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Traditional Chinese medicine for treating myocardial fibrosis associated constipation

A technology for myocardial fibrosis and constipation, which is applied in the digestive system, pharmaceutical formulations, drug combinations, etc., and can solve the problems of little research on myocardial fibrosis.

Active Publication Date: 2015-03-25
澳润(山东)药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine is the treasure of Chinese medicine. There are some drugs that can protect organs and resist fibrosis. Many of them have carried out animal experiments and clinical observations on anti-hepatic fibrosis, but there are few studies on myocardial fibrosis.

Method used

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  • Traditional Chinese medicine for treating myocardial fibrosis associated constipation

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment 1

[0031] Weighing: 15 grams of three-lens, 15 grams of curcuma, 10 grams of woody incense, 10 grams of Cyperus cyperi, 15 grams of citron, 20 grams of bergamot, 20 grams of salvia miltiorrhiza, 10 grams of green peel, 10 grams of tangerine peel, 10 grams of citrus aurantium, citrus aurantium 15 grams, 20 grams of angelica, 20 grams of raw rehmannia, 20 grams of rehmannia, 15 grams of Chuanqiong, 20 grams of white peony, 15 grams of platycodon, 15 grams of Achyranthes bidentata, 10 grams of licorice, 15 grams of Bupleurum, 10 grams of peach kernels, 6 grams of flower, 6 grams of rhubarb, 15 grams of hemp seed, 9 grams of magnolia bark, and 15 grams of almond; add 8 times the amount of water, decoct for 1.5 hours, filter; add 6 times the amount of water to the filter residue, decoct for 1 hour, and filter; Combine the filtrates and concentrate to 120 grams, which is a decoction that meets the daily dosage of normal adults.

[0032] For the treatment of myocardial fibrosis associat...

specific Embodiment 2

[0033] Weighing: 15 grams of three-lens, 15 grams of curcuma, 10 grams of woody incense, 10 grams of Cyperus cyperi, 15 grams of citron, 20 grams of bergamot, 20 grams of salvia miltiorrhiza, 10 grams of green peel, 10 grams of tangerine peel, 10 grams of citrus aurantium, citrus aurantium 15 grams, 20 grams of angelica, 20 grams of raw rehmannia, 20 grams of rehmannia, 15 grams of Chuanqiong, 20 grams of white peony, 15 grams of platycodon, 15 grams of Achyranthes bidentata, 10 grams of licorice, 15 grams of Bupleurum, 10 grams of peach kernels, 6 grams of flower, 6 grams of rhubarb, 15 grams of hemp seed, 9 grams of magnolia bark, and 15 grams of almond; add 10 times the amount of water, decoct for 2 hours, filter; add 8 times the amount of water, decoct for 1.5 hours, and filter; The filtrates are combined, concentrated, dried, and packaged to obtain a powder that meets the daily dosage of a normal adult.

[0034] For the treatment of myocardial fibrosis associated with con...

specific Embodiment 3

[0035] Weighing: 15 grams of three-lens, 15 grams of curcuma, 10 grams of woody incense, 10 grams of Cyperus cyperi, 15 grams of citron, 20 grams of bergamot, 20 grams of salvia miltiorrhiza, 10 grams of green peel, 10 grams of tangerine peel, 10 grams of citrus aurantium, citrus aurantium 15 grams, 20 grams of angelica, 20 grams of raw rehmannia, 20 grams of rehmannia, 15 grams of Chuanqiong, 20 grams of white peony, 15 grams of platycodon, 15 grams of Achyranthes bidentata, 10 grams of licorice, 15 grams of Bupleurum, 10 grams of peach kernels, 6 grams of flower, 6 grams of rhubarb, 15 grams of hemp seed, 9 grams of Magnolia officinalis, 15 grams of almond; add 6 times the amount of water, decoct 3 times, decoct for 1 hour each time, combine the decoction liquid, concentrate, dry, Put it into the capsule shell to obtain the capsules that meet the daily dosage of normal adults.

[0036] For the treatment of myocardial fibrosis associated with constipation. Take it orally, ta...

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Abstract

The invention relates to a traditional Chinese medicine for treating myocardial fibrosis associated constipation. The traditional Chinese medicine is prepared from the following raw medicinal materials in parts by weight: 15 parts of common burreed rhizome, 15 parts of curcuma zedoaria, 10 parts of costustoot, 10 parts of nutgrass galingale rhizome, 15 parts of fructus citri, 20 parts of fingered citron, 20 parts of salvia miltiorrhiza, 10 parts of green tangerine peel, 10 parts of tangerine peel, 10 parts of immature bitter orange, 15 parts of bitter orange, 20 parts of Chinese angelica, 20 parts of radix rehmanniae, 20 parts of prepared radix rehmanniae, 15 parts of szechuan lovage rhizome, 20 parts of white paeony root, 15 parts of platycodon root, 15 parts of twotooth achyranthes root, 10 parts of liquoric root, 15 parts of Chinese thorowax root, 10 parts of peach seed, 6 parts of safflower, 6 parts of Chinese rhubarb, 15 parts of hemp seed, 9 parts of officinal magnolia bark and 15 parts of apricot kernel. Proved by clinical trials, the traditional Chinese medicine disclosed by the invention can be used for treating myocardial fibrosis associated constipation safely and effectively.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to a traditional Chinese medicine for treating myocardial fibrosis accompanied by constipation. Background technique [0002] Myocardial fibrosis, also known as myocardial calcification, is the result of myocardial fiber persistence and / or repeated aggravation of myocardial ischemia and hypoxia caused by moderate to severe coronary atherosclerotic stenosis, leading to gradual IHD that progresses to heart failure is known as chronic ischemic heart disease. Macroscopically: increased heart size and weight, all chambers dilated; wall thickness may be normal, with multifocal white fibrous cords or strips, or even transmural scarring; endocardium thickened and loses its normal luster , Sometimes organized mural thrombus can be seen. Under the light microscope, extensive, multifocal myocardial fibrosis, accompanied by atrophy and / or hypertrophy of adjacent myocardial fibers, often with ...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P9/00A61P1/10
CPCA61K9/0053A61K9/14A61K9/48A61K36/21A61K36/232A61K36/233A61K36/236A61K36/285A61K36/286A61K36/34A61K36/484A61K36/537A61K36/575A61K36/60A61K36/708A61K36/71A61K36/736A61K36/752A61K36/804A61K36/8905A61K36/9066A61K2236/331A61K2236/51A61K2300/00
Inventor 王建萍
Owner 澳润(山东)药业有限公司