Cranberry extract eye ophthalmic preparation and preparation method and uses thereof
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A technology of ophthalmic preparations and extracts, applied in the field of ophthalmic preparations, can solve the problems of no ophthalmic preparations and achieve good drug efficacy
Inactive Publication Date: 2014-06-18
CHENGDU JIANKABIN SCI & TECH
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At present, lingonberry products are mainly oral liquids, and there are no relevant reports on making bilberry or its extracts into ophthalmic preparations
Method used
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[0036] The preparation method of the ophthalmic preparation of the bilberry extract of the present invention is as follows: mix the active ingredients according to the above-mentioned parts by weight, then add water for injection and pharmaceutically acceptable excipients for ophthalmic preparations and mix evenly, and adjust the pH value of the solution to 7-8.5, and then filtered, subpackaged, and sterilized to obtain the ophthalmic preparation of the bilberry extract of the present invention; wherein, 0.4-1.0 g of propolis is contained in every 100 mL of the solution. The pharmaceutically acceptable excipients for ophthalmic preparations may be suspending agents, thickeners, antioxidants and the like.
[0037] The ophthalmic preparation of the bilberry extract of the present invention is used 3-6 times a day, 1 drop each time, and the frequency or dose of medication can be appropriately increased according to the condition.
[0038] The present invention also provides that ...
Embodiment 1
[0040] Embodiment 1 Preparation of bilberry extract ophthalmic preparation of the present invention
[0041] According to the ratio in Table 1, weigh the bilberry extract (obtained by extracting with 75wt% ethanol solution), add an appropriate amount of water for injection, mix well, adjust the pH of the solution to 7-8.5 with Pasteur borate buffer, and obtain The solution contains 0.4-1.0 g of propolis per 100 mL of the solution, and then is filtered, subpackaged and sterilized to obtain the bilberry extract eye drops of the present invention.
[0042] Table 1
[0043]
[0044] Continued Table 1
[0045]
[0046] After testing by Xing Rongyong, Song Guirong, Wang Yonggui and others from the Chemical Industry Synthetic Resin and Plastic Quality Supervision and Testing Center, the performance results of the bilberry extract ophthalmic preparation of the present invention are as follows:
[0047] Table 2
[0048]
[0049] Wherein, light yellow-brown sample and light ...
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Abstract
The invention relates to a cranberry extract eye ophthalmic preparation and a preparation method and uses thereof, and belongs to the technical field of eye ophthalmic preparations. The technical problem to be solved is to provide a cranberry extract eye ophthalmic preparation. The cranberry extract eye ophthalmic preparation comprises an active ingredient of cranberry extract. The cranberry extract eye ophthalmic preparation can effectively treat, prevent or alleviate cataract, glaucoma, vitreous opacity, macular degeneration, retinopathy, optic atrophy, keratitis, epiphora induced by wind, presbyopia, myopia, visual fatigue, blurred vision, conjunctival burn, conjunctivitis, corneal ulcer, palpebral ecgema, floaters or trachoma and other eye diseases. A novel preparation is provided for treating cataract, glaucoma, vitreous opacity, macular degeneration, retinopathy, optic atrophy, keratitis, epiphora induced by wind, presbyopia, myopia, visual fatigue, blurred vision, conjunctival burn, conjunctivitis, corneal ulcer, palpebral ecgema, floaters or trachoma and other eye diseases, and meets the strong demand of people for loving and protecting eyes.
Description
technical field [0001] The invention relates to an ophthalmic preparation of bilberry extract, a preparation method and application thereof, and belongs to the technical field of ophthalmic preparations. Background technique [0002] China is a big country with eye diseases: there are as many as 60 million cataract patients, 14 million glaucoma patients, 350 million myopia, and 4.5 million blind people due to eye diseases every year. Primary school students and junior high school students have myopia rates of 39% and 64% respectively. The eye is the most important sensory organ in vertebrates. Experts in many disciplines agree that people should love their eyes as much as they love their own lives! In 1996, 12 ministries and commissions of our country jointly announced that June 6th would be the "National Eye Care Day". The theme of "National Eye Care Day" in 2010 is "Pay attention to the eye health of the poor, and send light to millions of projects". [0003] Bilberrie...
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