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Application of Italy anchusa active part in preparation of antioxidant drugs, cosmetics and health care products

A technology of active parts and antioxidant effect, applied in the fields of health care products and cosmetics, plant extracts, and pharmaceuticals, can solve the problems of literature and patent reports that have not found the antioxidant effect of Italian oxtail

Active Publication Date: 2013-12-25
王琪
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Based on the existing literature, no literature or patent reports on the anti-oxidation effect of Buglossis and its constituents have been found

Method used

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  • Application of Italy anchusa active part in preparation of antioxidant drugs, cosmetics and health care products
  • Application of Italy anchusa active part in preparation of antioxidant drugs, cosmetics and health care products
  • Application of Italy anchusa active part in preparation of antioxidant drugs, cosmetics and health care products

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] 20g of dry powder of the whole plant of Buglossia italiana, at room temperature (10-30°C) cold-soaked in 200ml of 30% ethanol, ultrasonically extracted twice, each time for 10min (500W), the filtrates were taken and combined, and the solvent was recovered under reduced pressure to Dry, take an appropriate amount of the extract, prepare it into a 0.5mg / ml solution for later use, and measure its ability to scavenge DPPH free radicals and elastase inhibition, so as to compare with the activity of the active part of Buglossia italiana prepared later.

[0018] Results: The scavenging rate of DPPH free radical was 9% at the concentration of 50 μg / ml, and the inhibition rate of elastase was 2% at the concentration of 1 mg / ml.

Embodiment 2

[0020] 20g dry powder of the whole herb of Buglossia italiana, cold-soak in 200ml ethanol with a volume concentration of 60% at room temperature, and ultrasonically extract twice, each time for 30min (500W), combine the filtrates, recover the solvent under reduced pressure to dryness, and take an appropriate amount of extract , prepared into a 0.5mg / ml solution for later use, and its ability to scavenge DPPH free radicals was measured, so as to compare with the activity of the active part of the whole herb of Buglossia italiana prepared later.

[0021] Results: The scavenging rate of DPPH free radical was 14% at the concentration of 50μg / ml, and the inhibition rate of elastase was 4% at the concentration of 1mg / ml.

Embodiment 3

[0023] 20g dry powder of the whole herb of Buglossia italiana, cold-soak in 200ml ethanol with a volume concentration of 70% at room temperature, and ultrasonically extract twice, each time for 30min (500W), combine the filtrates, recover the solvent under reduced pressure until dry, and take an appropriate amount of extract , prepared into a 0.5mg / ml solution for later use, and its ability to scavenge DPPH free radicals was measured, so as to compare with the activity of the active part of the whole herb of Buglossia italiana prepared later.

[0024] Results: The scavenging rate of DPPH free radical was 25% at the concentration of 50 μg / ml, and the inhibition rate of elastase was 12% at the concentration of 1 mg / ml.

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Abstract

The invention relates to application of an Italy anchusa active part in the fields of drugs with antioxidation, cosmetics and health care products and discloses application of an Italy anchusa active part in preparation of antioxidant drugs, cosmetics and health care products. The preparation method of the active part comprises the following steps of: preparing Italy anchusa herb dry powder, extracting by using alcohol, mixing filtrate, recycling a solvent under reduced pressure to obtain crude extract; extracting the crude extract by using petroleum ether, ethyl acetate and n-butyl alcohol, drying the extract by distillation to obtain the active part. The active part is a natural plant antioxidant, has no side effect to a human body, and has application potential in antioxidant field.

Description

technical field [0001] The invention relates to the fields of plant extracts, medicines, health care products and cosmetics, in particular to the application of active parts of Buglossia italiana in the fields of antioxidant drugs, cosmetics and health care products. Background technique [0002] Antioxidants are substances that prevent the adverse effects of oxygen. It is a type of substance that can help capture and neutralize free radicals, thereby eliminating the damage caused by free radicals to the human body. The body's antioxidants are either synthesized by itself or supplied by food. All fruits and vegetables are high in natural antioxidants, such as vitamins A, C, E, P, polyphenols, etc. Bamboo leaf flavonoids extracted from bamboo leaves are a high-quality natural antioxidant, and tea also contains natural antioxidants, such as polyphenols. Studies have shown that natural antioxidants in fruits and vegetables have a protective effect. For example, vitamin E an...

Claims

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Application Information

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IPC IPC(8): A61K36/30A61K8/97A61P39/06A61Q19/08
Inventor 王琪谢周健戴沩
Owner 王琪
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