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Traditional Chinese medicine for treating traumatic chronic osteomyelitis caused by liver and kidney deficiency and preparation method of traditional Chinese medicine

A technology for chronic osteomyelitis, liver and kidney deficiency, applied in medical formulas, medical preparations containing active ingredients, antibacterial drugs, etc., can solve problems such as easy recurrence, decline in curative effect, drug resistance variation, etc., to improve treatment effect, the effect of reducing the recurrence rate

Inactive Publication Date: 2015-05-20
韩明辉
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the irrational use of antibiotics, pathogenic bacteria often have drug resistance and mutation, which reduces the curative effect
Although surgical treatment can remove the lesion, it has the disadvantage of easy recurrence

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0042] The present invention also provides the preparation method of above-mentioned Chinese medicine, and the dosage form of described Chinese medicine is tablet, and its preparation method comprises the following steps:

[0043] Step 1: Mix the raw materials of the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 70-80% that is 2-4 times the mass of the mixture, heat and reflux for 1-3 hours, extract, and filter to obtain the first extraction liquid, the dregs obtained by filtering are added with ethanol with an alcohol concentration of 1 to 2 times the mass of dregs and 70 to 80% ethanol, heated and refluxed for 1 to 2 hours, extracted, filtered to obtain a second extract, and the first extract Combine with the second extract, concentrate under reduced pressure to remove the ethanol solvent, and dry to obtain a dry paste;

[0044] The second step: place the dry paste obtained in the first step to pulverize in an ultrafine ...

Embodiment 1

[0050] Example 1 tablet

[0051] Take 230g hair seven, 340g square rattan, 160g medlar root, 120g holly seed, 480g south candle seed, 130g ivy seed, 60g ivy, 80g iron silk fairy, 130g chasing wind umbrella, 460g loofah, 320g bark rattan, silk cotton 240g of wood, 170g of rabbit umbrella, 70g of Fenghua grass, 140g of orchid and bamboo ginseng, 90g of viburnum root, 70g of Bawangqi and 180g of black shell nan;

[0052] Prepare as follows:

[0053] The first step: mix the raw materials of the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 80% that is 4 times the mass of the mixture, heat and reflux for 3 hours, extract, filter to obtain the first extract, and filter the obtained medicinal Then add ethanol with an alcohol concentration of 80% that is twice the mass of the dregs, heat and reflux for 1 hour, extract, filter to obtain the second extract, combine the first extract and the second extract, and concentrate under red...

Embodiment 2

[0056] Embodiment 2 Granules

[0057] Take 210g hair seven, 320g square rattan, 180g medlar root, 150g holly seed, 460g south candle seed, 110g ivy seed, 90g ivy, 60g iron silk fairy, 110g chasing wind umbrella, 490g loofah, 340g bark rattan, silk cotton 220g wood, 190g rabbit umbrella, 80g Fenghuacao, 100g orchid and bamboo ginseng, 70g viburnum root, 80g Bawangqi and 160g black shell nan.

[0058] Prepare as follows:

[0059] The first step: mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration 3 times that of the mixture and be 85% ethanol, heat to boiling and reflux for 2 hours, filter, and slow down the mixture at a rate of 2ml per minute by percolation method. Slow percolation, collect the percolation liquid, then concentrate under reduced pressure at 0.05Mpa to a paste with a relative density of 1.00 at 70°C, and spray dry. The air inlet temperature of the spray dryer is 180°C, and the outlet air temperature is 80°C. ...

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Abstract

The invention provides a traditional Chinese medicine for treating traumatic chronic osteomyelitis caused by liver and kidney deficiency and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine comprises the following crude drugs: asiatic alectoria filament, treebine stems, llex cornuta roots, purpleflower holly fruits, lyonia ovalifolia seeds, lvy seeds, Japanese creepers, clematis chinensis, starflowerlike loosestrife roots or herbs, loofah sponge, creeping mallotus roots or leaves, euonymus bungeanus, syneilesis maxim, borreria stricta, epipactis mairei schltr., viburnum dilatatum thunb, wild snapweed root-tubers and lindera megaphylla. If the traditional Chinese medicine provided by the invention is matched with operation and western medicine treatment, the effect for treating traumatic chronic osteomyelitis caused by liver and kidney deficiency can be remarkably improved, and the recurrence rate can be effectively reduced.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine for treating traumatic chronic osteomyelitis of liver and kidney deficiency type and a preparation method thereof. Background technique [0002] Traumatic chronic osteomyelitis refers to chronic inflammation caused by bacterial infection and destruction of local bone tissue due to trauma or iatrogenic reasons. The disease is caused by various factors after trauma and develops due to improper treatment or delayed diagnosis and treatment. Patients may have chronic wasting symptoms such as weight loss and anemia. After the sinus tract is formed, it will not heal for a long time, and there will be discharge of purulent secretions, and sometimes small pieces of sequestrum will be discharged. In some cases, bone defects and fracture nonunions can be formed, and there is a certain rate of disability an...

Claims

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Application Information

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IPC IPC(8): A61K36/90A61K36/898A61P19/08A61P31/04A61K9/20A61K9/16
Inventor 张阳高晓燕魏秀芝
Owner 韩明辉
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