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Microcapsule preparation for normalizing stomach and tonifying spleen

A technology of microcapsules and preparations, applied in the field of pharmaceutical compositions and preparations thereof, can solve problems such as unfavorable external development of traditional Chinese medicine preparations, single dosage form, unfavorable medication safety for pediatric patients and the like

Active Publication Date: 2014-06-25
CP PHARMA QINGDAO CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the commonly used prescriptions for the treatment of children's anorexia mostly include Uncaria and cicada slough. side effects, which is also detrimental to the safety of the drug in pediatric patients
And in the prior art, dosage forms such as oral liquid and syrup are mostly used, and the dosage form is relatively single, which is not conducive to the external development of traditional Chinese medicine preparations

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0010] Magnolia bark 600g, chrysanthemum 600g, citrus aurantium 800g, coix seed 800g, rice bud 800g, hawthorn 400g, bamboo leaf 600g, licorice 1000g, sucrose powder 800g, monoglyceride 2g, sucrose ester 0.5g, maltodextrin 30g, soybean protein 60g.

[0011] The preparation method is as follows: 1) Weigh Magnolia officinalis officinalis officinale, chrysanthemum, Citrus aurantium, coix seed, hawthorn, rice bud, light bamboo leaf and licorice in parts by weight, soak, add 4 times of water and decoct 3 times, each time for 45 minutes, Combine the decoction liquid, concentrate, add 70% ethanol to stand still, filter, remove ethanol by rotary evaporation, and dry to obtain powder; 2) Weigh sucrose powder by weight and mix it with the powder obtained in 1); 3) Take 10g of the powder obtained by mixing Add it to 50ml of 70% ethanol as the capsule core for later use; 4) Weigh monoglycerides, sucrose esters, maltodextrin, and soybean protein by weight and dissolve them in 700ml of water...

Embodiment 2

[0013] Magnolia bark 700g, chrysanthemum 700g, citrus aurantium 900g, coix seed 900g, rice bud 900g, hawthorn 500g, bamboo leaf 700g, licorice 1100g, sucrose powder 900g, monoglyceride 4g, sucrose ester 0.7g, maltodextrin 45g, soybean protein 60g.

[0014] The preparation method is as follows: 1) Weigh Magnolia officinalis officinalis officinale, chrysanthemum, Citrus aurantium, coix seed, hawthorn, rice bud, light bamboo leaf and licorice in parts by weight, soak, add 5 times of water and decoct 3 times, each time for 45 minutes, Combine the decoction liquid, concentrate, add 70% ethanol to stand still, filter, remove ethanol by rotary evaporation, and dry to obtain powder; 2) Weigh sucrose powder by weight and mix it with the powder obtained in 1); 3) Take 10g of the powder obtained by mixing Add it to 50ml of 70% ethanol as the capsule core for later use; 4) Weigh monoglycerides, sucrose esters, maltodextrin, and soybean protein by weight and dissolve them in 700ml of water...

Embodiment 3

[0016] Magnolia bark 650g, chrysanthemum 650g, citrus aurantium 850g, coix seed 850g, rice bud 850g, hawthorn 450g, bamboo leaf 650g, licorice 1050g, sucrose powder 850g, monoglyceride 3g, sucrose ester 0.6g, maltodextrin 30g, soybean protein 45g.

[0017] The preparation method is as follows: 1) Weigh Magnolia officinalis officinalis officinale, chrysanthemum, Citrus aurantium, coix seed, hawthorn, rice bud, light bamboo leaf and licorice in parts by weight, soak, add 5 times of water and decoct 3 times, each time for 45 minutes, Combine the decoction liquid, concentrate, add 70% ethanol to stand still, filter, remove ethanol by rotary evaporation, and dry to obtain powder; 2) Weigh sucrose powder by weight and mix it with the powder obtained in 1); 3) Take 10g of the powder obtained by mixing Add it to 50ml of 70% ethanol as the capsule core for later use; 4) Weigh monoglycerides, sucrose esters, maltodextrin, and soybean protein by weight and dissolve them in 700ml of water...

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PUM

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Abstract

The invention provides a microcapsule preparation for treating splenic and gastric incoordination and anorexia. The medicine comprises officinal magnolia bark, chrysanthemum, fructus aurantii, semen coicis, fructus oryzae germinatus, hawthorn, lophatherum gracile, liquorice and sucrose powder; and a wall material comprises glycerol monostearate, sucrose ester, maltodextrin and soy protein.

Description

technical field [0001] The invention relates to a pharmaceutical composition and a preparation method thereof, in particular to a Hewei Jianpi microcapsule preparation for treating anorexia and a preparation method thereof. Background technique [0002] Anorexia is the name of the disease in modern medicine, and its main clinical manifestations are loss of appetite and reduced food intake for a long time. Weak spleen and stomach, disharmony between spleen and stomach can cause anorexia, and the main clinical manifestations are loss of appetite and reduced food intake for a long time. According to the clinical manifestations of anorexia, Sang Li et al. divided them into six types: 1. Spleen dysfunction and movement type, which should be treated by invigorating the spleen to help transport, appetizing and increasing food; , 3. Liver Qi stagnation type, treatment should soothe liver and regulate qi, transport spleen and appetizer, 4. Food stagnation internal resistance type, t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8994A61K47/42A61K9/50A61P1/14
Inventor 王明刚任莉陈阳生
Owner CP PHARMA QINGDAO CO LTD
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