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Traditional Chinese medicine formula with kidney tonifying and clearing for treating chronic hepatitis b (including chronic hepatitis B virus carriers)

A technology for chronic hepatitis B and chronic hepatitis B, applied in drug combinations, antiviral agents, pharmaceutical formulations, etc., can solve problems such as poor efficacy in virus carriers, and achieve the effects of preventing and controlling disease progression and inhibiting replication.

Inactive Publication Date: 2013-08-21
SHENZHEN TRADITIONAL CHINESE MEDICINE HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] In short, my country is a high-incidence area of ​​HBV. The current hepatitis B vaccine program immunization, the proportion of adults with chronic HBV infection is gradually increasing; high viral load and ALT baseline level, age over 30 years old are independent risks of liver cirrhosis and liver cancer in hepatitis B carriers Factors, the current modern medical antiviral treatment has poor curative effect on chronic hepatitis B and chronic hepatitis B virus carriers, and traditional Chinese medicine has accumulated certain advantages in long-term clinical practice

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] A kidney-tonifying and clearing traditional Chinese medicine formula for treating chronic hepatitis B (including chronic hepatitis B virus carriers), the weight content of which is composed of:

[0019] Indian Phyllostachys 10g, Dodder 5g, Lingpi 20g, Ligustrum lucidum 10g, Eclipta 10g, Bupleurum 5g, Paeoniae Alba 5g, Citrus aurantium 5g, Peach kernel 5g, Licorice 3 g, Polygonum cuspidatum 10g.

Embodiment 2

[0021] A kidney-tonifying and clearing traditional Chinese medicine formula for treating chronic hepatitis B (including chronic hepatitis B virus carriers), the weight content of which is composed of:

[0022] Indian Phyllostachys 20g, Dodder 15g, Lingpi 40g, Ligustrum lucidum 15g, Eclipta 15g, Bupleurum 10g, Paeoniae Alba 10g, Citrus aurantium 15g, peach kernel 15g, licorice 8g, Polygonum cuspidatum 20g.

Embodiment 3

[0024] A kidney-tonifying and clearing traditional Chinese medicine formula for treating chronic hepatitis B (including chronic hepatitis B virus carriers), the weight content of which is composed of:

[0025] Indian Phyllostachys 50g, Cuscuta 30g, Lingpi 50g, Ligustrum lucidum 20g, Eclipta 20g, Bupleurum 15g, Paeoniae Alba 30g, Citrus aurantium 10g, peach kernel 30g, licorice 10g, Polygonum cuspidatum 15g.

[0026] Case selection: 300 cases of chronic hepatitis B patients aged 7-65 years old were selected, and a treatment group and a control group were set up; the interactive language response system IVRS was used for randomized management.

[0027] Dosage and usage of the Chinese medicine composition: 1 packet per day, divided into 2 doses, course of treatment: 48 weeks.

[0028]Main efficacy indicators: (1) Serum HBV-DNA was detected at 12, 24, 36, and 48 weeks after taking the drug, and the method was COBAS method; (2) Serum hepatitis B virus markers (HBsAg, HBsAg, HBeAg)...

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Abstract

The invention relates to a traditional Chinese medicine formula with kidney tonifying and clearing for treating chronic hepatitis b (including chronic hepatitis B virus carriers), in particular to a formula with kidney tonifying and clearing combining clearing, expelling, activating, and tonifying, comprising the following ingredients: 10-50 g of India Phyllanthus urinaria, 5-30 g of semen cuscutae, 10-50 g of epimedium herb, 10-30 g of glossy privet fruit, 10-30 g of eclipta alba, 5-20 g of radix bupleuri, 5-30 g of white peony root, 5-20 g of immature bitter orange, 5-30 g of peach seed, 3-15 g of licorice, and 10-30 g of giant knot weed. The traditional Chinese medicine formula has the effects of clearing heat and detoxifying, kidney tonifying and eliminating pathogens, and quickening blood and dispelling stasis, can effectively resist the replication of hepatitis b virus (HBV-DNA), reduce the expression of hepatitis b virus serum markers (HBsAg, HBeAg); and by regulating organism immunity function and regulating the state of immunologic tolerance, the traditional Chinese medicine formula effectively controls the progress of chronic hepatitis b (including chronic hepatitis B virus carriers).

Description

technical field [0001] The invention relates to a kidney-tonifying and clearing traditional Chinese medicine formula for treating chronic hepatitis B (including chronic hepatitis B virus carriers), in particular to a formula for treating chronic hepatitis B (including chronic hepatitis B virus Carrier) kidney-tonifying and clearing traditional Chinese medicine formula, which belongs to the technical field of traditional Chinese medicine. Background technique [0002] Chronic hepatitis B is currently a clinically intractable disease that can gradually evolve into liver cirrhosis, liver cancer, and end-stage liver disease as the disease progresses. Chronic hepatitis B belongs to the categories of "liver pain", "hypochondriac pain" and "accumulation" in the traditional medicine of the motherland. Its disease location is mainly in the liver, spleen and kidney. , its treatment is mostly based on clearing heat and detoxifying, removing dampness and removing blood stasis, soothing...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/75A61P1/16A61P31/20
Inventor 童光东周大乔
Owner SHENZHEN TRADITIONAL CHINESE MEDICINE HOSPITAL