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Apparatus and method for manufacturing solid beads

A kind of equipment and bead technology, which is applied in the direction of liquid separation into beads and granulation, vibrating device granulation, etc. It can solve the problem that it is difficult to produce large-volume particles.

Active Publication Date: 2017-04-26
MIDATECH PHARMA WALES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, it is difficult to generate large volume particles using this equipment

Method used

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  • Apparatus and method for manufacturing solid beads
  • Apparatus and method for manufacturing solid beads
  • Apparatus and method for manufacturing solid beads

Examples

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Embodiment Construction

[0099] figure 1 Apparatus for use in the method of the invention is shown. figure 1 A cross-section of the device is shown, along with a rear-end view of part of the device. The device is denoted by reference numeral 1 and comprises a flow channel 2 and a piezoelectric droplet generator 3 (Microdrop Technologies GmbH, Norderstedt, Germany) distributed at a distance from the flow channel 2 . Said channel 2 is made of 316 stainless steel and has two parts: a first "open" part, generally indicated by reference numeral 6 , which is 6 mm deep and 12 mm wide, and a second (closed) part 5 . A nozzle (not shown) is inserted in chamber 13 and a pump (not shown) delivers liquid 4 into flow channel 2 . The pump is a ring gear pump, but could be any pulseless flow device. The distance between the dispersion nozzle (not shown) of the piezoelectric droplet generator and the surface of the liquid 4 is 12 mm. The liquid in this example was tert-butanol (Sigma Aldrich, UK) at 15% by volume...

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Abstract

The present invention provides an apparatus for producing solid beads comprising at least one liquid droplet generator operable to produce droplets comprising a solute dissolved in a solvent, and at least one flowing a channel for carrying a second liquid, said at least one liquid droplet generator and said at least one flow channel being spaced relative to each other such that, in use, liquid droplets passing through a gas enter said fluid channel The second liquid, the solvent may dissolve into the second liquid, causing the solvent to break away from the droplets, thereby forming solid beads. The present invention also provides a method of manufacturing the solid beads.

Description

technical field [0001] The present invention relates to an apparatus and method for making solid beads and in particular, but not limitedly, to making small solid beads of relatively uniform size (typically having an average largest dimension of 20-200 microns). Background technique [0002] There are several known apparatuses for producing solid beads of relatively uniform size. For example, it is known to use microfluidic circuits in which a carrier fluid carried in a first microfluidic circuit impacts a carrier fluid carried in a second microfluidic circuit where the first and second microfluidic circuits meet. functional fluid. The droplets of the functional fluid are then frozen and desolvated. This setup provides good control of particle size and good size uniformity. However, it is difficult to generate large volumes of particles using such equipment. The device of the present invention seeks to solve this problem. Contents of the invention [0003] According t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B01J2/08B01J2/18
CPCB01J2/08B01J2/18B01J2/06
Inventor 丹尼尔·帕尔默欧文·沙迪克
Owner MIDATECH PHARMA WALES