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Composition for improving sleep and preparation method and application thereof

A technology for improving sleep and composition, which is applied in the field of composition for improving sleep, can solve the problems of cumbersome preparation process and large amount of prescription, and achieve the effects of reasonable process, mild drug properties and no adverse reactions

Active Publication Date: 2013-02-27
吉林一正药业集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above composition has a large amount of prescription, and the preparation process is loaded down with trivial details

Method used

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  • Composition for improving sleep and preparation method and application thereof
  • Composition for improving sleep and preparation method and application thereof
  • Composition for improving sleep and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Embodiment 1: Capsules

[0052] 1. Composition:

[0053] Poria cocos 550g, jujube seed 500g, lily 400g, ginseng 170g, schisandra 120g.

[0054] 2. Preparation method:

[0055] 1) Purify each raw material separately and pass the inspection; take 100g of ginseng, dry it at 60°C, crush it, pass it through a 100-mesh sieve into a fine powder, sterilize it with cobalt 60, and set it aside;

[0056] 2) Take the remaining ginseng (70g) from step 1) and the jujube seed and schisandra of the above weight and extract twice with 70% ethanol under reflux. After 1.5 hours, filter (preserve the dregs), combine the filtrate, recover the ethanol from the filtrate and concentrate it to a clear paste with a relative density of 1.30~1.35 (measured at 60°C), and set aside;

[0057] 3) Take the above-mentioned weight of Poria cocos, lily and alcohol-extracted medicinal residues in step 2), add water to decoct 2 times, each time add 8 times the amount of water of the raw materials of Pori...

Embodiment 2

[0060] Embodiment 2: tablet

[0061] 1. Composition:

[0062] Poria cocos 530g, jujube seed 520g, lily 380g, ginseng 190g, schisandra 100g.

[0063] 2. Preparation method:

[0064] 1) Purify each raw material separately and pass the inspection; take 95g of ginseng, dry it at 50°C, crush it, pass it through a 90-mesh sieve into a fine powder, sterilize it with cobalt 60, and set it aside;

[0065] 2) Take the remaining ginseng (95g) from step 1) and the jujube kernels and schisandra of the above weight and reflux extract them with 75% ethanol for 3 times, add 7 times the amount of ethanol each time to extract 1 hours, filter (preserve the dregs), combine the filtrate, recover the ethanol from the filtrate and concentrate it to a clear paste with a relative density of 1.30~1.35 (measured at 60°C), and set aside;

[0066] 3) Take the above-mentioned weight of Poria cocos, lily and alcohol-extracted medicinal residues in step 2) and add water to decoct 4 times, each time add 7 ...

Embodiment 3

[0069] Embodiment 3: Granules

[0070] 1. Composition:

[0071] Poria cocos 570g, jujube seed 480g, lily 420g, ginseng 150g, schisandra 140g.

[0072] 2. Preparation method:

[0073] 1) Purify each raw material separately and pass the inspection; take 97.5g of ginseng, dry it at 55°C, crush it, pass it through a 110-mesh sieve into a fine powder, sterilize it with cobalt 60, and set it aside;

[0074] 2) Take the remaining ginseng (52.5g) from step 1) and the jujube kernels and schisandra of the above weight and reflux extraction with 65% ethanol for 4 times. After 2 hours, filter (preserve the dregs), combine the filtrate, recover the ethanol from the filtrate and concentrate it to a clear paste with a relative density of 1.30~1.35 (measured at 60°C), and set aside;

[0075] 3) Take the above-mentioned weight of Poria cocos, lily and alcohol-extracted medicinal residues in step 2) and add water to decoct 3 times, each time add 6 times the amount of water of the sum of raw ...

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Abstract

The invention relates to a composition for improving sleep and a preparation method and application thereof. The composition comprises the following components in parts by weight: 400 to 700 parts of tuckahoe, 350 to 650 parts of seed of wild jujube, 250 to 550 parts of lily, 100 to 250 parts of ginseng and 40 to 200 parts of schisandra. The five gouts of Chinese medicament raw materials are reasonably matched, and the raw materials achieve a good synergistic effect according to the given component proportion, namely each Chinese medicament exerts the effect; the composition has a remarkable effect on the aspect of improving the sleep and is superior to the prior art, namely the formula is optimal, the process is reasonable, the active ingredients are extracted completely, and the treatment effect of the composition is well exerted; the composition does not have adverse response and is high in safety; and the equipment is simple, the cost is low, and industrialized production can be realized.

Description

technical field [0001] The invention relates to the field of pharmaceutical or health product compositions, in particular to a composition for improving sleep, its preparation method and application. Background technique [0002] Sleep disturbance refers to the manifestation of abnormal sleep volume and abnormal behavior during sleep, which is a manifestation of the disturbance of the normal rhythmic alternation of sleep and wakefulness. It can be caused by a variety of factors and is often associated with physical illness, including sleep disorders and parasomnias. Sleep is closely related to people's health. Long-term insomnia will lead to brain dysfunction, cause various harms to the body, and seriously affect physical and mental health. According to the survey, many people suffer from sleep disorders or sleep-related diseases, and the proportion of adults with sleep disorders is as high as 30%. Experts point out that sleep is an extremely important physiological functi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8967A61P25/20A23L1/29A23L33/00
Inventor 于春江
Owner 吉林一正药业集团有限公司
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