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A kind of extraction method of papaya flavonoids

An extraction method and technology of papaya with smooth skin, applied in the direction of drug combination, medical formula, plant raw materials, etc., can solve the problems of low purity, difficult to crush, and low content of total flavonoids, and achieve simple operation process, not harsh conditions, and low cost Effect

Inactive Publication Date: 2017-10-20
CHINA PAULOWNIA RES CENT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current extraction method of papaya flavonoids has the following technical defects: the extraction rate is low and the total flavonoid content in the extract is low, and the purity after purification is low
In addition, the hardness of papaya with papaya is relatively high, and it is difficult to fully crush it, which will also cause the flavonoids in papaya with papaya to be extracted more thoroughly.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] A method for extracting papaya flavonoids, comprising the steps of:

[0027] (1) Pick the fresh fruit of papaya with smooth skin, wash it, cut and remove the seeds to get the pulp, add the pulp and water to a tissue grinder and mash, the mass ratio of pulp and water is 1:0.5.

[0028] (2) Add the crushed material to a beater for beating, and the diameter of the sieve hole of the beater is 0.4 mm.

[0029] (3) The slurry obtained in step (2) was naturally air-dried at 15°C.

[0030] (4) Grinding the air-dried product in step (3), then grinding and discharging with a superfine pulverizer to obtain papaya powder with smooth skin.

[0031] (5) According to the mass ratio of papaya powder and water of 1:3, 100 grams of papaya powder with papaya was added to 300 grams of water, soaked for 24 hours to obtain intermediate product A; The total amount of flavonoids in the intermediate product A was determined to be 2876mg.

[0032] (6) At 5°C, according to the mass ratio of pa...

Embodiment 2

[0038] A method for extracting papaya flavonoids, comprising the steps of:

[0039] (1) Pick the fresh fruit of papaya with smooth skin, wash it, cut and remove the seeds to obtain the pulp, add the pulp and water to a tissue grinder and mash, the mass ratio of pulp and water is 1:1.

[0040] (2) Add the crushed material to a beater for beating, and the diameter of the sieve hole of the beater is 0.4mm.

[0041] (3) The slurry obtained in step (2) was naturally air-dried at 25°C.

[0042] (4) Grinding the air-dried product in step (3), then grinding and discharging with a superfine pulverizer to obtain papaya powder with smooth skin.

[0043] (5) According to the mass ratio of papaya powder and water of 1:4, 100 grams of papaya powder with papaya was added to 400 grams of water, soaked for 48 hours to obtain intermediate product A; The total amount of flavonoids in the intermediate product A was determined to be 2768 mg.

[0044] (6) At 5°C, according to the mass ratio of p...

Embodiment 3

[0050] A method for extracting papaya flavonoids, comprising the steps of:

[0051] (1) Pick the fresh fruit of papaya with smooth skin, wash it, cut and remove the seeds to obtain the pulp, add the pulp and water to a tissue grinder and mash, the mass ratio of pulp and water is 1:0.8.

[0052] (2) Add the crushed material to a beater for beating, and the diameter of the sieve of the beater is 0.5 mm.

[0053] (3) The slurry obtained in step (2) was naturally air-dried at 20°C.

[0054] (4) Grinding the air-dried product in step (3), then grinding and discharging with a superfine pulverizer to obtain papaya powder with smooth skin.

[0055] (5) according to the mass ratio of papaya powder and water is 1:3.5, 100 grams of papaya powder is added to 350 grams of water, soaked for 48 hours, to obtain intermediate product A; using the high performance liquid chromatography of the prior art The total amount of flavonoids in the intermediate product A was determined to be 2905mg. ...

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PUM

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Abstract

The invention discloses a method for extracting flavonoids in chaenomeles sinensis. The method comprises steps as follows: (1), pulp and juice of chaenomeles sinensis are added to a tissue triturator; (2), pulping is performed; (3), the pulp is air-dried; (4), an air-dried product is smashed, ground into powder and discharged, and powder of the chaenomeles sinensis is obtained; (5), the powder of the chaenomeles sinensis is added to water and soaked, and an intermediate product A is obtained; (6), an organic solvent is added to the intermediate product A and stirred; (7), the mixture is left to stand for layering, an organic phase is separated, an aqueous phase is extracted twice with the same volume of an organic solvent, and the organic phase is obtained after three times of mixing; (8), a solid drying agent is added to the organic phase, the solid drying agent is removed, the mixture is subjected to reduced pressure evaporation on a rotary evaporator, and the organic solvent is removed; (9), a product obtained from the step (8) is absorbed and purified with D140 macroporous resin. The method for extracting the flavonoids in chaenomeles sinensis is simple in operation process, low in cost and suitable for large-scale popularization and application, and is not harsh for required conditions.

Description

technical field [0001] The invention relates to a method for extracting functional components in papaya, in particular to a method for extracting flavonoids from papaya with light skin. Background technique [0002] Papaya (Chaenomeles sinensis) is a plant of the genus Papaya in the family Rosaceae. Because the skin of the fruit is still smooth and does not shrink after drying, it has another name called papaya with light skin. Its fruit is rich in nutrition, rich in organic acids, amino acids, polysaccharides, flavonoids, triterpenes and their glycosides and other compounds. One of the most valuable new economic tree species, the market prospect is broad. At present, papaya has become a characteristic medicinal material and processed edible fruit in many places such as Heze in Shandong, Yunxian in Hubei, Baihe in Shaanxi, and Tongbai in Henan. [0003] For a long time, papaya with light skin has been cultivated with seedlings to build orchards, and the output is uneven. ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/732A61P39/06
CPCA61K36/732A61K2236/15A61K2236/31A61K2236/331A61K2236/51A61K2236/55
Inventor 岳华峰李相宽马梦婕杨超伟刁松锋刘国顺狄海霞段伟王炜炜周晓星赵广杰杨绍彬汪志强郝荣昌
Owner CHINA PAULOWNIA RES CENT
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