring to dissolve or disperse such components. The remaining ingredients such as silicone and fragrance (if included) are then added to the mixture with stirring.
[0126] Examples A to C are hair care compositions of the present invention which are especially useful for leave-on use. The composition is topically applied to the area where an increase in hair diameter is desired. These embodiments have many advantages. For example, they pr...
PUM
| Property | Measurement | Unit |
|---|---|---|
| viscosity | aaaaa | aaaaa |
| transmittivity | aaaaa | aaaaa |
| transmittivity | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
Login to View More