Application of traditional Chinese medicine compound preparation in preparation of medicine for preventing and/treating brain damage due to novel drug addiction
A technology of compound preparations and new drugs, which is applied in the field of compound preparations of traditional Chinese medicine (marketed Chinese patent medicine Jitai Tablets), to achieve good social benefits, definite and significant curative effect, and unique effects
Inactive Publication Date: 2014-06-18
NAT ENG RES CENT FOR TRADITIONAL CHINESE MEDICINE
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Problems solved by technology
It is mainly used to alleviate the detoxification treatment of opioid addicts, and its application and treatment in other aspects have not been reported
Method used
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Embodiment Construction
[0019] Beneficial effect of the present invention is further elaborated by test example below: test example Chinese medicine Jitai tablet is to the evaluation research of the repairing effect of methamphetamine (METH) rat brain injury model
[0020] 1. Purpose of the experiment
[0021] Establish a brain injury model of methamphetamine rats, and explore the repairing effect of Jitai tablets on this brain injury.
[0022] 2. Experimental design
[0023] SD rats (200-300g) were divided into control group, prevention group, natural withdrawal group and Jitai tablet treatment group (three doses of high, medium and low). The model group, the prevention group and the three treatment groups were intraperitoneally injected twice a day with an interval of 6 hours, 15 mg / kg each time, and the administration concentration was 1.5 mg / ml, and the model was established in two days. The prevention group was intragastrically administered Jitai Tablets at a medium dose for seven consecutive ...
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The invention discloses an application of a traditional Chinese medicine compound preparation in preparation of a medicine for preventing and / treating brain damage due to novel drug addiction, which relates to medicine technical field, and the medicine is used for preventing and / or treating novel drug addiction. The traditional Chinese medicine compound preparation comprises the following bulk drugs by weight part: 65-85 parts of rhizoma corydalis, 10-26 parts of daturae flower, 100-135 parts of red sage root, 10-26 parts of Chinese cassia tree, 10-26 parts of radix aconiti lateralis preparata, 22-42 parts of aquilaria wood, 32-52 parts of banksia rose, 10-26 parts of dry ginger, 10-26 parts of cardamom, 10-26 parts of gen-seng, 70-110 parts of pearl powder, 65-85 parts of peach seed, 65-85 parts of safflower, 65-85 parts of Chinese angelica and 30-50 parts of Ligusticum wallichii. The traditional Chinese medicine compound preparation has the functions of reducing the methylamphetamine toxicity, and has adjusting and restoration effect for brain damage due to methylamphetamine. The traditional Chinese medicine compound preparation in preparation of medicine for preventing and / treating brain damage due to novel drug addiction has the advantages of obvious curative effect, unique effect, safety and reliability. The traditional Chinese medicine compound preparation in preparation of medicine for preventing and / treating brain damage due to novel drug addiction has important meaning for satisfying and clinical requirement and market demand.
Description
technical field [0001] The present invention relates to a new application of a traditional Chinese medicine compound preparation (marketed Chinese patent medicine Jitai Tablet), in particular to the application of a traditional Chinese medicine compound preparation in the preparation of drugs for preventing and / or treating brain damage caused by new drug addiction. Background technique [0002] The so-called new drugs are relative to traditional drugs such as opium and heroin, mainly referring to artificial chemically synthesized hallucinogens and stimulants, which are regulated by the international drug control convention and our laws and regulations, and directly act on the central nervous system of people. System, exciting or depressing, continuous use of psychotropic drugs (drugs) that can make people dependent, and make the human body slowly appear clinical manifestations such as brain damage in varying degrees. Most of the new drugs are derivatives of methamphetamine, ...
Claims
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IPC IPC(8): A61K36/9068A61P25/00
Inventor 韩梅姚譞沈平孃唐英张艳红陈欣王玲玲屠少昂仝晓宇
Owner NAT ENG RES CENT FOR TRADITIONAL CHINESE MEDICINE