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Pharmaceutical preparation for treating nephritic syndrome and preparation method thereof

A technology of pharmaceutical preparation and yam, applied in the field of traditional Chinese medicine, can solve the problems of difficulty in adhering to the whole course of treatment, poor treatment effect of patients, long-term dependence and rebound, etc., and achieves the effect of reducing medication time, reducing rebound phenomenon and reducing side effects.

Inactive Publication Date: 2014-12-17
QINGDAO HUAREN TECH INCUBATOR
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Modern medicine commonly uses hormones, cytotoxic drugs, cyclosporine and other drug treatments, which have achieved certain curative effects, but often cause adverse reactions. The short-term curative effect is better but difficult to consolidate; Toxic and side effects, long-term dependence and rebound phenomenon occur, resulting in poor treatment effect, repeated illness, and even difficulty in adhering to the whole course of treatment

Method used

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  • Pharmaceutical preparation for treating nephritic syndrome and preparation method thereof

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preparation example Construction

[0056] The present invention also provides a preparation method of the above-mentioned pharmaceutical preparation, when the dosage form of the prepared pharmaceutical preparation is a capsule, specifically:

[0057] The first step is to grind Eclipta, Lycium barbarum, Lanbuzheng, Gynostemma, Codonopsis, Polygonatum, Epimedium, Rehmannia glutinosa, Gorgon seed, Sangjishen, yam, Morinda officinalis, dogwood, Wujiapi and Nansha ginseng separately , pass through a 20-mesh sieve, send it into a mixer by weight and mix it uniformly to obtain a mixture, put the mixture into a percolation cylinder, add 500g-700g of ethanol with an alcohol concentration of 70%-80% per 100g of the mixture, and heat it at 25°C Soak for 20 hours to 30 hours at ~35°C, adjust the valve of the percolation cylinder to slowly drip out the liquor liquid at a rate of 2 to 4 mL per minute, collect the dripping liquid, and obtain 700 mL to 1 L of percolation liquid, concentrated, removed ethanol solvent, dried, pu...

Embodiment 1

[0065] The preparation of embodiment 1 granule 1

[0066] Eclipta 45g, medlar 50g, blue cloth 50g, gynostemma 30g, codonopsis 80g, sealwort 45g, epimedium 35g, rehmannia glutinosa 40g, gorgon 45g, mulberry 40g, yam 45g, Morinda officinalis 35g, dogwood 40g , Wujiapi 25g, Nansha ginseng 35g are pulverized respectively, cross 20 mesh sieves, send into the mixer and stir and mix evenly to obtain the mixture, the mixture is packed into the percolation drum, and every 100g of the mixture is added with an alcohol concentration of 80% ethanol 600g, Soak for 20 hours at 25°C, adjust the valve of the percolation cylinder, slowly drip out the liquor liquid at a rate of 3 mL per minute, collect the dripping liquid to obtain 800 mL of percolation liquid, concentrate, and remove the ethanol solvent , dried, pulverized to obtain the first dry powder, 30g of Cortex Moutan, 30g of Eight Treasure Tea, 35g of Myrrh, 30g of Fragrant Tea, 35g of Ephedra, 30g of Ephedra, 40g of Poria and 25g of Ra...

Embodiment 2

[0067] The preparation of embodiment 2 granules 2

[0068] Eclipta 43g, medlar 48g, blue cloth 48g, gynostemma 28g, codonopsis 78g, sealwort 43g, epimedium 33g, rehmannia glutinosa 38g, gorgon 43g, mulberry 38g, yam 43g, Morinda officinalis 33g, dogwood 38g , Wujiapi 23g, Nansha ginseng 33g are pulverized respectively, cross 20 mesh sieves, send into the mixer and stir and mix evenly to obtain the mixture, the mixture is packed into the percolation drum, and every 100g of the mixture is added with an alcohol concentration of 80% ethanol 600g, Soak for 20 hours at 25°C, adjust the valve of the percolation cylinder, slowly drip out the liquor liquid at a rate of 3 mL per minute, collect the dripping liquid to obtain 800 mL of percolation liquid, concentrate, and remove the ethanol solvent , dried, pulverized to obtain the first dry powder, 30g of Cortex Moutan, 30g of Eight Treasure Tea, 33g of Myrrh, 28g of Fragrant Tea, 33g of Ephedra, 28g of Ephedra chinensis, 38g of Poria co...

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Abstract

The invention provides a pharmaceutical preparation for treating nephritic syndrome. The pharmaceutical preparation comprises the following crude drugs: herba ecliptae, medlar, aleppo avens, gynostemma pentaphyllum, radix codonopsis, rhizoma polygonati, cortex moutan, epimedium herbs, radix rehmanniae preparata, gorgon fruits, semen euryales, assorted Chinese herbal tea, myrrh, herba taxilli, Chinese yam, morinda officinalis, dogwoods, cortex acanthopanacis, radix adenophorae, rabdosia amethystoides, herba ephedrae, fructus broussonetiae, tuckahoe and liquorice. When the pharmaceutical preparation is used for treating nephritic syndrome, the side effect of a hormone can be reduced, and the rebound phenomenon caused after the hormone is used can be relieved; in addition, the pharmaceutical preparation can also be used for shortening the medication time of the hormone, improving the sensibility of the nephritic syndrome hormone, preventing infection, reducing the relapse frequency and increasing the cure rate of nephritic syndrome patients.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a pharmaceutical preparation for treating nephrotic syndrome and a preparation method thereof. Background technique [0002] Nephrotic syndrome (NS) is a group of clinical syndromes characterized by massive proteinuria, hypoalbuminemia, edema, hyperlipidemia and other metabolic disorders. It is the main feature of nephrotic syndrome. The main purpose of nephrotic syndrome treatment is to relieve symptoms, prevent complications and protect renal function. [0003] Western medicine believes that the disease is caused by the increased permeability of the basement membrane caused by various reasons, resulting in the loss of a large amount of plasma albumin from the urine. In terms of treatment, Western medicine mainly focuses on symptomatic treatment, such as blood pressure reduction, lipid reduction, anticoagulation, and diuresis. Modern medicine commonly use...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61K9/16A61K9/48A61P13/12
Inventor 不公告发明人
Owner QINGDAO HUAREN TECH INCUBATOR
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