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Tablet for quenching thirst and preparation method thereof

A technology of Xiaokeling tablet, which is applied in the field of Xiaokeling tablet and its preparation, can solve the problems of unsatisfactory curative effect, slow disintegration, and low curative effect

Inactive Publication Date: 2014-10-29
HEILONGJIANG JIANGHENG PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The existing Xiaokeling tablets have unsatisfactory curative effect due to the composition and process. The preparation is prepared by traditional technology, which has the disadvantages of slow disintegration and low curative effect.

Method used

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  • Tablet for quenching thirst and preparation method thereof
  • Tablet for quenching thirst and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Take 200g of Rehmannia glutinosa, 50g of Ligusticum edulis, 15g of Schisandra chinensis, 100g of Ophiopogon japonicus, 15g of Moutan cortex, 100g of Astragalus, 10g of Coptis chinensis, 17g of Poria cocos, 100g of trichosanthum pollen, and grind them into 60-mesh coarse powder, extract with carbon dioxide supercritical extraction method, extraction pressure 20Mpa, The extraction temperature is 20°C, the separator pressure is 10Mpa, the separator temperature is 40°C, the separation time is 2 hours, and the carbon dioxide flow rate is 20L per hour to obtain the extract; take the extract and dry it under reduced pressure at 60°C to obtain a dry paste; take the dry paste and add calcium sulfate 80g, using a high-energy nano-impact mill to pulverize into a mixed dry paste powder with a particle size of 200-300nm; take the mixed dry paste powder, 35g of microcrystalline cellulose, 35g of cross-linked polyvinylpyrrolidone, 35g of cross-linked sodium carboxymethylcellulose, hydro...

specific Embodiment 2

[0032] Take 200g of rehmannia root, 50g of ligusticum edulis, 15g of schisandra chinensis, 100g of Ophiopogon japonicus, 15g of Moutan cortex, 100g of astragalus, 10g of rhizoma coptis, 17g of poria cocos, 100g of trichosanthum pollen, and grind them into 60 mesh coarse powder, extract with carbon dioxide supercritical extraction method, extraction pressure 40Mpa, The extraction temperature is 40°C, the separator pressure is 20Mpa, the separator temperature is 60°C, the separation time is 4 hours, and the carbon dioxide flow rate is 40L per hour to obtain the extract; take the extract and dry it under reduced pressure at 80°C to obtain a dry paste; take the dry paste and add calcium sulfate 120g, using a high-energy nano-impact mill to pulverize into a mixed dry paste powder with a particle size of 200-300nm; take the mixed dry paste powder, 45g of microcrystalline cellulose, 45g of cross-linked polyvinylpyrrolidone, 45g of cross-linked sodium carboxymethyl cellulose, hydroxy P...

Embodiment 3

[0034] Take 200g of Rehmannia glutinosa, 50g of Ligusticum edulis, 15g of Schisandra chinensis, 100g of Ophiopogon japonicus, 15g of Moutan cortex, 100g of Astragalus membranaceus, 10g of Coptis chinensis, 17g of poria cocos, 100g of trichosanthes pollen, and grind them into 60-mesh coarse powder, extract with carbon dioxide supercritical extraction method, extraction pressure 30Mpa, The extraction temperature is 30°C, the separator pressure is 15Mpa, the separator temperature is 50°C, the separation time is 3 hours, and the carbon dioxide flow rate is 30L per hour to obtain the extract; take the extract and dry it under reduced pressure at 70°C to obtain a dry paste; take the dry paste and add calcium sulfate 100g, crushed into a mixed dry cream powder with a particle size of 200-300nm by a high-energy nano-impact mill; take the mixed dry cream powder, 40g of microcrystalline cellulose, 40g of cross-linked polyvinylpyrrolidone, 40g of cross-linked sodium carboxymethyl cellulose...

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Abstract

The invention discloses a tablet for quenching thirst and a preparation method thereof. The preparation method is characterized by comprising the following steps: taking 200g of radix rehmanniae, 50g of ligusticum, 15g of fructus schizandrae, 100g of radix ophiopogonis, 15g of moutan bark, 100g of astragalus membranaceus, 10g of coptis chinensis, 17g of poria cocos and 100g of radices trichosanthis; extracting the raw materials by adopting a supercritical carbon dioxide extraction method, drying the raw materials under reduced pressure, and crushing the raw materials into a nano dry paste by using a high-energy nano impact mill; adding a functional auxiliary material, and preparing into the tablet for quenching thirst. The disintegration time is obviously shortened, the curative effect is significantly superior to that of the commercially available tablet for quenching thirst, and a positive effect is obtained.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a Xiaokeling tablet and a preparation method thereof. Background technique [0002] Xiaokeling tablet nourishes qi and nourishes yin, clears heat and purifies fire, produces body fluid and quenches thirst. It is used for diabetes caused by deficiency of both qi and yin. Symptoms include polydipsia, polyphagia, polyuria, weight loss, shortness of breath, and type 2 diabetes mellitus with the above symptoms. The curative effect of the existing Xiaokeling Tablets is not ideal due to the composition and process, and the preparation is prepared by traditional techniques, which has the disadvantages of slow disintegration and low curative effect. Contents of the invention [0003] In order to overcome the above disadvantages, the present invention provides Xiaokeling tablets with fast disintegration speed and high curative effect and a preparation method thereof. [0...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61K9/20A61P3/10
Inventor 朱文江
Owner HEILONGJIANG JIANGHENG PHARMA TECH CO LTD