Traditional Chinese medicine composition for treating acute myeloblastic leukemia (AML) M1

A kind of granulocyte and leukemia technology, applied in drug combinations, antineoplastic drugs, pharmaceutical formulas, etc., can solve the problems of heavy mental burden and economy of the family and society, damage the gastrointestinal mucosa, affect the function of the heart, liver and kidney, and achieve curative effect Significant, high therapeutic effect, less recurrence effect

Inactive Publication Date: 2012-01-25
徐祖书
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this method has great side effects, such as killing and inhibiting normal hematopoietic stem cells, leading to anemia and bleeding, suppressing normal immune function, reducing body immunity, and easily merging with various infections, damaging the gastrointestinal mucosa, leading to anorexia, nausea, and vomiting. Affects heart, liver and kidney functions. No matter how high the dose is, it is impossible to completely kill leukemia cells in the body, and the residual leukemia cells are the root cause of disease recurrence.
This not only brings great pain to the patients themselves, but also causes heavy mental burden and economic losses to their families and society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] The traditional Chinese medicine composition for treating acute granulocytic AML-M1 leukemia consists of the following components:

[0058] Raw ground 15g

[0059] Moutan bark 10g

[0060] Honey roasted licorice 8 grams

[0061] Hedyotis diffusa (Diffraction Snake Grass) 25g

[0062] Imperata 14g

[0063] Ligustrum 28g

[0064] Cistanche 14g

[0065] Cordyceps 8g

[0066] Folium 20g

[0067] Wild Ophiopogon 10g

[0068] Honeysuckle 12 grams.

Embodiment 2

[0070] The traditional Chinese medicine composition for treating acute granulocytic AML-M1 leukemia consists of the following components:

[0071] Raw ground 18g

[0072] Moutan bark 12g

[0073] Roasted licorice with honey 7g

[0074] Hedyotis diffusa (Hedyotis diffusa) 32g

[0075] Imperata root 20g

[0076] Ligustrum 18g

[0077] Cistanche 20g

[0078] Cordyceps 7g

[0079] Folium 18g

[0080] Wild Ophiopogon 15g

[0081] Honeysuckle 8 grams.

Embodiment 3

[0083] The traditional Chinese medicine composition for treating acute granulocytic AML-M1 leukemia consists of the following components:

[0084] Raw ground 20g

[0085] Moutan bark 8 grams

[0086] Honey roasted licorice 6 grams

[0087] Hedyotis diffusa (Diffraction Snake Grass) 15g

[0088] Imperata root 15g

[0089] Ligustrum 25g

[0090] Cistanche 25g

[0091] Cordyceps 6 grams

[0092] 25g Folium Folium

[0093] Wild Ophiopogon 16g

[0094] Honeysuckle 16 grams.

[0095] The Ligustrum lucidum is steamed in a copper pot and bamboo cage for 30 minutes, taken out and dried in the sun, steamed again, steamed nine times and dried nine times; Stew 50 grams of rice vinegar and dry it after 30 minutes; use the leaves before flowering, that is, pick in June or July.

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PUM

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Abstract

The invention provides a traditional Chinese medicine composition for treating acute myeloblastic leukemia (AML) M1. The composition is prepared from the following components: 15-25g of radix rehmanniae, 8-16g of cortex moutan, 4-8g of honey-fried liquorice, 18-32g of oldenlandia diffusa, 14-20g of lalang grass rhizome, 18-28g of glossy privet fruit, 14-28g of herba cistanche, 4-8g of cordyceps sinensis, 15-25g of folium isatidis, 8-16g of wild radix ophiopogonis and 8-16g of honeysuckle. The medicine provided by the invention has the following functions: pertinently treating specific AML-M1, selectively inhibiting and killing immature cells, inducing leukemia cell apoptosis and having stronger pertinence and higher treatment effect; promoting differentiation and maturity of leukemia cells; regulating qi and blood and enhancing immunity; promoting recovery of normal hematopoietic function of marrows; and reducing reversion and preventing medicine resistance.

Description

[0001] The invention relates to a medicine for treating leukemia, in particular to a traditional Chinese medicine composition for treating acute granulocytic AML-M1 leukemia. Background technique [0002] Leukemia is A malignant clonal disease of hematopoietic stem cells, characterized by the diffuse proliferation of abnormal white blood cells (leukemic cells) in the bone marrow to replace normal bone marrow tissue and invade the surrounding blood, resulting in quantitative and qualitative changes in the white blood cells in the peripheral blood. The number of white blood cells in the blood is often significantly increased, but sometimes it can be normal or even decreased. Leukemic cells can extensively infiltrate various tissues and organs throughout the body, such as the liver, spleen, and lymph nodes, and often cause anemia and hemorrhage. [0003] According to the statistics of the Ministry of Health, in 2009, the annual incidence rate of leukemia in my country was 3.99 / ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61P35/02A61K36/899
Inventor 徐祖书李天喜徐晓菊徐军委徐得伟徐天祥徐军舰徐海涛徐江涛
Owner 徐祖书
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