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Normal-temperature preparation method of codonopsis pilosula submicron powder

A technology of powdered Codonopsis pilosula and room temperature, which is applied in powder delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of restricting the large-scale production of veterinary traditional Chinese medicine ultrafine powder, low bioavailability, and poor fluidity. , to achieve the effect of being suitable for large-scale industrial production, improving the rate of cell wall breaking, and enhancing pharmacological effects

Active Publication Date: 2013-12-04
HENAN KANGXING PHARMA +1
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  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

[0003] At present, the Codonopsis ginseng additives used in livestock and poultry are all coarse powder powders, which have problems such as large dosage, coarse dosage form, poor appearance, insufficient release of active ingredients, and low bioavailability, which seriously affect the quality of traditional Chinese medicine and clinical health effects.
[0004] Traditional Chinese medicine ultrafine pulverization technology is an update and development of traditional pulverization technology. It not only retains the advantages of traditional Chinese medicine preparation technology, but also injects new vitality into the modern production of Chinese medicine. It has broad application prospects, but there are still some problems in actual production. Problems and problems: (1) Low production efficiency and high energy consumption are the main factors restricting the large-scale production of veterinary traditional Chinese medicine ultrafine powder
In the traditional closed-circuit crushing process, when most of the materials have reached the fineness requirements, there is always a small part of coarse powder mixed in it. To further crush this part of coarse powder to the required particle size, it is necessary to greatly prolong the crushing time, so that the crushing The efficiency is reduced and the energy consumption is greatly increased; (2) There is a difference in particle size uniformity of the material after classification in winnowing classification and classification wheel classification, which greatly affects the production quality of Chinese veterinary compound superfine powder, especially when it is used in animal drinking water or granules When the material is used, it is difficult to meet the requirements due to the existence of a large number of unbroken cells
(3) In the traditional unidirectional airflow screening, when Chinese medicine is ultrafinely pulverized, as the particle size decreases, the surface area and surface energy of the material particles increase, the adsorption increases, the fluidity becomes poor, and it is easy to aggregate into large particles It is difficult to sieve and classify powders with a fineness of more than 200 mesh

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Embodiment Construction

[0031] Such as figure 1 , 2 Shown, superfine powder Codonopsis pilosula normal temperature preparation method of the present invention, comprises the following steps:

[0032] The first step is to take the traditional Chinese medicine Codonopsis pilosula, wash it, dry it, and dry it naturally or until the moisture content is ≤10%;

[0033] The second step is to pulverize Codonopsis pilosula at 20°C to 25°C to obtain a coarse powder with a particle size of 60-80 mesh;

[0034] The third step, at first turn on the powder conveying fan 15, the induced draft fan 5, the blower 11, and the drive motor 8. The blowing pressure of the powder conveying fan 15 is 24kpa, and the blowing volume is 150m 3 / h; the induced air pressure of the induced draft fan 5 is 1000pa, and the induced air volume is 3000m 3 / h; the blast pressure of blower 11 is 33kpa, and the blast volume is 320m 3 / h; the rotational speed of the drive motor 8 is 155 rpm.

[0035] 1. After the coarse powder obtaine...

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Abstract

The invention discloses a normal-temperature preparation method of codonopsis pilosula submicron powder, which comprises: completely washing codonopsis pilosula which is a Chinese medicine, and airing till the water content is less than or equal to 10 percent; grinding codonopsis pilosula into coarse powder at normal temperature; grinding the coarse powder, delivering the powder to a special bidirectional airflow sieving machine to sieve the powder with a 500-mesh sieve, delivering the undersize submicron powder with a particle size of less than or equal to 25 micrometers to a cyclonic material collection device by an air flow generated by a draft fan and collecting finished codonopsis pilosula submicron powder; and collecting oversize powder with a funnel and delivering the powder by a pipe to a rod mill for secondary circular grinding. The method has the advantages that: the whole preparation process is carried out at normal temperature, and the need of low temperature or special additional conditions is obviated; the particle size of the prepared finished codonopsis pilosula submicron powder is less than or equal to 25 micrometers, and the cell wall breakage rate and bioavailability are increased greatly; and the bidirectional airflow sieving machine used by the method greatly simplifies the preparation process of codonopsis pilosula submicron powder, makes the quality standard of Chinese powder controllable and allows large-scale industrial production to be carried out.

Description

technical field [0001] The invention relates to veterinary drug additives, in particular to a normal-temperature preparation method of ultrafine powder Codonopsis pilosula; the invention also relates to a special two-way airflow screening machine used in the method. Background technique [0002] In recent years, the probability of livestock and poultry infection has been increasing, and the amount of antibiotics has also increased significantly. Food safety accidents have occurred frequently, which has aroused people's great attention to food safety issues. Green and residue-free are people's requirements for animal products. The core, so people put the goal back to the traditional Chinese medicine in our country, using Chinese medicine as a feed additive to improve the immunity of livestock and poultry, and promote growth and development. Codonopsis Codonopsis was first recorded in "Materia Medica Congxin", and it is the dried root of Platycodonaceae plants, Suhua Codonops...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/344A61K9/14B02C23/20A23K1/16A61P1/14
Inventor 马霞张国祖孔维丽杨明峰郭艳丽
Owner HENAN KANGXING PHARMA
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