Traditional Chinese medicinal enteric-coated tablets for treating proctitis, colitis and irritable bowel syndrome, as well as preparation method and application thereof
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A technology for irritable bowel syndrome and proctitis, which is applied to pharmaceutical formulations, medical preparations containing active ingredients, sugar-coated pills, etc., and can solve the problems of rough process, less absorption of active ingredients, and slow disintegration.
Inactive Publication Date: 2014-01-22
王保安
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[0005] Although Guchang Zhixie Pills have a good curative effect, they are pills with rough craftsmanship, low quality standards, slow disintegration, and low bioavailability. Mo
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[0050] (1) Six kinds of traditional Chinese medicine, wash, dry (70℃), the dried ginger is divided into 2 parts, one part of dried ginger is crushed through a 120-mesh sieve into a fine powder for later use;
[0051] (2) Coptis chinensis, poppy husk, and Corydalis are crushed separately and passed through a 60-mesh sieve to form a coarse powder. After mixing, add 80% ethanol for reflux extraction for 2 times, add 960ml of 80% ethanol for reflux extraction for 2 hours for the first time, and extract for the second time Add 640ml of 80% ethanol for reflux extraction for 2 hours, filter, and 165g medicine residue for use; the filtrate recovers ethanol for use;
[0052] (3) In step (1), another portion of dried ginger and woody scent were crushed through a 60-mesh sieve into coarse powder, and the volatile oil was extracted by steam di...
[0062] The preparation method is the same as in Example 1, and 1000 tablets are made.
Embodiment 3
[0064] Chinese medicine raw material formula:
[0065] Black plum 800g coptis 400g dried ginger 400g 400g
[0066] Poppy shell 300g Corydalis 300g
[0067] The preparation method is the same as in Example 1, and 1000 tablets are made.
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Abstract
The invention provides traditional Chinese medicinal enteric-coated tablets for treating proctitis, colitis and irritable bowel syndrome, as well as a preparation method and application thereof. Active components for preparing the traditional Chinese medicinal enteric-coated tablets comprise the following traditional Chinese medicinal raw materials in parts by weight: 200-800 parts of smoked plum, 50-400 parts of golden thread, 50-400 parts of dried ginger, 50-400 parts of costustoot, 50-300 parts of pericarpium papaveris, and 50-300 parts of rhizoma corydalis. Clinical researches on ulcerative colitis prove that, the traditional Chinese medicinal enteric-coated tablets have a cure rate of 59.1 percent in a treatment group, and a total effective rate of 98.1 percent. Clinical researches on irritable bowel syndrome prove that traditional Chinese medicinal enteric-coated tablets have a complete remission rate of 67.8 percent in the treatment group, and a total effective rate of 95.2 percent. In clinical researches on proctitis, the traditional Chinese medicinal enteric-coated tablets are used for treating 36 cases, wherein 32 cases are cured, 3 cases are improved, 1 case is invalid, and the total effective rate is 88.8 percent. The researches prove that the enteric-coated tablets have remarkable advantages and improvement in treatment after the preparation and dose forms are improved, and are advantageous to clinical application. The traditional Chinese medicinal enteric-coated tablets are easily available in raw materials, simple in method and pollution free, is suitable for industrial production, and has higher application value.
Description
Technical field [0001] The invention relates to traditional Chinese medicines, in particular to colon-positioning enteric-coated tablets of traditional Chinese medicines, in particular to a traditional Chinese medicine enteric-coated tablets for treating colitis, proctitis and irritable bowel syndrome, and a preparation method and application thereof. Background technique [0002] Enteritis, especially ulcerative colitis (UC), is a chronic non-specific inflammatory bowel disease of the rectum and colon whose etiology is not very clear. The lesions are mainly limited to the large intestine mucosa and submucosa. The clinical manifestations are diarrhea, mucus pus and blood in the stool, and abdominal pain. The condition varies from severity to severity, and most of them present a recurring chronic course. Western medicine often uses aminosalicylic acid preparations, glucocorticoids, immunosuppressants, etc. to treat the disease. It has advantages in controlling the symptoms of UC, ...
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