Medical combination for treating complications of multiple myeloma
A technology for multiple myeloma and complications, applied in drug combinations, anti-tumor drugs, pharmaceutical formulations, etc., can solve problems such as difficult treatment, and achieve the effects of less adverse reactions, low treatment, and low toxicity
Inactive Publication Date: 2011-05-11
周帆
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Problems solved by technology
[0002] Multiple myeloid is an senile disease. These patients are often accompanied by multiple systemic complications, which is the bottleneck of multiple myeloid treatment, and relapse is inevitable. For such patients, the current trend is to use thalidomide or boron Zomib and other new drugs combined with dexamethasone pulse administration, but for patients who have obvious adverse reactions after taking thalidomide and unconditionally use borzomib, as well as myeloma patients with severe organ failure or elderly patients, the treatment is still is more difficult
Method used
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Embodiment 1
[0010] Cyclophosphamide 50mg and prednisone 15mg, add conventional carrier to make tablet.
Embodiment 2
[0012] Cyclophosphamide 5 mg and dexamethasone 1.5 mg, plus conventional carriers to make tablets.
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The invention relates to a medical combination comprising cyclochosphamide and glucocorticoid which are applied simultaneously or separately for suppressing complications of multiple myeloma, and improving recurrent property, physical conditions and living quality of refractory multiple myeloma patients. Preferably, glucocorticoid adopts prednison and dexamethasone, cyclochosphamide and glucocorticoid are used in coordination, and the concentration is 10 to 30 times smaller than that of conventional dosage. The invention has the advantages of lower toxicity, less side reaction, reliable curative effect, and good tolerance compared with the conventional chemo-treatment.
Description
technical field [0001] The invention relates to the treatment of multiple myeloma complications, in particular to the application of a combination of low-dose cyclophosphamide and glucocorticoid in improving the physical condition and quality of life of patients with recurrent and refractory myeloma. Background technique [0002] Multiple myeloid is an senile disease. These patients are often accompanied by multiple systemic complications, which is the bottleneck of multiple myeloid treatment, and recurrence is inevitable. For such patients, it is currently trending to use thalidomide or boron Zomib and other new drugs combined with dexamethasone pulse administration, but for patients who have obvious adverse reactions after taking thalidomide and unconditionally use borzomib, as well as myeloma patients with severe organ failure or elderly patients, the treatment is still is more difficult. Contents of the invention [0003] The technical problem to be solved by the pres...
Claims
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Inventor 周帆候建
Owner 周帆