Oil in water type citionella oil nanoemulsion and preparation method thereof
A nano-emulsion and citronella oil technology, which is applied in botany equipment and methods, pharmaceutical formulations, emulsion delivery, etc., can solve the problems of unstable physical properties of products, poor solubility of citronella pure dew, and volatile citronella essential oil, etc., to achieve The effect of improving bioavailability, good wettability, and simple preparation method
Inactive Publication Date: 2011-08-31
NORTHWEST A & F UNIV
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Problems solved by technology
[0005] At present, the main products of citronella oil are citronella essential oil and citronella hydrosol. The solubility of citronella hydrosol is poor, citronella essential oil is volatile, and the physical properties of the product are unstable, difficult to preserve, difficult to disperse in water, and low utilization.
Method used
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Embodiment 1
[0060] Embodiment 1 preparation liquid concentration is the citronella oil nanoemulsion of 0.01%
[0061]
[0062] The specific operation steps are:
[0063] 1) first citronella oil is completely dissolved in co-surfactant;
[0064] 2) add surfactant and mix well, set aside;
[0065] 3) Slowly add distilled water dropwise to the solution prepared in step 2), and keep stirring while adding dropwise, until a uniform and transparent system is formed.
Embodiment 2
[0066] Embodiment 2 preparation liquid concentration is the citronella oil nanoemulsion of 0.4%
[0067]
Embodiment 3
[0068] Embodiment 3 preparation liquid concentration is the citronella oil nanoemulsion of 0.5%
[0069]
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Abstract
The invention discloses oil in water type citionella oil nanoemulsion. The grain diameters of the nanoemulsion range from 1nm to 100nm. The nanoemulsion comprises 0.01%-17.6% of citionella oil, 23-44% of surface active agent, 6.4-16.5% of cosurfactant, 0-10% of oil phase and the balance of distilled water, wherein the sum of the mass percent of the raw materials is 100%. The citionella oil nanoemulsion has the functions of analgesia, antiphlogosis, antibiosis, mosquito expelling, parasite expelling, emotion regulating and the like, has the characteristics of being low in viscosity, good in stability, high in dispersibility, quick in absorption and the like, and is high in availability. The invention is simple in preparation technology, low in energy consumption, small in toxicity, high in safety and large-scale in production without special equipment.
Description
technical field [0001] The invention belongs to the fields of medicine and daily chemical industry, and relates to a new dosage form of citronella oil with the functions of analgesia, mosquito repellent, anti-inflammatory, antibacterial and emotion regulation, in particular to an oil-in-water type citronella oil nanoemulsion and its preparation method. Background technique [0002] Lemongrass is a perennial herb, mainly produced in India and Sri Lanka, all over tropical Asia, and cultivated in southern provinces of my country. Pungent in taste, warm in nature, with a strong lemon fragrance, has the effect of dispelling cold and dampness, relieving cough and relieving asthma. It has been commercially applied since this century, mainly for medical treatment, health care and food therapy. Citronella oil purifies and uplifts the mood, relieving depressed moods. The warm herbal flavor fills people with a simple and natural fragrance environment, which can make people feel happ...
Claims
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IPC IPC(8): A61K36/899A61K9/107A61K8/97A61K47/34A61Q17/02A01N65/44A01P3/00A01P17/00A61P11/06A61P11/14
CPCY02A50/30
Inventor 欧阳五庆王璟李雅
Owner NORTHWEST A & F UNIV