Method of preparing 1,5-diazido-3-nitryl azapentane
A nitroazopentane and diazide-based technology, applied in the field of new energetic plasticizer 1, can solve problems such as increased process risk, difficult recycling, and potential safety hazards
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Embodiment 1
[0023] Add 35.7g of bis(2-chloroethyl)amine hydrochloride and 35ml of 98% nitric acid in a 500ml reaction flask, add 86ml of acetic anhydride dropwise to the reaction solution under stirring, and raise the temperature of the reaction solution to 75 ℃, and continue to keep warm for 3h. Add 100ml dichloromethane and 200ml water at the end of the reaction, and wash the organic phase with water-5%Na 2 CO 3 Washing - washing with water, drying with anhydrous magnesium sulfate, and concentrating the organic phase to obtain 24.9 g of light yellow oily liquid BCENA with a yield of 67% and a purity of 97.6% as measured by liquid chromatography.
Embodiment 2
[0025] In the 500ml reaction flask, add 35.7g of bis(2-chloroethyl)amine hydrochloride, 50ml of carbon tetrachloride, 18ml of 98% nitric acid, add 45ml of acetic anhydride dropwise to the reaction solution under stirring, after the dropwise addition, add The temperature of the reaction solution was raised to 60° C. and kept warm for 2 h. At the end of the reaction, add water for liquid separation, and wash the organic phase with water - 5% Na 2 CO 3 Washing with aqueous solution - washing with water, drying with anhydrous magnesium sulfate, and concentrating the organic phase to obtain 24.5 g of light yellow oily liquid BCENA with a yield of 66% and a purity of 97.2% as determined by liquid chromatography.
Embodiment 3
[0027] In the 500ml reaction flask, add 35.7g of bis(2-chloroethyl)amine hydrochloride, 60ml of dichloroethane, 26ml of 98% nitric acid, 70ml of acetic anhydride is added dropwise to the reaction solution under stirring, after the dropwise addition, the The temperature of the reaction solution was raised to 80° C. and kept warm for 4 h. After the reaction, add water solution, and the organic phase is washed with water - 5% Na 2 CO 3 Washing with aqueous solution - washing with water, drying with anhydrous magnesium sulfate, and concentrating the organic phase to obtain 25.2 g of light yellow oily liquid BCENA with a yield of 67% and a purity of 98.0% as measured by liquid chromatography.
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