Low bandgap bonding polymeric compositions and applications thereof
A composition and copolymer technology, applied in the direction of drug combination, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc.
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0133] NIR-mediated thermal ablation of cancer cells using aqueous or colloidal compositions of water-insoluble conjugated polymers
[0134] Materials and methods
[0135] All reagents were purchased from usual commercial sources and used without further purification unless otherwise stated. 4H-Cyclopenta-[1,2-b:5,4-b']dithiophene was purchased from Astar Pharma. THF was dried over Na / benzophenone ketal. Synthesis of 4,4-bis(2-ethylhexyl)-2,6-bis(trimethylstannyl)-4H-cyclopenta[2,1-b; 3,4- b']dithiophene, 4,7-dibromo-2,1,3-benzothiadiazole and 4,7-dibromo-2,1,3-benzoselenadiazole (see J.Hou, T.L. Chen, S. Zhang, H.-Y. Chen, Y. Yang, J. Phys. Chem. C 2009, 113, 1601-1607; Z. Zhu, D. Waller, R. Gaudiana, M. Morana, D. Muhlbacher, M. Scharber, C. Brabec, Macromolecules 2007, 40, 1981-1986; C.W. Bird, G.W.H. Cheeseman, A.A. Sarsfield, J. Chem. Soc. 1963, 4767-4770; I.H. Jung, H. Kim, M.- J.Park, B.Kim, J.-H.Park, E.Jeong, H.Y.Woo, S.Yoo, H.-K.Shim, J.Polym.Sci.Part A: Polym...
Embodiment 2
[0164] NIR-mediated thermal ablation of bacteria using a water-insoluble conjugated polymer
[0165] method
[0166] The hyperthermic interaction of PEDOT NT with bacterial species was assessed using two bacterial species with controlled surface thickness and molecular composition. Bacterial strains: Gram-positive Staphylococcus aureus ATCC 25923 and Gram-negative Escherichia coli ATCC 29055 were purchased from the American Type Culture Collection (ATCC). Bacteria were grown overnight (Staphylococcus aureus in tryptic soy broth and E. 8 The concentration of bacteria / ml suspension was used for exposure to nanoparticles. Purchase PEDOT NT from Sigma Aldrich. To aid in aqueous solubility of PEDOTNT, PEDOT NT was suspended in an aqueous solution containing 1% Pluronic (F127) surfactant. PEDOT NT was added to the bacterial suspension at a concentration of 0.1 mg / ml, and a 300 μL aliquot of the nanoparticle / bacteria solution was exposed to laser radiation. Bacterial suspensio...
Embodiment 3
[0169] NIR-mediated thermal ablation of cancer cells using aqueous or colloidal compositions of water-insoluble conjugated polymers
[0170] Materials and methods
[0171] All reagents were purchased from usual commercial sources and used without further purification unless otherwise stated. Furthermore, where relevant, all other materials were obtained and all measurements were carried out as described in Example 1 unless otherwise stated.
[0172] Aqueous Aqueous or Colloidal Compositions Forming PCPDTBSe Nanotubes and Spherical Nanoparticles
[0173] PCPDTBSe (5 mg) was dissolved in 2 mL of THF. This solution was injected rapidly into 8 mL of DI water containing Pluronic F127 (50 mg) under horn sonication. After 1 minute of sonication, the resulting mixture was centrifuged at 14,000 RPM for 15 minutes to separate the PCPDTBSe nanotubes from the substantially spherical nanoparticles. Figure 10 Transmission electron microscopy (TEM) images of isolated nanotubes are s...
PUM
| Property | Measurement | Unit |
|---|---|---|
| band gap | aaaaa | aaaaa |
| length | aaaaa | aaaaa |
| length | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
Login to View More