Synthesis method of 2-acrylamide-2-methylpropanesulfonic acid (AMPS)
A technology of acrylamide and methylpropanesulfonic acid, applied in the preparation of sulfonic acid, organic chemistry, etc., can solve the problems of low purity of AMPS, achieve high yield, and suppress the production of sulfonated by-products
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Embodiment 1
[0030] This example is used to illustrate the synthesis method of 2-acrylamido-2-methylpropanesulfonic acid provided by the present invention.
[0031] (1) In a four-neck flask equipped with a temperature control device, a stirrer, a thermometer and a gas feed device, add 330 g of acrylonitrile, cool the acrylonitrile to -10° C. and add 63 g of sulfuric acid with a concentration of 97% by weight. Then at this temperature, 10.7 g of acetic anhydride was added, the temperature was maintained at -10° C. during and after the addition and stirring was continued for 1 hour.
[0032](2) After raising the temperature to 40° C., 35 g of isobutylene was introduced to carry out the reaction.
[0033] (3) After the introduction of isobutylene is completed, the reaction is terminated after 1 hour of heat preservation. The reaction solution was vacuum filtered to obtain a filter cake and a filtrate. The filter cake was vacuum-dried at a drying temperature of 60° C. and a pressure of 10 KP...
Embodiment 2
[0036] This example is used to illustrate the synthesis method of 2-acrylamido-2-methylpropanesulfonic acid provided by the present invention.
[0037] (1) In a four-neck flask equipped with a temperature control device, a stirrer, a thermometer and a gas feed device, add 330 g of acrylonitrile, cool the acrylonitrile to -10° C. and add 63 g of sulfuric acid with a concentration of 95% by weight. Then at this temperature, add 9.1g P 2 o 5 , the temperature was maintained at -10°C during and after the addition and stirring was continued for 1 hour.
[0038] (2) After raising the temperature to 40° C., 35 g of isobutylene was introduced to carry out the reaction.
[0039] (3) After the introduction of isobutylene is completed, the reaction is terminated after 1 hour of heat preservation. The reaction solution was vacuum filtered to obtain a filter cake and a filtrate. The filter cake was vacuum-dried at a drying temperature of 60° C. and a pressure of 10 KPa to obtain a drie...
Embodiment 3
[0042] This example is used to illustrate the synthesis method of 2-acrylamido-2-methylpropanesulfonic acid provided by the present invention.
[0043] (1) In a four-neck flask equipped with a temperature control device, a stirrer, a thermometer and a gas feed device, add 330 g of acrylonitrile, cool the acrylonitrile to -10° C. and add 63 g of sulfuric acid with a concentration of 99% by weight. Then at this temperature, 5.5 g of propionic anhydride were added, the temperature was maintained at -10° C. during and after the addition and stirring was continued for 1 hour.
[0044] (2) After raising the temperature to 40° C., 35 g of isobutylene was introduced to carry out the reaction.
[0045] (3) After the introduction of isobutylene is completed, the reaction is terminated after 1 hour of heat preservation. The reaction solution was vacuum filtered to obtain a filter cake and a filtrate. The filter cake was vacuum-dried at a drying temperature of 60° C. and a pressure of 1...
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