Drug for recuperating immunity of organisms after fire burn and preparation method thereof

Abstract

The invention discloses a drug for recuperating immunity of organisms after fire burn and a preparation method of the drug. The drug comprises the following compositions in parts by weight: 10-50 parts of astragalus mongholicus, 10-50 parts of honeysuckle, 10-30 parts of radix scutellariae, 5-20 parts of radix ophiopogonis and 5-20 parts of rheum officinale. The preparation method comprises the following steps of: weighing each raw material in proportion, and crushing half of the raw materials and sieving through an 80-120-mesh sieve; boiling the other half of the raw materials with water for twice, combing the decoction, filtering and then concentrating the decoction to a relative density of 1.20-1.25, wherein the volume of the added water is 3-5 times to the volume of the raw materials, and the boiling time is 30-60 minutes at each time; and evenly mixing the fine powders and the concentrated solution, drying the mixture to fine powders, sieving through the 80-120-mesh sieve, and preparing water-bindered pills. The drug disclosed by the invention has obvious dual-direction regulating effects on humoral immunity and cellular immunity functions of burned patients. The drug can effectively restrain the expression of early inflammatory mediators in a burn inflammatory reaction and increase anti-inflammatory mediators, and meanwhile, the drug is particularly suitable for treatment of burns in basic-level hospitals in China because of the advantages of wide medicinal herbs resource, low cost, little toxic and side effects and the like of traditional Chinese medicines.

Description

technical field [0001] The invention relates to a medicine for regulating the immune function of a burned body and a preparation method thereof. Background technique [0002] Immunological dysfunction after burns is one of the important causes of infection and multiple system organ dysfunction syndrome. After the human body is burned, the body's cellular immunity and humoral immunity are reduced to varying degrees, which reduces the body's resistance to foreign invasion and infection; the ability of serum regulation decreases, and the phagocytosis and bactericidal power of neutrophils decrease, which promotes sepsis. occurrence of the disease. The degree of dysfunction of the entire immune system in patients with extremely severe burns is more obvious, and the performance of immune imbalance is more typical. Aiming at this disordered state, a variety of immunotherapy programs have been proposed and researched, such as endotoxin and exotoxin antibody neutralizing toxin ther...

AI Technical Summary

Problems solved by technology

Aiming at this disordered state, a variety of immunotherapy programs have been proposed and researched, such as endotoxin and exotoxin antibody neutralizing toxin therapy, antagonism therapy of inflammatory mediators such as cytokines, non-steroid drug therapy, immunoregulatory hormone therapy, immune Nutrient adjustment therapy, thymus-mimetic drug therapy, and nuclear transcription factor inhibitory therapy have achieved certain curative effects, but because some have single effects, some have unstable curative effects, some have large toxic and side effects, and are expensive, it is difficult to use clinical application promotion