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Medicinal composition containing staphylococcus albus and preparation method thereof

A technology of Staphylococcus albus and composition, which is applied in the directions of drug combination, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the problems of inconvenient taking, large dosage, poor taste and the like

Active Publication Date: 2013-11-27
JIANGSU SHENHUA PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are Staphylococcus albus tablets on the market, but the taste is poor when taken orally, the dosage is large, and it is inconvenient to take. It is not suitable for various groups of people such as the elderly and children.

Method used

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  • Medicinal composition containing staphylococcus albus and preparation method thereof
  • Medicinal composition containing staphylococcus albus and preparation method thereof
  • Medicinal composition containing staphylococcus albus and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] Ratio of Staphylococcus albus oral liquid: Staphylococcus albus powder 30%, Ganoderma lucidum powder (produced by Jiangsu Fufeng Biotechnology Co., Ltd.) 0.05%, Berberine hydrochloride 0.01%, Sorbitan fatty acid 3%, Chlorcresol 4%, Honey 2%, malic acid 0.04%, xanthan gum (Inner Mongolia Fufeng Biotechnology Co., Ltd.) 0.3%, add purified water to 100%, mix the above components and stir evenly.

[0065] Sterilization and filling of oral liquid: the mixed liquid with the above ratio is pasteurized at 100°C for 10 minutes, cooled, and filled into bottles.

[0066] In the Staphylococcus albus oral liquid prepared by the present embodiment, the wall-containing phosphate reaches 2.2% in terms of organic phosphorus, contains berberine in terms of berberine hydrochloride 6.0 mg / m3, and contains 4.3 mg / ml of total nitrogen; the oral liquid The shelf life is 2 years at room temperature, and the composition of the oral liquid is stable and uniform.

Embodiment 2

[0068] Ratio of Staphylococcus albus oral liquid: Staphylococcus albus powder 25%, Ganoderma lucidum powder 0.04%, Berberine hydrochloride 0.008%, Sorbitan fatty acid 4%, Chlorcresol 3%, Honey 3%, Malic acid 0.06%, Huang Raw gum 0.2%, add purified water to 100%, mix the above components and stir evenly.

[0069] Sterilization and filling of oral liquid: the mixed liquid with the above ratio is pasteurized at 100°C for 10 minutes, cooled, and filled into bottles.

[0070] In the Staphylococcus albus oral liquid prepared by the present embodiment, the wall-containing phosphoric acid is up to 2.1% in terms of organic phosphorus; the berberine is 5.8 mg / ml in terms of berberine hydrochloride, and the total nitrogen is 4.2 mg / ml; the oral liquid The shelf life is 2 years at room temperature, and the composition of the oral liquid is stable and uniform.

Embodiment 3

[0072] Preparation of Staphylococcus albus powder: centrifuge the above fermented liquid in a decanter (5000 rpm) to get the filtrate, dry at 40°C and pulverize.

[0073] Ratio of Staphylococcus albicans oral liquid: Staphylococcus albus powder 20%, Ganoderma lucidum powder 0.03%, Berberine hydrochloride 0.005%, Sorbitan fatty acid 2%, Chlorcresol 2%, Honey 1%, Malic acid 0.04%, Yellow Raw gum 0.1%, add purified water to 100%, mix the above components and stir evenly.

[0074] Sterilization and filling of oral liquid: the mixed liquid with the above ratio is pasteurized at 100°C for 10 minutes, cooled, and filled into bottles.

[0075] In the Staphylococcus albus oral liquid prepared by the present embodiment, the wall-containing phosphate reaches 2.0% in terms of organic phosphorus, contains berberine in terms of berberine hydrochloride 5.6 mg / ml, and contains 4.0 mg / ml of total nitrogen; the oral liquid The shelf life is 2 years at room temperature, and the composition of t...

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Abstract

The invention discloses a medicinal composition containing staphylococcus albus and a preparation method thereof. The medicinal composition is characterized by comprising the following active components in parts by weight: 20-30 parts of staphylococcus albus powder, 0.03-0.05 part of ganoderma lucidum bacterium powder, 0.005-0.01 part of berberine hydrochloride. The effects of alleviating cough and asthma and diminishing inflammation, achieved by taking the medicinal composition containing the staphylococcus albus, are more remarkable than those by taking staphylococcus albus singly, and the medicinal composition has the characteristics of high bioavailability, good stability and long preservation time, and is convenient to take.

Description

technical field [0001] The invention relates to a pharmaceutical composition containing staphylococcus albus and a preparation method thereof, belonging to the field of biotechnology. Background technique [0002] Cough is a common disease of respiratory system diseases. In general, cough is an important reflex protection mechanism. It is used to expel sputum or foreign objects in the respiratory tract through coughing, so as to keep the respiratory tract clean and unobstructed, thereby preventing the formation of infection. However, if the cough persists violently, not only the patient suffers, but also other complications are likely to occur. Therefore, it is necessary to choose an appropriate antitussive to relieve the cough. [0003] There are many reasons for coughing, mainly chemical and physical factors, which can be divided into two forms: endogenous and exogenous according to their properties. Endogenous cough is usually caused by excessive release of inflammatory ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/074A61P11/14A61P11/06A61K35/74A61K31/4375
Inventor 张芙蓉徐国华王英燕黄盟盟姚其胜
Owner JIANGSU SHENHUA PHARMA