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Traditional Chinese herbal composition for treating allergic purpura as well as preparation method and application thereof

A technology for allergic purpura and composition, which is applied in the directions of drug combination, allergic diseases, medical formula, etc., can solve problems such as unsatisfactory curative effect and partial prescription thinking.

Active Publication Date: 2014-08-20
GUANGXI NANNING BAIHUI PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the treatment of allergic purpura in traditional Chinese medicine is generally aimed at different types of syndrome differentiation. not satisfactory

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] Prescription: 800g of spatholobus, 400g of Eclipta prostrata, 400g of motherwort, 240g of comfrey, 240g of duckweed, 240g of white fresh peel, 240g of mulberry, 160g of nepeta.

[0056] Preparation method: Take the above eight medicinal materials, add water and extract 3 times. The amount of water added is 10, 8, and 8 times, and the extraction time is 2, 1, 1 hour. Filter, combine the filtrate and concentrate under reduced pressure to 60℃. The extract with a density of 1.32 to 1.35 is dried under reduced pressure, pulverized into fine powder, added with appropriate amount of sodium carboxymethyl starch, microcrystalline cellulose and magnesium stearate, and compressed into tablets to obtain.

Embodiment 2

[0058] Prescription: 700g of spatholobi, 300g of Eclipta prostrata, 300g of motherwort, 200g of comfrey, 200g of duckweed, 200g of white fresh peel, 200g of mulberry, 120g of nepeta.

[0059] Preparation method: the spatholobi and white fresh bark were heated and refluxed with 90% ethanol for 3 times, the amount of solvent added was 7, 5, and 5 times, and the extraction time was 3, 2, and 1 hours; filtered, combined the filtrate, and recovered Ethanol, an extract with a relative density of 1.20~1.30 when the solution is concentrated to 60℃, ready for use; the dregs are mixed with mulberry bark, nepeta, comfrey, motherwort, duckweed and Eclipta prostrata, add water to extract twice, add water The amount is 10, 8 times, and the extraction time is 2, 1.5 hours. Filter, combine the filtrate, and concentrate the extract with a relative density of 1.32 to 1.35 at 60°C. Mix with the above alcohol extract, dry, and crush into fine particles. Powder, add appropriate amount of sodium carbo...

Embodiment 3

[0061] Prescription: Spatholobus spatholobi 600g, Eclipta prostrata 200g, Motherwort 200g, Lithospermum 200g, Duckweed 200g, White fresh peel 200g, Mulberry 200g, Nepeta 200g.

[0062] Preparation method: the above eight flavors, Caulis spatholobi and white fresh peels were heated and refluxed with 70% ethanol for 3 times, the amount of solvent added was 7, 7, and 5 times, and the extraction time was 2, 1.5, and 1 hour; filtered, Combine the filtrates, recover ethanol, and concentrate the solution to an extract with a relative density of 1.31~1.35 at 60°C for use; mix the medicine residue with mulberry bark, nepeta, comfrey, motherwort, duckweed and Eclipta prostrata, and add water to extract 2 The amount of water added is 10, 8 times, and the extraction time is 3, 1.5 hours; filtered, combined the filtrate, and concentrated to an extract with a relative density of 1.31 to 1.35 at 60°C, mixed with the above alcohol extract, and dried , Crushed into fine powder, granulated with et...

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PUM

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Abstract

The invention provides a traditional Chinese herbal composition for treating allergic purpura and a method for preparing the same. The traditional Chinese herbal composition is prepared from 8 active pharmaceutical ingredients of suberect spatholobus stem, eclipta alba, leonurus, lithospermum, common ducksmeat herb, cortex dictamni, mulberry bark and schizonepeta according to a certain weight ratio. The traditional Chinese herbal composition has a good curative effect on allergic purpura.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine composition for treating allergic purpura, and a preparation method and application thereof. Background technique [0002] Henoch-Schonlein Syndrome (HSP), also known as Hen-Schuh Syndrome (HSP), is a more common microvascular allergic bleeding disease. Due to the body's allergic reaction to certain allergenic substances, capillary fragility and permeability increase , Blood extravasation, causing bleeding in the skin, mucous membranes and certain organs. It may be accompanied by other allergic manifestations such as angioedema and urticaria. There are many reasons for allergic purpura, which are generally considered to be related to factors such as bacterial and viral infections, parasitic infections, animal protein intake, and drug use. The pathogenesis is that specific physique is affected by the above factors, leading to immunity Dysfunction, the formation of immune complexes and deposits on the ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/88A61P37/08A61P7/04
Inventor 张加余李西秦
Owner GUANGXI NANNING BAIHUI PHARMA GRP