Method for producing fluorine-containing ether with high purity
A manufacturing method and technology of fluorine-containing ethers, which are applied in the field of manufacture of fluorine-containing ethers, and can solve problems such as inability to separate fluorine-containing alkyl alcohols and increase in the number of processes
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[0078] Next, the present invention will be described based on examples and comparative examples, but the present invention is not limited to the examples.
[0079] In addition, the measuring method used in this invention is as follows.
[0080] (1) Composition analysis
[0081] NMR method: AC-300 manufactured by BRUKER was used.
[0082] 19 F-NMR:
[0083] Measuring conditions: 282MHz (trichlorofluoromethane = 0ppm)
[0084] 1 H-NMR:
[0085] Measuring conditions: 300MHz (tetramethylsilane = 0ppm)
[0086] (2) Concentration (GC%) analysis
[0087] Gel chromatography (GC) method: GC-17A manufactured by Shimadzu Corporation was used. Column: DB624 (Length 60, I.D 0.32, Film 1.8 μm). Determination limit: 0.001%
[0088] (3) Moisture content (mass % or ppm)
[0089] Karl Fischer method: MKC-501 manufactured by Kyoto Denshi Kogyo Co., Ltd. was used. Catholyte: Aquamicron CXU manufactured by Mitsubishi Chemical Co., Ltd. Anolyte: Aquamicron AKX manufactured by Mitsubishi...
Synthetic example 1
[0090] Synthesis Example 1 (Manufacture of Fluorinated Ether Crude Liquid)
[0091] The inside of the 6L autoclave made of stainless steel was vacuumed, and 401 g of potassium hydroxide (7.15 mol. The ratio to 1 mole of fluorine-containing alkyl alcohol was 0.55 mole), water (1604 mL), and fluorine-containing 2,2,3,3-tetrafluoro-1-propanol (boiling point: 109°C, specific gravity: 1.4) of alkyl alcohol: HCF 2 CF 2 CH2 OH (1716 g, 13 mol), followed by 20 vacuum-nitrogen displacements at room temperature. After vacuuming the inside of the system, tetrafluoroethylene was filled so that the pressure was 0.1 MPa, and heating was performed so that the inside of the reaction system was 85°C. After the internal temperature reached 85° C., tetrafluoroethylene was added little by little to keep the reaction pressure at 0.5 MPa to 0.8 MPa. Adjust the internal temperature of the system to keep it at 75°C to 95°C.
[0092] When the amount of tetrafluoroethylene added reached 0.5 mole re...
Synthetic example 2
[0095] A fluorine-containing ether was synthesized in the same manner as in Synthesis Example 1 except that the added amount of tetrafluoroethylene was changed to 780 g (7.8 mol). Table 1 shows the composition of the obtained fluorine-containing ether production liquid.
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